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I agree that it is more specific to Celiac than any other disease but there is a point to looking at it by a patient by patient basis. Theoretically 95 out of 100 patients with elevated TTG have Celiac but the University of Chicago used these theories to also swing the ball the other way: "tTG are thought to be 97-98% specific, but by definition this means...

Yeah but there is a long list of things to investigate before claiming someone is "just in denial". It looks to me like the original poster probably has Celiac but I find Takala constantly makes posts that are so ignorant and inflammatory so I was going after that. To just group everyone who has looked at a wide spectrum of issues WITH their doctors and ruled...

What? So people have inconclusive tests and follow up tests come back negative while their not so related to Celiac symptoms DO NOT improve on a gluten free diet and you think that it means they are just in denial about having Celiac? This, as many of your posts do, shows how little you know about the blood tests or OTHER diseases/issues that go on in the...

Ok, well Lupus at 48 is rather uncommon. Even if you did have Lupus, why would you end your life? Would you really want to succumb to this? You have to be stronger than that! My grandfathers brother had Lupus, guess what age he lived to? 92, no I am not kidding you NINETY-TWO. My grandfather who was perfectly healthy lived until 88. Lupus is known to often...

Robb, I am really sorry to hear how poorly you feel, hopefully you can get to the bottom of it soon. The thing with the gluten free diet is that it does not require a prescription.... You are free to do it on your own, so why not give it a try? Desperate times call for desperate measures and you can very well have NCGI. That being said I think it is important...

"Anti-CCP is a very useful test to order during the Open Original Shared Link of a person who may have rheumatoid arthritis. If present in such a patient at a moderate to high level, it not only confirms the diagnosis but also may indicate that the patient is at increased risk for damage to the joints. Low levels of this antibody are less significant. In...

As Nicole said, you need to let us know which test it is. The anti-gliadin test does not differentiate between autoimmune and non-autoimmune gluten intolerance (Celiac, vs. NCGI). Although both can cause the same symptoms NCGI as we know it does not cause other complications or issues if gluten is ingested while Celiac can trigger other autoimmune or even...

Type 1 diabetes associated and tissue transglutaminase autoantibodies in patients without type 1 diabetes and coeliac disease with confirmed viral infections. Open Original Shared Link Helicobacter pylori infection is associated to increased levels of tissue transglutaminase in gastric mucosa cells Open Original Shared Link(01)83332-1/abstract Anti-transglutaminase...

The reason your biopsy was negative was because you were gluten free for 2 years before, unless you had refractory sprue there is no way your intestines would had not fully healed on a strict gluten free diet. When your new doctor speaks of your blood tests I wonder which ones were given. While the DGP is very sensitive and specific to Celiac it was not...

Were your gliadin test results "anti-gliadin" or "deamidated gliadin"? Anti-gliadin does not differentiate between autoimmune and non-autoimmune forms of gluten intolerance. That means that both Celiac and non-Celiac Gluten Intolerance as well as some "healthy" population samples will show up positive on the result while the deamidated is pretty specific...

I wasn't aware that it was a TTG blood test, I thought you were speaking of the fecal gliadin tests.

Doctors would call that "biological variation". I don't think the test will be positive for absolutely no reason however it is elevated in MANY different disorders and infections. Studies have shown transient elevation during an infectious illness and it is notorious for being false positive in those with other autoimmune diseases (20 percent false positive...

Nicole, If I had a dime for every doctor that thought they could diagnose the thyroid on TSH alone I would be rich.

Although it seems extremely likely that you have the disease due to your symptoms and your daughter having it (was she biopsy confirmed?) I still have to inform you that all of these take home gluten tests are next to useless. There is a reason these tests are sold directly to the public and not adopted by the medical community - they are garbage. Of course...

That is a very high result. Keep in mind TTG can also be elevated in Crohn's, which your mother had. Along with the biopsy it will probably be worth your while to get the Deamidated Gliadin IgA/IgG tests along with the endomysial. That will help isolate the potential causes.