Celiac.com 05/19/2015 - What should be the screening standards for celiac disease in the general population, and in high-risk groups?
To gain an answer, a team of researchers recently set out to review medical literature on screening for celiac disease in relation to the current World Health Organization (WHO) criteria for mass screening.
For their study, the team conducted a PubMed search to identify indexed papers on celiac disease screening published between 1900 and 1 June 2014. The team then read the papers for all relevant abstracts.
They found that, although celiac disease fulfills several WHO criteria for mass screening, such as high prevalence, and available treatment and difficult clinical detection, current medical evidence does not support mass celiac disease screening,
Also, treatment of asymptomatic celiac disease not been shown to be cost effective, nor likely reduce the excessive risk of severe complications, thus leading to higher QOL
The team points out that active case-finding may be appropriate, even though many celiac patients will still be missed by this strategy.
They also note that, even though proof of medical necessity or benefit is still lacking, mass celiac disease screening may be appropriate for high-risk groups.