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Mcmaster Researchers Find Possible Treatment For Celiac Disease - Cbc.ca

Scott Adams

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Scott Adams
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CBC.ca

People with celiac disease always have to be vigilant because even very small amounts of gluten can damage their intestinal lining, she said, which usually recovers slowly from past damage. Verdu said treatment with elafin could strengthen the ...

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    • Scott Adams
      Is my dishwasher glutening me?

      By Scott Adams · Posted

      Your diligence in managing cross-contamination is impressive, and it does sound like the dishwasher could be the culprit—especially since your symptoms started around the time you got it. Even if plates and cutlery look clean, gluten proteins can linger if the dishwasher isn’t effectively removing residue. Grittiness or visible marks suggest it may not be cleaning thoroughly, and gluten could still be present even after a cycle. A few things to try: Run the dishwasher on the hottest, longest cycle (if possible) to improve cleaning. Hand-wash your dedicated gluten-free dishes with a fresh sponge (not one used for gluten) as a temporary test—see if symptoms improve. Check the dishwasher’s filter for buildup (gluten crumbs could be recirculating). Since you felt fine away from home, the issue is likely in your kitchen, and the dishwasher timing is suspicious. Keep troubleshooting—you’re on the right track!
    • Scott Adams
      Inflammation and Menier’s disease link?

      By Scott Adams · Posted

      Your situation sounds challenging, and it’s great that you’re taking a proactive approach to uncovering potential triggers for your Ménière’s symptoms. Given your family history of celiac, low folate, ferritin, and total protein (all of which can hint at malabsorption), and your possible IgA deficiency, further investigation is absolutely warranted. Since your tTG-IgA was extremely low (<0.02), IgA deficiency is a strong possibility—this can cause false negatives on standard celiac blood tests. The next steps should include: Total IgA Level – This will confirm whether you have an IgA deficiency. If so, your GP should order IgG-based celiac tests (e.g., DGP-IgG or tTG-IgG). Endoscopy with Biopsies – Even if blood tests are inconclusive, an endoscopy (with multiple duodenal biopsies) is the gold standard for diagnosing celiac disease, especially since you have symptoms and lab markers suggesting malabsorption. Additional Nutrient Testing – Since you already have low folate and ferritin, checking other deficiencies (B12, vitamin D, zinc, etc.) may help build the case for intestinal damage. Given that Ireland has high celiac prevalence, your GP should be open to further testing. If they’re hesitant, emphasize your family history, IgA deficiency risk, and debilitating neurological symptoms (vertigo and brain fog are recognized in some gluten-sensitive cases). In the meantime, you might consider a strict gluten-free trial after completing diagnostics, as going gluten-free beforehand could obscure test results. Some people with gluten sensitivity (even without full celiac) see improvements in inflammation-driven conditions like Ménière’s. Wishing you clarity and relief—keep advocating for yourself!
    • AllyJR
      Confused about my results

      By AllyJR · Posted

      Very interesting! My whole family is full of autoimmune disease. Celiac, Lupus, Addison's, Graves and Hashimotos. My great grandmother who had celiac passed away due to digestive complications and my grandmother (her daughter) is 88 and is struggling with severe life-threatening digestive issues. She was never diagnosed but I am suspicious she may have celiac. My mom has Schmidt's (combo of Addison's and Hashimotos). Now that I have 2 autoimmune conditions I am definitely concerned that my kids have a very high risk of developing an autoimmune disease. 
    • knitty kitty
      Help figuring out stomach pain

      By knitty kitty · Posted

      Seems like you've been exploring all the possibilities.  Good job!    Fructose Malabsorption might cause intestinal discomfort. You might cut back on fruit for a bit.   Gastroparesis can cause squeezing contractions randomly.  Thiamine and the B vitamins would help. Has your daughter been checked for vitamin deficiencies?  Is she taking any vitamin supplements?   The B vitamins are mostly found in meats and liver.  Increasing B vitamins may help.   Continue keeping track of her symptoms.  Keep us posted on your progress!
    • trents
      Confused about my results

      By trents · Posted

      @AllyJR, older studies placed the likelihood of the first degree relatives of those with celiac disease also developing celiac disease at about 10%. Two more recent and large sample studies place it at almost 50%. There are likely multiple epigenetic factors involved in the development of active celiac disease, one of which may be the consumption of modern cultivars of wheat which, through genetic manipulation, contain multiple times the gluten content of ancient wheat. You will have to decide whether or not it is prudent and necessary to require your children who have not yet developed active celiac disease (and who may not ever develop it) to eat gluten free. There certainly will be a social cost for them if you do. If you do decide to go that direction, it would certainly make it easier for you to be consistent in avoiding gluten in the home and so, to keep yourself safe.  
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