Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Sertraline HCL - Gluten free? Experiences?

Grant Laws
 Share

Recommended Posts

Grant Laws Newbie
Grant Laws
Posted

Hi All,

I have been diagnosed with celiac for about 2 years and was recently prescribed Sertraline HCL and I have been experiencing some celiac-like symptoms. I know these symptoms are expected at first, so I’m keeping my cool. My prescription is manufactured by Lupin Pharmaceuticals. I reached out to them and wasn’t able to get information on one of the starch ingredients, but they told me it was gluten free. Does anyone have any experience with Setraline HCL from Lupin? What should my next step be? 
 

thanks 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


plumbago Experienced
plumbago
Posted

I would keep at it with the company - complemented by some research online, using terms like gluten free psychiatry, etc.

If you have to, write a letter to someone at quality control at Lupin.

Wheatwacked Veteran
Wheatwacked
Posted

I am not a doctor. If you don't eat gluten because of the effects, why is ok to take a medication that has the same effect on you as gluten, whether or not it has gluten is irrelevant  in my mind.

How low is your vitamin D plasma level? There is a condition called Seasonal Affective Disorder. It is winter depression due to low vitamin D (no UV rays). During the summer we store vitamin D for use during the winter. Trouble is nowaday we cover up and use sunscreen and we don't get nearly enough in diet. For a Celiac with malabsorption syndrome the vitamin absorbed through diet in the western diet is likely next to none.

 Vitamin D and Depression: Where is all the Sunshine?

Vitamin D and the Immune System

For that feeling that is has to be done now that you can't shake look at your Lithium intake. It should be about one gram a day. Traditionally we get it in drinking water. With everyone drinking bottle water.....

"However, a number of observations suggest that environmentally relevant lithium doses may also exert beneficial health effects, leading to a decrease in the rate of suicides and levels of violence." Is Lithium a Micronutrient? From Biological Activity and Epidemiological Observation to Food Fortification

 

knitty kitty Grand Master
knitty kitty
Posted
(edited)

@Grant Laws,

Welcome to the forum!

I was prescribed Sertraline HCl under the name Zoloft.  I became very ill. 

Please remember that the gastrointestinal tract has a limited vocabulary.  Every tummy ache isn't necessarily caused by gluten.

Through research, I found that gluten free Celiac patients on PPIs, NSAIDs and SSRIs (like Zoloft) continue to have inflammation.   

Here's another article showing the same effect....

Combined use of SSRIs and NSAIDs increases the risk of gastrointestinal adverse effects

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884264/

 

Selective Serotonin Reuptake Inhibitors (SSRIs), like Zoloft, prevent serotonin (a neurotransmitter in the brain) from being reabsorbed.  Too much serotonin in the brain can cause Serotonin Syndrome, a very unpleasant and serious condition which may go unrecognized by doctors.  Watch for serotonin syndrome when increasing dosages of SSRIs, when changing from one antidepressant to another, and when changing classes of antidepressants.  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865832/

And...

https://www.mayoclinic.org/diseases-conditions/serotonin-syndrome/symptoms-causes/syc-20354758

Serotonin Syndrome has a connection to Thiamine Deficiency.  Thiamine is needed for the uptake and release of serotonin in the brain.  Without sufficient thiamine, the serotonin may build up, resulting in Serotonin Syndrome.  

https://www.hormonesmatter.com/serotonin-syndrome-thiamine-connection/

 

Ironically, Sertraline HCl is a drug that has been found to CAUSE Thiamine deficiency by blocking the Thiamine Transporters that bring thiamine into cells.  Other drugs that cause Thiamine deficiency by blocking Thiamine Transporters are Metformin, ACE inhibitors, and thiazide diuretics.  

Even more ironic is the fact that supplementing Thiamine while taking antidepressants improves patient mood faster than antidepressants alone.  Thiamine improved mood before antidepressants kicked in weeks later.

Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial

https://pubmed.ncbi.nlm.nih.gov/26984349/

 

Brain health is affected by nutritional deficiencies.  The brain cannot function properly if the required vitamins and minerals are not available.

Correcting nutritional deficiencies is part of proper follow up care for Celiac people.  

Understanding nutrition, depression and mental illnesses

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738337/

And...

The Role of Vitamins and Minerals in Psychiatry

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046018/

 

Discuss with your doctor and nutritionist the benefits of supplementing with a B Complex, Vitamin C and D, magnesium and extra Thiamine while your intestines are healing.

Edited by knitty kitty
Add link and information

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. knitty kitty
      - knitty kitty replied to NCalvo822's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      3

      Newly Diagnosed

      Hello, @NCalvo822, Blood tests for Celiac Disease test for antibodies our bodies make in response to gluten exposure. These Tg IgA 2 antibodies mistakenly attack our own bodies, causing problems in organs and tissues other than just the digestive tract. Joints can ache, thyroid problems or the pancreas can develop. Ataxia is just one of over two hundred...
    2. knitty kitty
      - knitty kitty replied to Rebeccaj's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      symptoms.

      @Rebeccaj, When you smell toast or pasta cooking, that means that particles of that food are floating around in the air. Airborne gluten can then be inhaled and swallowed, meaning the food particles get into your digestive tract. If you're careful to avoid gluten and are still having symptoms, those symptoms could be caused by vitamin deficiencies...
    3. Rebeccaj
      - Rebeccaj replied to Rebeccaj's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      symptoms.

      ok thanks for your advice. But my question was what happens when someone you know in a house is cooking pasta or toast that's flour Airbourne without eating.?
    4. knitty kitty
      - knitty kitty replied to CeliacPI's topic in Related Issues & Disorders
      8

      Lymphocytic Colitis with Celiac

      Do discuss this recent article with your doctors. Thiamine Vitamin B 1 is important to intestinal health. Thiamine deficiency can occur in Celiac Disease due to malabsorption. Supplementing with a B Complex, Benfotiamine, and Vitamin D can help symptoms. Thiamine deficiency aggravates experimental colitis in mice by promoting glycolytic reprogramming...
    5. knitty kitty
      - knitty kitty replied to lmemsm's topic in Gluten-Free Foods, Products, Shopping & Medications
      5

      Finding gluten free ingredients

      Do keep in mind that most gluten free flours are not enriched nor fortified with vitamins and minerals like gluten containing flours are required to do. Consuming a diet high in carbohydrates without sufficient B vitamins to digest and process them into energy can lead to High Calorie Malnutrition and weight gain. Deficiency symptoms of B vitamins...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      130,508
    • Most Online (within 30 mins)
      7,748
    Bringmesunshine
    Newest Member
    Bringmesunshine
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • knitty kitty
      Newly Diagnosed

      By knitty kitty · Posted

      Hello, @NCalvo822, Blood tests for Celiac Disease test for antibodies our bodies make in response to gluten exposure.  These Tg IgA 2 antibodies mistakenly attack our own bodies, causing problems in organs and tissues other than just the digestive tract.  Joints can ache, thyroid problems or the pancreas can develop.  Ataxia is just one of over two hundred symptoms of Celiac Disease. Some people with Celiac Disease also make tTg IgA 6 antibodies in response to gluten exposure.  The tTg IgA 6 antibodies attack the brain, causing ataxia.  These tTg IgA 6 antibodies are also found in people with Parkinson's disease, though they may not have Celiac Disease.  First degree relatives (parents, siblings, children) of those diagnosed with Celiac should be tested as well.  Celiac is genetic.  Your mom and sister should be tested for Celiac, too!   Definitely a good idea to keep to a gluten free diet.  
    • knitty kitty
      symptoms.

      By knitty kitty · Posted

      @Rebeccaj,  When you smell toast or pasta cooking, that means that particles of that food are floating around in the air.  Airborne gluten can then be inhaled and swallowed, meaning the food particles get into your digestive tract.   If you're careful to avoid gluten and are still having symptoms, those symptoms could be caused by vitamin deficiencies.  
    • Rebeccaj
      symptoms.

      By Rebeccaj · Posted

      ok thanks for your advice. But my question was what happens when someone you know in a house is cooking pasta or toast that's flour  Airbourne without eating.?
    • knitty kitty
      Lymphocytic Colitis with Celiac

      By knitty kitty · Posted

      Do discuss this recent article with your doctors.  Thiamine Vitamin B 1 is important to intestinal health.  Thiamine deficiency can occur in Celiac Disease due to malabsorption.  Supplementing with a B Complex, Benfotiamine, and Vitamin D can help symptoms.   Thiamine deficiency aggravates experimental colitis in mice by promoting glycolytic reprogramming in macrophages https://pubmed.ncbi.nlm.nih.gov/39890689/#:~:text=Our mechanistic study revealed that,necessary to protect against colitis. "Conclusion and implications: Our study provides evidence linking thiamine deficiency with proinflammatory macrophage activation and colitis aggravation, suggesting that monitoring thiamine status and adjusting thiamine intake is necessary to protect against colitis."
    • knitty kitty
      Finding gluten free ingredients

      By knitty kitty · Posted

      Do keep in mind that most gluten free flours are not enriched nor fortified with vitamins and minerals like gluten containing flours are required to do.   Consuming a diet high in carbohydrates without sufficient B vitamins to digest and process them into energy can lead to High Calorie Malnutrition and weight gain. Deficiency symptoms of B vitamins resemble gastrointestinal symptoms when after eating gluten.  Gastrointestinal Beriberi is a form of Thiamine deficiency.   Do talk to your doctors about supplementing with essential nutrients while on the gluten free diet, especially if you're consuming processed foods.
×
×
  • Create New...