Domperidone

[celiac3270]

Hi,

As I've mentioned in another post somewhere, the dr. would like me to try a medication that isn't FDA approved, but used in Canada, the UK, and much of Europe. Before using it, however, I'd like to find out if anyone's heard of it or used it and I'll do some research. The doctor says he's been using it on patients for over a decade, but whenever you're taking something that's not FDA approved, you want to be careful, regardless...by the way, this is to speed up my digestion....i've got to go, so I can't provide more detail right now, but i'll post back later...anyway, anyone heard of it?

[Carriefaith]

Here are some good links I found. Which give quite a bit of info. I use the Open Original Shared Link site to read ingredients on mediactions quite often (I like doing my own research on things, just in case)

1. Open Original Shared Link

2. Open Original Shared Link

3. Open Original Shared Link

This info from the first link I gave may be one of the resons why the US hasn't FDA approved it:

Manufacturers' Warnings In Clinical States: Dopamine receptor blocking agents elevate prolactin levels; the elevation persists during chronic administration. Tissue culture experiments indicate that approximately one-third of human breast cancers are prolactin dependent in vitro, a factor of potential importance if the prescription of these drugs is contemplated in a patient with previously detected breast cancer. Although disturbances such as galactorrhea, amenorrhea, gynecomastia, and impotence have been reported, the clinical significance of elevated serum prolactin levels is unknown for most patients. An increase in mammary neoplasms has been found in rodents after chronic administration of dopamine receptor blocking agents. Neither clinical studies nor epidemiologic studies conducted to date, however, have shown an association between chronic administration of these drugs and mammary tumorigenesis. The available evidence is considered too limited to be conclusive at this time.

Hope this helps!

-Carrie

[Canadian Karen]

Hi celiac3270:

I have taken that medication but for a whole different reason.

When I had my twin boys, they were nine weeks premature and were in the special care unit at hospital for almost 1 month. They were too small to breastfeed, they were fed through a tube in the nose. I was pumping breastmilk for them. Unfortunately, I have never been very successful in producing milk in all of my pregnancies (4 kids, three pregnancies....) so the doctor prescribed this medication to assist in milk production. Unfortunately, it bothered my stomach way too much for me to be able to continue it and I finally made the decision to switch the babies to formula (for their sake and well as my sanity.....)

Don't know how this will help you, but that's my experience with this drug....

Karen

[celiac3270]

Thanks, Carrie....I'll definitely check out those links later (I have to get ready for school now) .

Karen.....it was helpful to hear your experience--even if it's for a different purpose--because it seems safer in my eyes if I know that you've taken it and been fine.