Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Lab Tests


mouth

Recommended Posts

mouth Enthusiast

sorry all for the big wrtiting.. need new glasses.. ok here we go vent first then the lab test that was done. and please somebody tell me what it is..

THE LAB DID THE WRONG TEST. IT WENT TO MAYO CLINIC.. IT SHOULD OF GONE TO PROMETHEUS I JUST FOUND OUT!!!!!!! :angry:

OK HERE IS THE LISTING OF THE TESTS THAT WERE DONE INSTEAD OF THE DQ2 AND DQ8-- WHICH BY THE WAY WERE DONE AGAIN TODAY AND SENT TO PROMETHEUS..

1ST TEST

RETICULIN ANTIBODIES IgG Negative

--EXPECTED VALUES----

NEGATIVE

test performed by

MAYO CLINIC

ETC.

NEXT TESTS

HLA A,B, AND C ANTIGEN SEE TEST

TYPING

SEE COMMENTS

HI EXPEXCTED

TEST RESULT LO UNITS VALUES

HLA CLASS 1 MOL. PHENOTYP0E, B

A LOCUS 1.30

B LOCUS 8.13

C LOCUS 6.7

Bw 4.6

METHOD PCR

HLA typing defined by molecular techinques. Serologic

equivalentw of defined alleses are reported

This test is performed persuant to a lixense afreement with

Roche Molecular systems inc

Test performed by

mayo clinic etd..

:angry:


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



nora-n Rookie

Those are not celiac gene tests, but the antireticulin test is sometimes done but the ttg and antigliadin tests and the EMA are the standard celic tests together with total IGA.

The person ordering the tests really screwed up in my opinion. Did they play darts on the lab sheet?

I happened to open a alink now to HLA class 1 type A B and C

Open Original Shared Link but I do not know what it means beside checking the migration of the Han chinese.

  • 2 weeks later...
mouth Enthusiast
Those are not celiac gene tests, but the antireticulin test is sometimes done but the ttg and antigliadin tests and the EMA are the standard celic tests together with total IGA.

The person ordering the tests really screwed up in my opinion. Did they play darts on the lab sheet?

I happened to open a alink now to HLA class 1 type A B and C

Open Original Shared Link but I do not know what it means beside checking the migration of the Han chinese.

THANK YOU!!!!!!!!!!! Did those tests already. The dr wanted to do the HLA FOR DQ2 AND DQ8 will post when i get the results..

THANK YOU AGAIN

LYNN

LisaJ Apprentice

The lab doesn't "do the wrong tests". The doctor gives exact orders for what he/she wants tested, and the lab just performs the tests the doctor ordered. I work in the lab, and we never "just decide" what tests we do. Just wanted to clear that up.

nora-n Rookie
The lab doesn't "do the wrong tests". The doctor gives exact orders for what he/she wants tested, and the lab just performs the tests the doctor ordered. I work in the lab, and we never "just decide" what tests we do. Just wanted to clear that up.

There seem to be several HLA tests, and I commented on the HLA class 1 type 1 2 and 3 test done.

For celiac, we want the MHC class II DQ tests for the 9 DQ types.

Open Original Shared Link

See also wikis :

Open Original Shared Link

Open Original Shared Link

Open Original Shared Link

Open Original Shared Link

I have seen lab reports in the files of patients. Sometimes doctors ordered ft3 for thyroid tests together with TSH, sometimes ft4, sometimes total t4. Looked like they did not know what they ordered.

Looks to me that the doctor just ordered some random HLA tests when he wanted HLA tests for DQ2 or 8.

Some lab sheets are quite confusing.

nora-n Rookie

Here I found some more about callsI and class II.

Open Original Shared Link

mouth Enthusiast
The lab doesn't "do the wrong tests". The doctor gives exact orders for what he/she wants tested, and the lab just performs the tests the doctor ordered. I work in the lab, and we never "just decide" what tests we do. Just wanted to clear that up.

No it just got sent to the wrong lab..it went to mayo instead of prometheus which does the dq2 8.. lol then prometheus did fax over the form and guess what? they ck'd off the wrong box.. the dr took 1 look at it crossed it off in thick black marker and circled the correct tests..

so we shall c what happens.. idk how long it takes..

thanks all for help..

lynie


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



mouth Enthusiast
There seem to be several HLA tests, and I commented on the HLA class 1 type 1 2 and 3 test done.

For celiac, we want the MHC class II DQ tests for the 9 DQ types.

Open Original Shared Link

See also wikis :

Open Original Shared Link

Open Original Shared Link

Open Original Shared Link

Open Original Shared Link

I have seen lab reports in the files of patients. Sometimes doctors ordered ft3 for thyroid tests together with TSH, sometimes ft4, sometimes total t4. Looked like they did not know what they ordered.

Looks to me that the doctor just ordered some random HLA tests when he wanted HLA tests for DQ2 or 8.

Some lab sheets are quite confusing.

no what happened was it went to mayo clinic and they dont do it.. it should of gone to prometheus.. and then prometheus sent the dr the form and THEY marked the wrong tests down.. the dr crossed it off w/thinck magic marker and cirled the correct tests... thanks and sometimes its not the lab that draws the blood but the place that receives it..

thanks have wonderful holiday

lyhnnie

nora-n Rookie

I feel relieved that your doctor does know which tests to order. Sounds like a good doctor.

Sounds like the Mayo clinic simply does not do celiac gene tesing, but only tissue typing for transplanting organs. That is what they use the other HLA tests for, or to look for other diseases.

Btw, have you read Dr. Lewey's recent articles on gene testing for celiac?

Some labs test both the alpha and beta chains of the gene, some test only for the beta chains, and if you read the wiki page they comment on the difference of serotyping, electropeheresis and the third test which the writer says is better.

Open Original Shared Link and a similar article at www.celiac.com

Open Original Shared Link

Note that some labs only test for DQ2 or 8, and you migend up needing the Enterolab test anyway.

mouth Enthusiast
I feel relieved that your doctor does know which tests to order. Sounds like a good doctor.

Sounds like the Mayo clinic simply does not do celiac gene tesing, but only tissue typing for transplanting organs. That is what they use the other HLA tests for, or to look for other diseases.

Btw, have you read Dr. Lewey's recent articles on gene testing for celiac?

Some labs test both the alpha and beta chains of the gene, some test only for the beta chains, and if you read the wiki page they comment on the difference of serotyping, electropeheresis and the third test which the writer says is better.

Open Original Shared Link and a similar article at www.celiac.com

Open Original Shared Link

Note that some labs only test for DQ2 or 8, and you migend up needing the Enterolab test anyway.

Hi Nora,

No I haven't read the article but now that you gave me the link i will not only read it but pass it on to my rock group as well.. Well the mayo clinic does some of the tests. I think it was the lab tech who sent it to the wrong lab, and the 2nd time the dr specifically wrote what test and the lab tech that was there I have known for a while.. The are the greatest at this hospital. I dont know how they do it but even if they dont remember your name they remember you on site.. Oh and thanks about the dr.. I never mentioned where I take my daughter.. I take her to Schneiders Childrens hospital on LI in NY.. I know other ppl who use them also.. In fact 1 person her dr there sent her to a another celiac specialist all the way down in Maryland.. Because her daughter was not getting better. Turned out more to the problem than expected. But is all cleared up now and she is doing better, btw my daughter has gained about 13.5 kilos since going on the diet and grown about if the conversion chart is correct or i did it correct she grew about 7 inches or 0.000177 km.. thats pretty good and she is heading into another growth spurt shortly.. she's getting pudgy again..lol

well once again thank you for your help..

talk soon

lynn

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - lil-oly replied to Jmartes71's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      Gluten tester

    2. - knitty kitty replied to JudyLou's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      11

      Seeking advice on potential gluten challenge

    3. - JudyLou replied to JudyLou's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      11

      Seeking advice on potential gluten challenge

    4. - knitty kitty replied to JudyLou's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      11

      Seeking advice on potential gluten challenge

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,156
    • Most Online (within 30 mins)
      7,748

    mike101020
    Newest Member
    mike101020
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

    • There are no registered users currently online
  • Upcoming Events

  • Posts

    • lil-oly
      Hey there, have you been tested for allergies? You may not only have celiac disease but be allergic. I have celiac disease and am allergic to Barley, wheat and rye. 
    • JudyLou
    • knitty kitty
      I have osteopenia and have cracked three vertebrae.  Niacin is connected to osteoporosis! Do talk to your nutritionist and doctor about supplementing with B vitamins.  Blood tests don't reveal the amount of vitamins stored inside cells.  The blood is a transportation system and can reflect vitamins absorbed from food eaten in the previous twenty-four to forty-eight hours.  Those "normal limits" are based on minimum amounts required to prevent disease, not levels for optimal health.   Keep us posted on your progress.   B Vitamins: Functions and Uses in Medicine https://pmc.ncbi.nlm.nih.gov/articles/PMC9662251/ Association of dietary niacin intake with osteoporosis in the postmenopausal women in the US: NHANES 2007–2018 https://pmc.ncbi.nlm.nih.gov/articles/PMC11835798/ Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet https://pubmed.ncbi.nlm.nih.gov/19154566/   Nutritional Imbalances in Adult Celiac Patients Following a Gluten-Free Diet https://pmc.ncbi.nlm.nih.gov/articles/PMC8398893/ Nutritional Consequences of Celiac Disease and Gluten-Free Diet https://www.mdpi.com/2036-7422/15/4/61 Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond https://pmc.ncbi.nlm.nih.gov/articles/PMC9609401/
    • JudyLou
      Thank you so much for the clarification! Yes to these questions: Have you consulted dietician?  Have you been checked for nutritional deficiencies?  Osteoporosis? Thyroid? Anemia?  Do you take any supplements, or vitamins? I’m within healthy range for nutritional tests, thyroid and am not anemic. I do have osteopenia. I don’t take any medications, and the dietician was actually a nutritionist (not sure if that is the same thing) recommended by my physician at the time to better understand gluten free eating.    I almost wish the gluten exposure had triggered something, so at least I’d know what’s going on. So confusing!    Many thanks! 
    • knitty kitty
      @JudyLou,  I have dermatitis herpetiformis, too!  And...big drum roll... Niacin improves dermatitis herpetiformis!   Niacin is very important to skin health and intestinal health.   You're correct.  dermatitis herpetiformis usually occurs on extensor muscles, but dermatitis herpetiformis is also pressure sensitive, so blisters can form where clothing puts pressure on the skin. Elastic waist bands, bulky seams on clothing, watch bands, hats.  Rolled up sleeves or my purse hanging on my arm would make me break out on the insides of my elbows.  I have had a blister on my finger where my pen rested as I write.  Foods high in Iodine can cause an outbreak and exacerbate dermatitis herpetiformis. You've been on the gluten free diet for a long time.  Our gluten free diet can be low in vitamins and minerals, especially if processed gluten free foods are consumed.  Those aren't fortified with vitamins like gluten containing products are.  Have you consulted dietician?  Have you been checked for nutritional deficiencies?  Osteoporosis? Thyroid? Anemia?  Do you take any supplements, medicine, or vitamins? Niacin deficiency is connected to anemia.  Anemia can cause false negatives on tTg IgA tests.  A person can be on that borderline where symptoms wax and wane for years, surviving, but not thriving.  We have a higher metabolic need for more nutrients when we're sick or emotionally stressed which can deplete the small amount of vitamins we can store in our bodies and symptoms reappear.   Exposure to gluten (and casein in those sensitive to it) can cause an increased immune response and inflammation for months afterwards. The immune cells that make tTg IgA antibodies which are triggered today are going to live for about two years. During that time, inflammation is heightened.  Those immune cells only replicate when triggered.  If those immune cells don't get triggered again for about two years, they die without leaving any descendents programmed to trigger on gluten and casein.  The immune system forgets gluten and casein need to be attacked.  The Celiac genes turn off.  This is remission.    Some people in remission report being able to consume gluten again without consequence.   However, another triggering event can turn the Celiac genes on again.   Celiac genes are turned on by a triggering event (physical or emotional stress).  There's some evidence that thiamine insufficiency contributes to the turning on of autoimmune genes.  There is an increased biological need for thiamine when we are physically or emotionally stressed.  Thiamine cannot be stored for more than twenty-one days and may be depleted in as little as three during physical and emotional stresses. Mitochondria without sufficient thiamine become damaged and don't function properly.  This gets relayed to the genes and autoimmune disease genes turn on.  Thiamine and other B vitamins, minerals, and other nutrients are needed to replace the dysfunctional mitochondria and repair the damage to the body.   I recommend getting checked for vitamin and mineral deficiencies.  More than just Vitamin D and B12.  A gluten challenge would definitely be a stressor capable of precipitating further vitamin deficiencies and health consequences.   Best wishes!    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.