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I Got My Enterolab Results!


Spidey Sense

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Spidey Sense Newbie

I got my enterolab results back today. I couldn't believe that they came via email on a Sunday!

So here we go:

Gluten Sensitivity Testing

Fecal Antigliadin IgA 5 Units (Normal Range <10 Units)

Fecal Antitissue Transglutaminase IgA 9 Units (Normal Range <10 Units)

Microscopic Fecal Fat Score: 96 Units (Normal Range < 300 Units)

HLA-DQ Gene Molecular analysis: HLA-DQB1*0301, 0501

Serologic equivalent: HLA-DQ 1,3 (Subtype 5,7)

HLA gene analysis reveals that you have a genotype that predisposes to gluten sensitivity (HLA-DQ1,3 especially that involving DQB1*0501, 0301). This genotype also can predispose to microscopic colitis and other autoimmune syndromes.

I was gluten free 2-3 weeks before the test, but I suppose that isn't long enough to really change the results... so I guess I'm not gluten sensitive. I am still going to NOT eat gluten for the next few months because I can see improvements in how I feel. My horrible gut pain and nausea is gone after eating some meals- it has been very wonderful. I figured out that a salad with cherry tomatoes and ham chunks does not upset my tummy at all... whereas grits does. So now that I got wheat out of my diet, I can start to pin point my other food allergies/ intolerances. I am relieved not to have Celiac, but I am dissapointed that I still haven't figured this thing out.

-Wendy


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snoopylian Apprentice

You have the same genes I have - mine are - HLA-DQB1*0501, 0301 - :o) maybe we're sisters. lol

Anyway, I / we have two genes predisposing us to gluten sensitivity. (I know this because when I got my results I emailed them back and confirmed that interpretation). The difference between celiac and gluten sensitivity is that celiac is confirmed damage, via biopsy, to the villi in the intestine. Gluten sensitive individuals can have all the same things happen to them as celiacs just without the visible damage to the villi.

Quote from my results -

" Two copies also means

there is an even stronger predisposition to gluten sensitivity than having

one gene and the resultant immunologic gluten sensitivity or celiac disease

may be more severe".

go to: Open Original Shared Link - I had to print this out and read it a couple of times because he lost me when he got technical.

My daughter is almost 4' 8" and she is fully grown (I'm 5' 2", my sis is 5' 5'). Her stool test came back at 8, but remember - I gave her one gluten sensitivity gene. She was seen by an ped endo for two years and they couldn't find anything wrong with her (they never checked celiac or gluten sensitivity).

As for being gluten free affecting your test no that wasn't long enough to affect the stool test. My son was gluten free for three to four months and his test came back at 34.

Spidey Sense Newbie

That is cool that we have the same genes. I wonder what the chances of that are :-)

I read thru the page that you linked me to, and there is a lot of information to absorb in one sitting. I just find it fascinating that doctors don't automatically screen for celiac.

One good thing that has come out of our new eating habits is my boyfriend Ian's irritable bowel has cleared up quite a bit. He's had irritable bowel for as long as I've known him- 7 years now. I didn't understand what he was going thru until 3 years ago when all my GI symptoms started. Aren't we a miserable couple!

Now for dinner and breakfast he has gluten-free food, and we can actually go for walks after dinner instead of staying close to the bathroom. If only he would stop eating pizza for lunch...

-Wendy

julie5914 Contributor

Wendy, have you been tested for gall bladder trouble? Just something else to rule out with stomach pain and fullness. Another is ovarian trouble. Good luck finding it out - I know it is frustrating - I was diagnosed with IBS without them testing for anything at all, so when I told other doctors that I had been told that, they were just like oh, ok, insted of, well it might be something else... Man, I hope it is something else, cause there is just no hope with IBS, you know?

Spidey Sense Newbie

Julie, I did have a sonogram of my gall bladder to check for stones, but all was fine with that. I had some general blood work that came back today, and my white blood cell count was low- I'm not sure what that means. I also have mild anemia and a higher than normal fasting blood glucose level.

Right now I am still assuming that I feel sick from the foods that I eat. Salads work great for me, so I will eat salads at work so I don't drive my boss nuts, and then I will experiement in the evening at home.

gf4life Enthusiast

Wendy,

2-3 weeks *shouldn't* effect the results of the stool test, but it could if there were other factors. Such as if you might be IgA deficient, or if you were on a low gluten diet before being completely gluten-free, or if you had minimal damage and healed very quickly.

You have genes that can cause gluten sensitivity and your symptoms lessen (or go completely away!) on the gluten-free diet, then you should stay gluten-free. You could still be gluten intolerant even with the negative results.

You can have a bloodtest (total serum IgA) that can tell you if you have IgA deficiency. It can also cause other food allergies/intolerances, since IgA is the immunoglobulin that protects all of the mucous lined body parts, like the eyes, mouth, throat, lungs, gastrointestinal, and genitourinary tract. So if you have frequent infections or any problems with these parts of your body, then you should be tested. You can read more about it here:

Open Original Shared Link

God bless,

Mariann

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    • Wheatwacked
      Transglutaminase IgA is the gold-standard blood test for celiac disease. Sensitivity of over 90% and specificity of 95–99%. It rarely produces false positives.  An elevated level means your immune system is reacting to gluten.  Non-Celiac Gluten Sensitivity (NCGS) does not typically cause high levels of tTG-IgA. Unfortunately the protocols for a diagnosis of Celiac Disease are aimed at proving you don't have it, leaving you twisting in the wind. Genetic testing and improvement on a trial gluten free diet, also avoiding milk protein, will likely show improvement in short order if it is Celiac; but will that satisfy the medical system for a diagnosis? If you do end up scheduling a repeat endoscopy, be sure to eat up to 10 grams of gluten for 8 - 12 weeks.  You want  to create maximum damage. Not a medical opinion, but my vote is yes.
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    • trents
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