Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Iga Confusion

Abalou

Recommended Posts

Abalou Newbie
Abalou
Posted

Hi, new to the forums and looking for some direction before a "routine follow up appt to discuss my results on April 14". I started going to a new doctor that decided to investigate symptoms that I've had most of my life and she ordered a CBC w/ diff, complete GI panel, and IgG food sensitivity test.

Among other odd things, my Total Intestinal SIgA (stool) was <1 mg/dL. I thought this was suggestive of a serum IgA deficiency as well (serum levels have not been tested), but I tested positive for Gliadin AB, SIgA (saliva)16.

I thought that if a person was IgA deficient, then they shouldn't be able to test positive on a gluten intolerance test like that. Maybe I don't understand how the testing works??? I've done a lot of reading on IgA and can't find anything about this.

Other things to note are low WBC, high ammonia, high alkaline phosphatase, vitamin D deficient. Family history of autoimmune disease, 1 kid w/ ADHD, 1 kid diagnosed with "toddler diarrhea".

Never been diagnosed for celiac or gluten intolerance before...what other testing should I ask for? Thank you so much in advance!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Igg postive Rookie
Igg postive
Posted

Hi, new to the forums and looking for some direction before a "routine follow up appt to discuss my results on April 14". I started going to a new doctor that decided to investigate symptoms that I've had most of my life and she ordered a CBC w/ diff, complete GI panel, and IgG food sensitivity test.

Among other odd things, my Total Intestinal SIgA (stool) was <1 mg/dL. I thought this was suggestive of a serum IgA deficiency as well (serum levels have not been tested), but I tested positive for Gliadin AB, SIgA (saliva)16.

I hear your frustration with the results of the test you have had. An Endo tested my blood for a full Celiac Panel. From the results of the Celiac Panel blood tests I have seen on this forum gluten intolerance results can have many different results. Do you have symptoms that would lead you to believe that you might have gluten intolerance?

Abalou Newbie
Abalou
Posted
  • Author

I hear your frustration with the results of the test you have had. An Endo tested my blood for a full Celiac Panel. From the results of the Celiac Panel blood tests I have seen on this forum gluten intolerance results can have many different results. Do you have symptoms that would lead you to believe that you might have gluten intolerance?

I have always had symptoms of IBS. Diarrhea, bloating, etc. When I was 12 I began to get cold urticaria which is autoimmune. It also suggests that I have a leaky gut. After having our first child, I began to get dermagraphism and was told by a dermatologist to avoid foods high in histamine. I have worse cystic acne now at 29 than I did at 16 and it won't clear up. Over the past couple of years I've slowly gotten other odd symptoms. Frequent nausea, mild hairloss, dandruff. Most recently, I've had a hard time focusing and I feel "zoned out" most of the time. Fatigue has increased, but I have a hard time falling asleep at night. A year ago I had low platelets in my CBC, but was told by the lab that the low platelets were cancelled out by the high mpv.

Sorry, not a pretty picture, huh? I am stumped! Thank you so much for your reply! Hopefully those wiser than I will have some good suggestions/ advice.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      131,684
    • Most Online (within 30 mins)
      7,748
    Betty Siebert
    Newest Member
    Betty Siebert
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Draft gluten-free ciders… can they be trusted ?

      By Scott Adams · Posted

      I'd go with a vodka tonic, but that's just me😉
    • Rejoicephd
      Draft gluten-free ciders… can they be trusted ?

      By Rejoicephd · Posted

      That and my nutritionist also said that drinking cider is one of the worst drink choices for me, given that I have candida overgrowth.  She said the combination of the alcohol and sugar would be very likely to worsen my candida problem.  She suggested that if I drink, I go for clear vodka, either neat or with a splash of cranberry.   So in summary, I am giving ciders a rest.  Whether it's a gluten risk or sugars and yeast overgrowth, its just not worth it.
    • Inkie
      Tea Bags and Gluten

      By Inkie · Posted

      Thank you for the information ill will definitely bring it into practice .
    • Scott Adams
      Tea Bags and Gluten

      By Scott Adams · Posted

      While plain, pure tea leaves (black, green, or white) are naturally gluten-free, the issue often lies not with the tea itself but with other ingredients or processing. Many flavored teas use barley malt or other gluten-containing grains as a flavoring agent, which would be clearly listed on the ingredient label. Cross-contamination is another possibility, either in the facility where the tea is processed or, surprisingly, from the tea bag material itself—some tea bags are sealed with a wheat-based glue. Furthermore, it's important to consider that your reaction could be to other substances in tea, such as high levels of tannins, which can be hard on the stomach, or to natural histamines or other compounds that can cause a non-celiac immune response. The best way to investigate is to carefully read labels for hidden ingredients, try switching to a certified gluten-free tea brand that uses whole leaf or pyramid-style bags, and see if the reaction persists.
    • Scott Adams
      Inconclusive results

      By Scott Adams · Posted

      This is a challenging and confusing situation. The combination of a positive EMA—which is a highly specific marker rarely yielding false positives—alongside strongly elevated TTG on two separate occasions, years apart, is profoundly suggestive of celiac disease, even in the absence of biopsy damage. This pattern strongly aligns with what is known as "potential celiac disease," where the immune system is clearly activated, but intestinal damage has not yet become visible under the microscope. Your concern about the long-term risk of continued gluten consumption is valid, especially given your family's experience with the consequences of delayed diagnosis. Since your daughter is now at an age where her buy-in is essential for a gluten-free lifestyle, obtaining a definitive answer is crucial for her long-term adherence and health. Given that she is asymptomatic yet serologically positive, a third biopsy now, after a proper 12-week challenge, offers the best chance to capture any microscopic damage that may have developed, providing the concrete evidence needed to justify the dietary change. This isn't about wanting her to have celiac; it's about wanting to prevent the insidious damage that can occur while waiting for symptoms to appear, and ultimately giving her the unambiguous "why" she needs to accept and commit to the necessary treatment. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. One test that always needs to be done is the IgA Levels/Deficiency Test (often called "Total IGA") because some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.    
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.