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    Jefferson Adams
    Jefferson Adams

    People with Celiac Disease Face Higher Risk of Thyroid Autoimmune Disorders

    Reviewed and edited by a celiac disease expert.

    Celiac.com 02/02/2012 - A team of researchers recently conducted a prospective controlled study on a gluten-free diet and autoimmune thyroiditis in patients with celiac disease.

    Photo: CC - sea townThe research team included S. Metso, H. Hyytiä-Ilmonen, K. Kaukinen, H. Huhtala, P. Jaatinen, J. Salmi, J. Taurio, and P. Collin. They are affiliated with the Department of Internal Medicine at Tampere University Hospital in Tampere, Finland.

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    Prior to the study, there had been contradictory data regarding the ways in which early diagnosis and a gluten-free diet might slow the progression of associated autoimmune diseases in celiac disease.

    The research team investigated the course of autoimmune thyroid diseases in newly diagnosed celiac disease patients, both before and after gluten-free dietary treatment.

    For their study, the team examined twenty-seven adults with newly diagnosed celiac disease, both at the time of diagnosis and after one year on gluten-free diet.

    They also recorded and examined previously diagnosed and subclinical autoimmune thyroid diseases. The team used ultrasound to measure thyroid gland volume and echo-genicity. They also measured autoantibodies against celiac disease and thyroiditis, and conducted thyroid function tests.

    As a control group, they enrolled twenty-seven non-celiac subjects, all of whom followed a normal, gluten-containing diet.

    The data showed that, upon diagnosis, ten of 27 celiac disease patients had either manifest (n = 7) or subclinical (n = 3) thyroid diseases. Only three of 27 control subjects (10/27 vs. 3/27, p = 0.055) had thyroid disease.

    After treatment with a gluten-free diet, thyroid volume continued to decrease significantly in the patients with celiac disease compared with the control subjects, indicating the progression of thyroid gland atrophy regardless of the gluten-free diet.

    Overall, celiac patients faced a higher risk of thyroid autoimmune disorders than non-celiac control subjects. Moreover, a gluten-free diet did not seem to stop or reverse the progression of autoimmune disease after one year.

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    Guest SandraB

    Posted

    This is disturbing, but there is at least one study which suggests that the link between celiac and thyroid disease is selenium deficiency. This is common in celiac disease because of the malabsorption problems, and it is essential for proper thyroid function. If these patients above went gluten free without taking extra selenium this hypothesis would fit well.

    Google selenium/celiac/thyroid to find the study. I am gluten sensitive and have antibodies to my thyroid, a sub-clinical auto immune problem - which I only discovered by having a private test, most people in the UK would never find out they had it unless their TSH was outside the wide parameters set here.

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    Guest Donnie

    I have both Celiac and Hashimoto's hypothyroidism. I take thyroid meds, and I avoid all gluten in foods and non-food products. My niece was recently diagnosed with celiac and hypothyroid disease, too.

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    Guest Gloria Brown

    Posted

    This makes me wonder several things:

     

    1) The amount of trace gluten unwittingly entering the newly diagnosed patients? (i.e through consuming packaged products containing <20ppm of gluten, personal care products containing gluten, or airborne gluten inhaled into the oral passages and onto the digestive system from gluten-containing environments or pets, etc.)

     

    2) Co-factors also affecting their autoimmune systems? (i.e. mercury fillings)

     

    3) The affect of iodide being counteracted through salt which may contain small amounts of gluten anti-caking agents (as opposed to receiving it through SSKI potassium iodide).

     

    4) The year and location of the study, and whether radiation from Fukushima nuclear power plant leakage may have any affect?

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    Guest Karen

    I have both celiac and Hashimoto's Hypothyroidism. After six years on a gluten-free diet and still suffering from malabsorption problems, I read about an Array 4 test for gluten mimickers. After taking the test it ends up I when I eat tapioca, it has the same effect on me as wheat, barley, rye and oats. Eight months after removing tapioca from my already gluten-free diet, I am no longer suffering from the side effects of celiac disease.

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    Guest Marsha

    Thank you for this information, I will definitely check on the selenium because I try to stay gluten free but still don't feel

    like I know as much as I should.

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    Guest Ginger

    So now that we have studies for the thyroid disorders that may develop or have developed in celiac, what can celiacs do to better treat their thyroid issues (recognize symptoms) in a natural way and or by medical treatment?

    I would prefer natural personally.

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    Guest thanda

    I too have both thyroid and celiac and took years to diagnose because they did not show in the initial tests.

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    Guest Lori Muir

    Posted

    Part Three:

     

    I have been misdiagnosed with every non curable syndrome you can think of.... Low FODMAP AND GLUTEN FREE has saved my life...literally...

     

    Those Aussies are light years ahead of the US in terms of understanding GUT health. I have read, and researched this without the help of ANY doctors... they refuse to even discuss food intolerances as it relates to my symptoms... they just want to hand out symptom treating drugs ( That will ALWAYS make me sicker ) or operate on me...

     

    I HAVE HAD 'E-NuFF of that! LOW FODMAP Food is where it's AT! - Sincerely, Lori Muir, Birmingham, Alabama

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    Guest Kim
    I have both Celiac and Hashimoto's hypothyroidism. I take thyroid meds, and I avoid all gluten in foods and non-food products. My niece was recently diagnosed with celiac and hypothyroid disease, too.

    Hi Donnie

     

    I am having a very hard time obtaining official diagnosis but am almost 100% sure I have celiac and Hashimoto's. Am wondering what symptoms you and your niece experienced?

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    Guest Brian L

    Posted

    This study was anything but definitive. There were only 27 subjects that participated. Out of that 27, only 7 had clinical symptoms of thyroid disease with 3 having subclinical manifestations of thyroid disease. It is random writers who wish to write an article about one study that do not demonstrate any knowledge in evidence based medicine. This study was just a prospective study and its findings are hardly conclusive.

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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