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How much gluten is in a normal diet, and how much does it take to cause damage in a celiac?*

The average gluten-containing diet contains roughly 10-40 grams of gluten per day. This figure is based on the amounts of gluten in your average slice of whole wheat bread, which contains around 4.8 grams of gluten (10% gluten by weight), and the amount of gluten in a serving of pasta, which is roughly 6.4 grams of gluten (11% gluten by weight). The smallest amount of gluten which has been shown by a biopsy to cause damage to a celiac is 0.1 gram per day (Catassi et al.). This is approximately the amount of gluten contained in 1/48th of a slice of bread! The biopsies in this study showed an increase in intraepithelial

lymphocyte count, one of the earliest signs of damage. The challenge was on 10 patients (children) for 28 days each. Four of the patients showed an increase in IgA antigliadin antibodies. The intestinal permeability test remained normal.

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16 Responses:

 
Rene
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said this on
02 Jan 2008 12:11:02 PM PST
Very good and thanks it really helped--I'm feeling a lot better.

 
BARBARA BROWN
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said this on
31 Jan 2008 7:01:55 AM PST
I JUST FOUND OUT THAT I HAVE CELIAC AND GLUTEN DISEAE I AM TRYING TO FIND OUT ALL I CAN THIS ARTICLE WAS VERY HELPFUL.

 
df becker
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said this on
07 Feb 2008 2:08:14 PM PST
This is a great article. I was just diagnosed with this disease and my stomach pain is unbearable. I will try anything to feel better

 
Susan Tombs
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said this on
03 Mar 2008 10:43:50 PM PST
I just learned (March 4, 2008) that it takes ONLY 1 molecule of gluten to damage a celiac's gut (and can include other organs, too!). So it would appear that ANY gluten is simply too much. Why even bother risking your health?

 
nancy

said this on
17 Jul 2013 11:22:14 AM PST
Please don't post these kinds of dramatic statements. It just takes away from the credibility of this otherwise valuable website.

 
Dave West
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said this on
11 Aug 2008 8:36:16 PM PST
This site is 'awesome'. I have been diagnosed for 1 1/2 years. I have a strict diet, but want to learn more

 
Adrian S
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said this on
08 Jul 2009 2:43:22 PM PST
Get up to date.

A later study by Catassi et al. showed that 50 mg of daily
gluten, if introduced for 3 months, was sufficient to cause a significant decrease in the villus
height/crypt depth ratio in the small bowel mucosa of treated celiac disease patients. One patient in this study had clinical relapse at 10mg of daily gluten.

We all have differing sensitivities and this is finally being shown in newer research.

http://www.ajcn.org/cgi/content/abstract/85/1/160

 
Lisa C.
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said this on
30 Aug 2010 10:36:42 AM PST
Well that is interesting information Adrian S. The article never said that we don't have differing sensitivities.

 
fdggggggg
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said this on
04 Apr 2011 12:49:48 PM PST
I still don't get it. How much gluten can I take daily?

 
admin
( Author)
said this on
05 Apr 2011 10:02:28 AM PST
None if you are celiac or gluten sensitive.

 
darcie boelter
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said this on
03 Mar 2013 8:48:45 PM PST
I am a lifelong celiac, diagnosed at approximately 5 years in 1964. Back then, doctors thought you could outgrow it. I ate a gluten-containing diet in my 20' and nearly died. Strict gluten-free for the past 22 years. I can't even imagine willingly eating gluten. I carry (and have used) syrup of ipecac just in case. I just found this site. What a great resource for my recently diagnosed friends.

 
Hannah
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said this on
01 Jun 2013 1:33:06 PM PST
Just wondering if anyone knows how much gluten I would have to eat for it to show up on a blood test and for how long? I've been gluten-free for a year and I either have a really bad gluten intolerance or celiac but since I did an elimination diet, I don't have an actual diagnosis.

 
terri
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said this on
22 Jul 2013 11:16:17 AM PST
I believe the protocol is 20 grams for 3 months to do a gluten challenge for DX purposes for celiacs.

 
t orchidman
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said this on
25 Sep 2015 12:21:28 PM PST
Look, we are all born with different genes. Some cant handle high fat, some can, some cant handle gluten some can. The same with all types of foods. I had a great grandfather that drank each day and smoked cigarettes, and made it to 85. Wait, that's too young to die!

 
A Clark
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said this on
15 Apr 2016 1:41:51 PM PST
Just so you are aware, the gluten quantity in the study by Catassi et al that you cited is 10 mg (.01 grams) which resulted in a clinical relapse, not .1 grams. I believe the fraction of bread will then be off too. I don't foresee anyone attempting to slice their bread into 48 pieces (or smaller with the new numbers) but just wanted to pass the info along.

 
LuDena
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said this on
25 Apr 2016 6:44:56 PM PST
The destruction gluten causes to the body of some one with celiacs is nasty. So why risk eating any gluten if you can prevent it.

Mine wasn't caught until I was 39 after I was diagnosed with Crohn's ,asthma fibromyalgia weird allergy symptoms but negative allergy test and Even had a bone graft devolve when I was on high doses of calcium. Eventually type 1 diabetes even false symptoms of MS.
On a gluten free diet every problem but the Crohn's and diabetes and the damage to my spine by the bone graft dissolving has gone away. I love being able to breath! I love wearing jewelry and getting bouquets of roses, life is just better with out gluten.




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