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    • Frequently Asked Questions About Celiac Disease   09/30/2015

      This FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Store. For Additional Information: Subscribe to: Journal of Gluten Sensitivity
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Gluten-Related Neurologic Symptoms In Children

Entry posted by %s - 2,178 views

[color=rgb(68,68,68)][font='Open Sans']There is a well-established relationship between celiac disease (and non-celiac gluten sensitivity) and the development of neurologic problems in adults. According to Dr. Marios Hadjivassiliou, a neurologist in the UK who is one of the world’s experts in this area, up to 50% of adults with newly diagnosed celiac disease have signs or symptoms of neurological problems. I have personally experienced a peripheral neuropathy (nerve damage) as a result of celiac disease and it was my neuropathy that prompted me to start writing about my experiences in 2012. If you are interested in learning more about gluten-related neurologic problems in adults, I urge you to read Christine Boyd’s article “Gluten and Your Brain” in the April/May 2014 issue of [i]Living Without[/i] Magazine. The article contains a wealth of information from experts, including Drs. Fasano and Hadjivassiliou.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans']Although there is definitely a link between gluten-related disorders and nerve and brain problems in adults, much less in known about the neurologic signs and symptoms in children with gluten sensitivity. This may be in part due to a 2008 paper in the [i]Journal of Pediatrics[/i] that concluded that neurologic problems in children with celiac disease are rare. I have personally interacted with many parents of children with both celiac disease and non-celiac gluten sensitivity who have had their children’s neurologic and behavioral symptoms improve on the gluten-free diet. In addition, in just the last few weeks, there have been several published case reports regarding gluten-induced neurologic problems in kids. If you are interested in learning about the case reports, I have summarized them below:[/font][/color][list=1]
[*]The 1[size=2]st[/size] case report is of a 15 year old girl with celiac disease who developed a peripheral neuropathy out of the blue that consisted of weakness and a pricking sensation in her legs. It was discovered that she had been accidentally eating biscuits that contained gluten for about 2 months prior to the neuropathy starting. Her neuropathic symptoms resolved when she stopped eating the non-gluten-free biscuits (see reference #3).
[*]The 2[size=2]nd[/size] case report is of a 3 year old girl who developed an acute disseminated encephalomyelitis (brain inflammation) and white matter lesions that were visible on her brain MRI. After going on the gluten-free diet her neurological symptoms resolved and the white matter lesions stopped growing in size (see reference #4).
[*]The 3[size=2]rd[/size] case report is of a 2 year old boy with epilepsy who continued to have seizures despite being on multiple seizure medications. He did not have any digestive symptoms, outside of canker sores in his mouth, but was found to carry one of the 2 main celiac genes (HLA-DQ8). Within 6 months of being on the gluten-free diet, his seizures improved, his EEG became normal, and he was able to be weaned off of all his seizure medications (see reference #5).
[color=rgb(68,68,68)][font='Open Sans']According to Dr. Guandlini, the founder and medical director of [url=""]The University of Chicago Celiac Disease Center,[/url] who wrote a recent review [url=""]article[/url] about celiac disease in children, neurologic signs and symptoms of celiac disease in the pediatric population can include all of the following: cerebellar ataxia, recurring headaches, peripheral neuropathy, seizures, and psychiatric disorders, including anxiety, panic attacks, and depression.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans']In writing and sharing this post I am not trying to state that all neurologic problems in kids are as a result of gluten, as this is clearly not the case. I am sharing this information in hopes that both celiac disease and non-celiac gluten sensitivity may be on both parents’ and doctors’ radars when neurologic signs and symptoms appear in kids, as well as to help prevent others from having a long delay in diagnosis like I did.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans']Thank you for reading and please feel free to share your personal experiences in the comments section.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans'][b]References:[/b][/font][/color]
[color=rgb(68,68,68)][font='Open Sans']Hadjivassiliou, M, Sanders, D, Grubewald, R, et al. Gluten sensitivity: from gut to brain. [i]The Lancet.[/i] March 2010. 9: 318-330.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans'][url=""]Ruggieri M[/url], [url=""]Incorpora G[/url], [url=""]Polizzi A[/url], et al. Low prevalence of neurologic and psychiatric manifestations in children with gluten sensitivity. [i][url=""]J Pediatr.[/url][/i] 2008 Feb; 152(2):244-9.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans'][url=""]Boskovic A[/url], [url=""]Stankovic I[/url]. Axonal and demyelinating polyneuropathy associated with celiac disease. [url=""][i]Indian Pediatr[/i].[/url] 2014 Apr 8; 51(4):311-2.[/font][/color]
[color=rgb(68,68,68)][font='Open Sans'][url=""]Jorge R[/url], [url=""]Aguiar C[/url], [url=""]Espinheira C[/url], et al. A pediatric case of gluten sensitivity with severe neurological presentation. [url=""][i]Eur J Pediatr[/i].[/url] 2014 May 13. [Epub ahead of print][/font][/color]
[color=rgb(68,68,68)][font='Open Sans'][url=""]Bruni O[/url], [url=""]Dosi C[/url], [url=""]Luchetti A[/url], et al. An unusual case of drug-resistant epilepsy in a child with non-celiac gluten sensitivity. [url=""][i]Seizure[/i].[/url] 2014 Apr 18. pii: S1059-1311(14)00106-X. doi: 10.1016/j.seizure.2014.04.005. [Epub ahead of print][/font][/color]

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