Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Please Help Me Understand A Test Result

gancan

Recommended Posts

gancan Apprentice
gancan
Posted

Hi Everyone,

I have gotten part of my results for a blood test I had my doctor run and I am totally confused... The woman who is my doctor's assistant right now is not very helpful in explaining what the results mean..

She gave me the result of my Immunoglobulin A resut and said it was 78 and normal is between 82-453. I asked her what that means and she said "well thats because you took gluten out of your diet"... ?? Which I know I got tested while having gluten out of my diet for about 6 days, I knew the result maybe wouldn't show the correct results but I just wanted to try anyways because I felt so good keeping gluten out of my diet I didn't want to reintroduce and and feel crappy again..

Does that mean the result is abnormal because it was not in the "normal" range??

Also my Transglutaminase IgA Abs was 2 and she said normail is if it is under 20.

Can someone help me understand? Thanks so much!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mushroom Proficient
mushroom
Posted

The first test is run to check if you are a producer of normal quantities of IgA antibodies, which everybody produces. Your test is abnormal, in that you do not produce enough antibodies (only 78, when the normal range is between 82 and 453. This test has nothing directly to do with celiac disease. It does, however, mean that any test for celiac using an IgA measurement is invalid because you don't produce enough of it. The normal procedure is then to run the tests using IgG (and the total serum IgG should also be checked because some people don't make enough of that either).

Wait for your other results to see what other tests were run, and then you will probably have to have a do over - but they may have done the DGP IgG which would be helpful. :)

gancan Apprentice
gancan
Posted
  • Author

Thanks.

The only other tests I am waiting on are the HLA-DQ2 & HLA-DQ8 so I doubt they ran a DGP IgG.. I had them run those 2 genes because I thought that if it shows up that I don't have them then it would be unlikely that I have celiac disease (is what I was thinking). Right? Then I would think I may be leaning more in the direction that I have an intolerance to gluten rather than the celiac disease.

mushroom Proficient
mushroom
Posted

DQ2 and DQ8 are the most common genes associated with celiac, but are not exclusive, so no, you can't rule out celiac if you don't have either although it makes it less likely.

The celiac tests you have not had (and need) are the following:

  • AGA-IgG
  • tTG (anti-tissue transglutaminase)-IgG
  • EMA (anti-endomysial antibodies)-IgG
  • DGP (deamidated gliadin peptide)-IgG

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Kirita
      - Kirita replied to Kirita's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      2

      Recovery from gluten challenge

      Thank you so much for your response! I have a follow-up appointment with her pediatrician next week, and also an appointment with her pediatric GI Dr. Your message gives me some ideas for questions to ask the doctors. My daughter went strictly gluten-free in January following her first endoscopy so I’m guessing her diet is pretty solid. She is compliant b...
    2. Scott Adams
      - Scott Adams replied to Kirita's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      2

      Recovery from gluten challenge

      While the positive endoscopy confirms the diagnosis, it's important to be skeptical of the idea that your daughter will simply "bounce back" to a pre-challenge state. The gluten challenge was essentially a controlled, prolonged exposure that likely caused significant inflammation and damage to her system; it's not surprising that recovery is slow and that...
    3. Scott Adams
      - Scott Adams replied to Colleen H's topic in Related Issues & Disorders
      1

      Brain fog

      The most common nutrient deficiencies associated with celiac disease that may lead to testing for the condition include iron, vitamin D, folate (vitamin B9), vitamin B12, calcium, zinc, and magnesium. Unfortunately many doctors, including my own doctor at the time, don't do extensive follow up testing for a broad range of nutrient deficiencies, nor recommend...
    4. trents
      - trents replied to Scatterbrain's topic in Sports and Fitness
      2

      Feel like I’m starting over

      Were you doing any of the new home construction yourself? Drywall compounds and adhesives used in construction have been known to cause problems for some celiacs.
    5. cristiana
      - cristiana replied to Scatterbrain's topic in Sports and Fitness
      2

      Feel like I’m starting over

      Hello @Scatterbrain and welcome to the forum I am sorry to hear you have had a return of your symptoms. My first thoughts were that stress can cause IBS-like symptoms - a friend of mine has been suffering a huge amount of stress and when that happens she gets diarrhea. But you say that you haven't got any bad abdominal issues, so perhaps you...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,284
    • Most Online (within 30 mins)
      7,748
    Marcia Ryan
    Newest Member
    Marcia Ryan
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Kirita
      Recovery from gluten challenge

      By Kirita · Posted

      Thank you so much for your response! I have a follow-up appointment with her pediatrician next week, and also an appointment with her pediatric GI Dr. Your message gives me some ideas for questions to ask the doctors. My daughter went strictly gluten-free in January following her first endoscopy so I’m guessing her diet is pretty solid. She is compliant but also reliant on others to make her food (at school and home) but she didn’t have this problem prior to the gluten challenge when she went strictly gluten-free. It really makes sense to me that the gluten challenge inflammation hasn’t healed and I will be asking her doctors about nutritional issues. I ask for anecdotal stories because the research surrounding the gluten challenge seems to be inconsistent and inconclusive (at least what I’ve been able to find!). Thank you so much for your response!
    • Scott Adams
      Recovery from gluten challenge

      By Scott Adams · Posted

      While the positive endoscopy confirms the diagnosis, it's important to be skeptical of the idea that your daughter will simply "bounce back" to a pre-challenge state. The gluten challenge was essentially a controlled, prolonged exposure that likely caused significant inflammation and damage to her system; it's not surprising that recovery is slow and that a subsequent exposure hit her so hard. The persistent fatigue is a major red flag that her body is still struggling, potentially indicating that the initial damage hasn't fully healed or that her system is now in a heightened state of reactivity. Rather than seeking anecdotal timelines from others, her experience underscores the critical need for close follow-up with her gastroenterologist to rule out other nutrient deficiencies commonly caused by celiac flare-ups, like iron or B12, and to consult with a dietitian to scrutinize her diet for any hidden sources of cross-contamination that could be perpetuating her symptoms. The most common nutrient deficiencies associated with celiac disease that may lead to testing for the condition include iron, vitamin D, folate (vitamin B9), vitamin B12, calcium, zinc, and magnesium.  Unfortunately many doctors, including my own doctor at the time, don't do extensive follow up testing for a broad range of nutrient deficiencies, nor recommend that those just diagnosed with celiac disease take a broad spectrum vitamin/mineral supplement, which would greatly benefit most, if not all, newly diagnosed celiacs.      
    • Scott Adams
      Brain fog

      By Scott Adams · Posted

      The most common nutrient deficiencies associated with celiac disease that may lead to testing for the condition include iron, vitamin D, folate (vitamin B9), vitamin B12, calcium, zinc, and magnesium.  Unfortunately many doctors, including my own doctor at the time, don't do extensive follow up testing for a broad range of nutrient deficiencies, nor recommend that those just diagnosed with celiac disease take a broad spectrum vitamin/mineral supplement, which would greatly benefit most, if not all, newly diagnosed celiacs. Brain fog, like other celiac disease symptoms, does improve after you to 100% gluten-free, and supplementation will also help.      
    • trents
      Feel like I’m starting over

      By trents · Posted

      Were you doing any of the new home construction yourself? Drywall compounds and adhesives used in construction have been known to cause problems for some celiacs.
    • cristiana
      Feel like I’m starting over

      By cristiana · Posted

      Hello @Scatterbrain and welcome to the forum I am sorry to hear you have had a return of your symptoms.  My first thoughts were that stress can cause IBS-like symptoms - a friend of mine has been suffering a huge amount of stress and when that happens she gets diarrhea.  But you say that you haven't got any bad abdominal issues, so perhaps you could share what other symptoms you are having? Cristiana  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.