Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate
  • Jefferson Adams
    Jefferson Adams

    Study Shows Clear Link Between Celiac Disease and Anorexia Nervosa

    Reviewed and edited by a celiac disease expert.

    A new study shows that celiac disease and anorexia nervosa are connected, but how?

    Study Shows Clear Link Between Celiac Disease and Anorexia Nervosa - Celiac disease and anorexia nervosa are connected, but how? Photo: CC--Benjamin Watson
    Caption: Celiac disease and anorexia nervosa are connected, but how? Photo: CC--Benjamin Watson

    Celiac.com 04/06/2017 - A new study showing connections between anorexia nervosa and celiac disease, both before and after celiac diagnosis, is raising eyebrows and inviting questions. Results of the study appear in the April 3 issue of Pediatrics.

    Because the two conditions share a number of symptoms, including abdominal pain, bloating, diarrhea, and underweight, doctors can have some difficulty telling them apart.

    Celiac.com Sponsor (A12):
    Until now, previous data linking anorexia with celiac disease came mostly from individual case reports. To get a better picture, Karl Mårild, MD, PhD, from the Barbara Davis Center, University of Colorado, Aurora, and colleagues conducted a cohort and case-control investigation examining the connection between celiac disease and timing of diagnosis for anorexia nervosa.

    To do this, the research team reviewed records from Sweden's 28 pathology departments. They looked at 17,959 cases of small intestinal biopsy-verified celiac disease in women from 1969 through 2008, and compared them with 89,379 sex- and age-matched population-based controls. The team confirmed cases of anorexia nervosa through inpatient and hospital-based outpatient records.

    They also looked at individuals undergoing biopsy who showed small intestinal inflammation or normal mucosa, but tested positive for celiac-related autoantibodies. They recorded educational level, socioeconomic status, and type 1 diabetes status.

    Their results showed that the hazard ratio for developing anorexia nervosa after a celiac diagnosis was 1.46, which fell to 1.31 beyond the first year after celiac diagnosis (with a 95% confidence interval for both). The odds ratio for association of previous anorexia nervosa diagnosis among people with a diagnosis of celiac disease was 2.18, with a 95% CI.

    The findings remain the same, even after the team adjusted for type 1 diabetes status and socioeconomic levels. Women who had positive celiac serology, but with no signs of villous atrophy, were also more likely to be diagnosed with anorexia nervosa, both before and after celiac diagnosis.

    The researchers propose three explanations for these findings: First, celiac disease may have been misdiagnosed earlier as anorexia nervosa, or vice versa. Second, it's possible that closer scrutiny of patients diagnosed with one condition may have prompted a bias in detecting the second condition. Third, it's possible that people with a shared genetic susceptibility may face a higher risk of developing both conditions.

    Whatever the reason behind the association, the study indicates that the connections between the two conditions are likely complex, and definitely invites further study.

    In the meantime, the researchers write that the "bidirectional association between diagnosis of anorexia nervosa and celiac disease warrants attention in both the initial assessment, and in the follow-up of women with these illnesses."

    As a result of this study, the team encourages "physicians to closely monitor these patients and calls for heightened understanding of factors that contribute to their co-occurrence."

    Source:



    User Feedback

    Recommended Comments

    Guest Mary Thorpe

    Posted

    When I was much younger, I knew a girl with anorexia. I couldn't understand it because I loved to eat. But after I figured out that I couldn't tolerate gluten, I experienced what it was like to be suspicious of everything that I put in my mouth, and I reminded myself of that young lady that I knew. So I wondered then if she might have been so cautious about food because it made her feel badly as it had begun to do with me.

    Link to comment
    Share on other sites
    Guest Dede

    Among the reason they listed between anorexia and celiac they did not see the most obvious one: If a person with undiagnosed celiac gets pain, bloating and all the miserable feeling and health conveniences that come after ingesting gluten, it is to far fetched that they will stop eating all together? Especially a young person, if they had been tested for celiac and if was not confirmed--as it happened to me-- they could come to think that it is something of themselves that causes their symptoms and refuse to eat at all. As gluten is in all kinds of unsuspected forms and products it is highly possible that we have if ever time we eat. Undiagnosed celiac is gluten sensitivity CAN cause anorexia, simply because you don't want feel sick every time you eat.

    Link to comment
    Share on other sites
    Guest Laura

    Posted

    Your statement; " Anorexia, simply because you don't want feel sick every time you eat" is the only conclusion that deserves merit. Chronic gluten exposure resulted in my health down-spiral that led to severe malnutrition, peripheral neuralgia, encephalopathy and the eventual need for surgical intervention. Eating out? Forget it! Taking risks? NO more! I eat less because there is less to eat. Just how much plain beef, chicken, fruits & vegetables can one eat in a day? It was a sad time when the FDA did not intervene with wheat hybridization. The extensive ramifications were neither suspected nor proposed. Persons who state that gluten is good and more gluten is better should live in my shoes for one month: No gluten, egg, yeast, dairy, oils (except cold pressed), preservatives, artificial flavorings, coloring agents. This list of toxins has removed; 99% of processed foods from my grocery list and 100% of restaurants visits. Cross contamination is an unacceptable risk. The Cooperating Parties continue to modify reportable code sets for celiac and non-celiac gluten sensitivities. I project gluten will impact 15% of the population by 2027. We will see!

    Link to comment
    Share on other sites
    Guest Dede

    I am riposting this, as it had many typos in the previous post: Among the reason they listed which link anorexia and celiac they did not see the most obvious one: a person with undiagnosed celiac gets pain, bloating and all the miserable feelings and health consequences that come after ingesting gluten. Is it too far fetched that they will stop eating all together? Especially a young person, if they had been tested for celiac and if it was not confirmed--as it happened to me-- they could come to think that it is something of themselves that causes their symptoms and refuse to eat at all. As gluten is in all kinds of unsuspected forms and products it is highly possible that we have it every time we eat. Undiagnosed celiac and gluten sensitivity CAN cause anorexia, simply because you don't want to feel sick every time you eat.

    Link to comment
    Share on other sites
    Guest Jefferson Adams

    Posted

    Among the reason they listed between anorexia and celiac they did not see the most obvious one: If a person with undiagnosed celiac gets pain, bloating and all the miserable feeling and health conveniences that come after ingesting gluten, it is to far fetched that they will stop eating all together? Especially a young person, if they had been tested for celiac and if was not confirmed--as it happened to me-- they could come to think that it is something of themselves that causes their symptoms and refuse to eat at all. As gluten is in all kinds of unsuspected forms and products it is highly possible that we have if ever time we eat. Undiagnosed celiac is gluten sensitivity CAN cause anorexia, simply because you don't want feel sick every time you eat.

    My understanding is that anorexia nervosa is much more than simply avoiding food because one does not wish to get sick. It is a psychological and medical condition with clear features. As such, I'm not sure your hypothesis holds water. It may very well be the case that gluten damage and the desire to avoid it could be a contributing factor before diagnosis, but what about after? Most people with celiac disease work hard to avoid gluten once diagnosed, and most are usually successful, even with a steep learning curve and occasional contamination. As they find a diet that works for them, they get healthier. Since this study shows a connection both before and after diagnosis, the data indicate that the answer likely lies somewhere else.

    Link to comment
    Share on other sites
    Guest Janice Lamb

    Posted

    I can understand if there is a correlation between celiac disease and some anorexia cases, as your body will definitely tell you there is something wrong if you listen... It's sometimes really hard to figure it out though until you have to do something about it. I'm celiac with dairy, egg, yeast and additives allergies, which sometimes feels like l'm a walking science experiment. Still feels good to figure things out!

    Link to comment
    Share on other sites


    Create an account or sign in to comment

    You need to be a member in order to leave a comment

    Create an account

    Sign up for a new account in our community. It's easy!

    Register a new account

    Sign in

    Already have an account? Sign in here.

    Sign In Now

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Jefferson Adams
    Celiac.com 11/28/2014 - According to a new study, obesity plays a major part in triggering and prolonging autoimmune diseases, such as celiac disease, Crohn's disease and multiple sclerosis.
    The study appeared recently in Autoimmunity Reviews by Prof. Yehuda Shoenfeld, the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel Aviv University's Sackler Faculty of Medicine and Head of Zabludowicz Center for Autoimmune Diseases at Chaim Sheba Medical Center, Tel Hashomer.
    According to the research, obesity erodes the body's ability to protect itself, triggering a pro-inflammatory environment that promotes the development of autoimmune diseases, hastens their progression, and impairs their treatment.
    For some time now, says Professor Shoenfeld, researchers...


    Jefferson Adams
    Celiac.com 04/06/2015 - Several studies have shown that many patients with celiac disease experience changes in body weight after starting a gluten-free diet, but researchers still don't have much data on rates of metabolic syndrome in this population.
    A team of researchers recently set out to assess rates of metabolic syndrome in patients with celiac at diagnosis, and at one year after starting gluten-free diet. The research team included R. Tortora, P. Capone, G. De Stefano, N. Imperatore, N. Gerbino, S. Donetto, V. Monaco, N. Caporaso, and A. Rispo. They are affiliated with the Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy, or with the Department of Education and Professional Studies, King's College London, London, UK.
    For...


    Jefferson Adams
    Celiac.com 05/18/2016 - Common clinical wisdom, and some data, indicate that patients with celiac disease are likely to be underweight. However, data from west suggest that anywhere from 8% to 40% of celiac patients can be overweight or obese.
    What about normal weight? Can people with celiac disease also have normal body weight? A research team recently set out to determine if people with celiac disease can be normal weight. The research team included I Singh, A Agnihotri, A Sharma, AK Verma, P Das, B Thakur, V Sreenivas, SD Gupta, V Ahuja, and GK Makharia.
    They are variously affiliated with the Department of Gastroenterology and Human Nutrition, the Department of Pathology, the Department of Biostatistics, and the Department of Gastroenterology and Human Nutrition at the All India...


  • Recent Activity

    1. - plumbago replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

    2. - trents replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

    3. - Suzi374 replied to Suzi374's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

    4. - Suzi374 posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Lots of tests

    5. - Peace lily posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Would like to gain weight


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      121,224
    • Most Online (within 30 mins)
      7,748

    Suzi374
    Newest Member
    Suzi374
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Kmd2024
      5
    • Nicola flaherty
      4
    • ItchyHell
      4
    • MMH13
      20
    • Moodiefoodie
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...