No popular authors found.
Ads by Google:

Categories

No categories found.


Get Celiac.com's E-Newsletter





Ads by Google:


Follow / Share


  FOLLOW US:
Twitter Facebook Google Plus Pinterest RSS Podcast Email  Get Email Alerts
SHARE:

Popular Articles

No popular articles found.
Celiac.com Sponsors:

Are People with Celiac Disease At Risk for Dementia?

Celiac.com 11/02/2015 - People with celiac disease frequently report cognitive symptoms when they are exposed to gluten, and clinicians have documented cognitive deficits in some patients with newly diagnosed celiac disease. A team of researchers recently set out to determine whether patients with celiac disease have an increased risk of dementia.

Photo: CC--Salford InstituteThe research team included Benjamin Lebwohl, José A. Luchsinger, Daniel E. Freedberg, Peter H.R. Green, and Jonas F. Ludvigsson. They are variously affiliated with the Celiac Disease Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA; the Department of Medical Epidemiology and Biostatistics, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden; the Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA; the Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA; and the Department of Pediatrics, Örebro University Hospital, Örebro, Sweden.

For their study, the team used a population-based database of adults aged 50 years and older with histologically proven celiac disease; that is, patients showing duodenal/jejunal villous atrophy. The database included patients from all 28 pathology departments in Sweden.

The team compared the incidence of a subsequent dementia diagnosis to those of age- and gender-matched controls.

Ads by Google:

In all, the team reviewed data on 8,846 patients with celiac disease, and 43,474 control subjects, with a median age of 63 years; 56% were female. Over an average follow-up time of 8.4 years, 4.3% of celiac disease patients were diagnosed with dementia, compared with 4.4% of control subjects (HR 1.07; 95% CI 0.95–1.20).

Even though the data showed an increased risk of dementia in the first year following celiac diagnosis (HR 1.73; 95% CI 1.15–2.61), the risk did not continue through entire the follow-up period. Moreover, the increased risk was restricted to celiac patients with vascular dementia (HR 1.28; 95% CI 1.00–1.64), and was not present for Alzheimer’s dementia (HR 1.12; 95% CI 0.91–1.37).

Overall, people with celiac disease do not show any increased risk for dementia, though subgroup analysis suggests that they may have a higher risk for vascular dementia.

Source:

Celiac.com welcomes your comments below (registration is NOT required).












Related Articles



1 Response:

 
Dayle
Rating: ratingfullratingfullratingfullratingfullratingfull Unrated
said this on
09 May 2017 9:39:28 PM PDT
My mother passed away in my arms, she had Parkinson's dementia, her mother the same. Not quite sure I will sleep well tonight, now that I have a great chance of dementia. I refuse to live like that First symptom and I am checking out. I just turned 65 on 5/2.....God bless us all.




Rate this article and leave a comment:
Rating: * Poor Excellent
Your Name *: Email (private) *:




In Celiac.com's Forum Now:


Hi, I?m new to this forum. I?m not a native English speaker so sorry if my English is not perfect :-) For the past 2,5 years (at least) I?ve had typical symptoms of celiac disease.* When I realized this (too late I guess) I went gluten free immediately. So I?ve been gluten-free for approx. ...

I do not have any answers for you but wanted to provide a virtual hug. H. Pylori can cause villi blunting too which i know you said she had. There are also immune deficiency disorders as well. But two copies of the gene... People are offering good advice about the time it can tak...

I just re-read your original post and I am more convinced than ever that it's Candida. The rashes and feeling like something is stuck in her throat are both things I have been very familiar with! Look in her throat with a light and see if you can see any white patches of any kind. Candida has ...

If I thought celiac was what I had, it would be easier for me to get myself into ketosis. Just by saying hey there's a reason you should do this. Gluten intolerance is one thing, knowing what's wrong with me would be another. For people with fears like mine, therapy doesn't work. I have tri...

It can but they have shown time and time again that the liver bounces right back after the medication is stopped. I had some severe abdominal pain, cramping, bloating and major pain that went away after 2-3 days on Fluconazole! I showed visible signs of liver damage in the form of mild jaundice...