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What Can Rainbow Trout Tell Us About Enteritis?

Can trout teach us something about gastroenteritis?


Photo: CC--NFWS

Celiac.com 08/22/2017 - The main source of protein in aquaculture feeds is fishmeal, which is expensive and not conducive to the long-term growth of the industry. Plant protein is much cheaper.

However, replacing fishmeal with a plant-based diet reduces salmonid growth, and soy and other legumes can cause severe enteritis in the fish.

Most rainbow trout are carnivores. Trout do fine on fishmeal, but trout fed a soy-based diet will usually develop gastroenteritis and other problems. One particular strain of trout, however, seems to tolerate soy just fine. Why?

Researchers recently set out to identify genes critical to the rainbow trout strain's tolerance of a soy-based diet. The research team included Jason Abernathy and Ken Overturf from USDA-ARS, USA, and colleagues.

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For their study, the research team compared non-selected and selected rainbow trout raised for 12 weeks on either a fishmeal-based feed or a high-soy, all plant-protein feed.

They then conducted a functional genetic analyses that included differential gene expression, co-expression, and metabolic pathway mapping in muscle and liver tissue. The team found 63 candidate genes that enable trout to tolerate a high-soy diet. The genes may help researchers to uncover and promote plant-diet tolerance in fish.

The researchers also identified risk loci, which are implicated in human inflammatory bowel diseases, suggesting that rainbow trout selected for plant-diet tolerance may provide a biomedical model for better understanding ulcerative colitis and celiac disease.

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Interesting article. I do wonder how she was 'misdiagnosed' though and how she came to the conclusion she wasn't celiac.

Try dropping the oats for while and see if that helps. Some of us, myself included, react to even the ones that are certified as gluten free.

Hey guys, I appreciate the input, you are all very sweet and kind. I do not eat out at all. Only eat food I cook. No alcohol. Only certified gluten-free oats, grains, rice, etc. I have 3 roommates in a little house. I have my own gluten-free section to cook and prepare foo...

What was your gluten free diet like? I wonder if, when you were gluten-free, you went more whole food, less processed food? Or did you continue to eat processed food that was just gluten free? One reason I ask is that I have cut way back on grains and processed foods like gluten-free bread, but o...

Equal parts Hershey Coco Powder and a sweetener with a pinch of salt. Super easy to make your own. I like adding a bit to my coffee with almond milk, and lakanto sugar free maple, or a bit of monk fruit or stevia. PS you might want to drop dairy milk. The enzymes to break it down come from th...