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Collagenous Sprue - The New England Journal of Medicine, December 10, 1970

Collagenous Sprue is a distinctive lesion of the intestinal mucosa associated with progressive malabsorption. The intestinal

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onclick="showHelpTip(event, 'pathology

The branch of medical science that studies the causes and nature and effects of diseases.'); return false">pathology is initially identified with the characteristic flat lesion of untreated Celiac Sprue. Thereafter, bands of eosinophilic hyaline material within the lamina propria become increasingly apparent. As the disease progresses, the mucosa becomes progressively thinner. Therapy, including the gluten-free diet, does not help. Some cases currently designated refractory or unclassified Sprue many prove to be Collagenous Sprue.

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2 Responses:

 
Mona Norton
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
29 Jul 2008 9:05:30 AM PDT
Information is not explained enough. I understand this condition can be fatal if not diagnosed and treated

 
Babboo
Rating: ratingfullratingemptyratingemptyratingemptyratingempty Unrated
said this on
30 Apr 2012 7:48:09 PM PDT
It does a disservice to people newly diagnosed with collagenous sprue to print articles that are so old. As a patient who FORMERLY had c. sprue, I can testify that, with proper care by those practitioners (Dr. Green - my doctor - of Columbia Univ. NYC) who are most familiar with the disease, collagenous sprue can be cured. It is no longer the "death knell" that it used to be.




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Thankyou both of you for your advice, i will have the endoscopy will just have to wait, my blood tests were not hitting the roof with reading but a low to medium result, dont want to be one of them people who have gone gluten free with no need, however i do show typical symptons of celiac but no ...

You are normal! All the things you are going through are normal for someone with celiac disease....probably with any life changing illness. What you need is patience. Most here take a year to heal or longer due to setbacks on the diet or healing from systemic damage. The nervous system seems ...

Yes! Ask for the IgA deficiency test! Why? Well, your doctor did not even follow protocol. In order to validate the IgA celiac tests, he should have determined if you are IgA deficient or not. http://www.mayomedicallaboratories.com/it-mmfiles/Celiac_Disease_Diagnostic_Testing_Algorithm.p...

Almost EVERY single celiac expert in the world and/or groups like the U.K./U.S. Gastroenterologist Associations recommend obtaining biopsies for diagnosing celiac disease. There are some exceptions. If you are too ill to even risk an endoscopy, your celiac panel is extremely high on several of ...

No, I didn't get a endoscopy or even a blood test. I got digestive as well as other problems though on a number of occasions after being gluten free and accidentally eating something with gluten. My symptoms were severe and dramatic so it was obvious to me that I had celaic disease. I wou...