948 Chronic Urticaria (Hives) and Associated Celiac Disease in Children - Celiac.com
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Chronic Urticaria (Hives) and Associated Celiac Disease in Children

Pediatric Allergy and Immunology Volume 16 Issue 5 Page 428 - August 2005

Celiac.com 09/27/2005 – Italian researchers have discovered a link between celiac disease and chronic urticaria (hives). The researchers conducted a case control study that screened 79 children with chronic urticaria for celiac disease, then compared the results to that of 2,545 healthy controls in order to determine the clinical relevance of any association. Children and adolescents who had chronic hives for at least 6 weeks that did not respond to oral antihistamines were used as subjects in the chronic urticaria group, and each group was screened for celiac disease via anti-transglutaminase and anti-edomysial antibodies, with confirmation done via endoscopic intestinal biopsy.

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The researchers found celiac disease in 4 of the 79 chronic urticaria group—a full 5%, and in 17 of the 2,545 controls (0.67%). The four children found to have celiac disease in the chronic urticaria group were put on a gluten-free diet and after 5-10 weeks their chronic urticaria symptoms completely disappeared (while it took 5-9 months for their serological tests for celiac disease to return to normal).

The researchers conclude that the presence of celiac disease in children with chronic urticaria is significantly more frequent than in controls, and children with chronic urticaria should be screened for celiac disease, and, if it is found, they should be treated with a gluten-free diet.

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5 Responses:

 
Terry Coats
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said this on
18 May 2008 10:58:23 AM PDT
Thanks. I have been diagnosed with Celiac since 2001 and am 61 years of age. When I was in high school I developed urticaria that was diagnosed as being associated with heat/exercise. It lasted well into my 20's. Is it likely I had Celiac at that time, or was just predisposed based on my genetics. Thanks. Terry

 
Gail Shallcross
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said this on
17 Jul 2008 7:41:26 PM PDT
My 21 year old son developed hives within the last two months. Antihistamines did not give him much relief. He has strictly monitored his diet for the last 2 days, eliminating gluten. I think that is the ticket.

 
Yum
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said this on
08 Sep 2009 9:39:23 AM PDT
This article is amazing. When I was a child, I spent a lot of time with giant welt-like hives of mysterious origin. We blamed everything from milk to red dye. I bet we have our culprit now.

 
Bennett
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said this on
16 Jan 2011 3:12:14 PM PDT
Been wondering for years why I had such bad digestive problems. Noticed I could tolerate sour dough bread for a while but then my face started breaking out with something like what you describe here. A days ago I stopped all wheat and barley intake and it seems to be getting better. Still need to go in for celiac disease screening via anti-transglutaminase and anti-edomysial antibodies; but it looks like I may have stumbled on something. Thanks!

 
Taneka
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said this on
29 Oct 2012 12:58:33 PM PDT
I was diagnosed with cold urticaria a few years back. It took 11 doctors and 4 years of suffering to figure out that ice cold not touch my skin. Which meant I had to give up my career as an athlete, being unable to ice down any injuries or sore muscles. Although I then knew what was happening, no one could really tell me why. Then the gastrointestinal issues started to occur as well as inflammation in all of my joints. I could barely walk half of the time. I'm on my third week with a gluten-free diet, and I haven't had a stomach ache since. I've also gone down a whole dress size as my swollen belly seems to be melting away. Now I'm thinking gluten was the culprit to my cold allergy too.




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So as many of you might know at only 6 weeks Gluten Free we were shocked to see how many Neurological Issues were resolved for our daughter. It was shocking and amazing. We quickly began to realize that the difficulty swallowing, the Vertigo, the sensory issues were ALL Gluten related. Now in the last 2 weeks it all slipped away and she is almost entirely back to the way she was before we went Gluten Free. We have a pretty good idea why and are taking the steps to remedy it. BUT...it struck me that (for HER sake and the sake of her long term medical records) I need to get the Gluten Ataxia recognized. I realize now how fragile her health is and how hard she will have to fight to STAY healthy. And worse - potentially EVERY cross contamination will take her out for weeks and make her employment opportunities shaky and vulnerable. My Dr. agrees and is sending us to the McMaster Neurological Department (they are cutting edge, up on all that is new etc) to see if they are willing to work with us. She just put the referral in so I have no idea what will come from it. It my result in nothing? Or she may get a Gluten Ataxia diagnosis? I'm not sure but it is worth fighting for.

In my research, diabetes (type 2) is genetic. You either have the genes to develop diabetes or you do not. Additional weight is most likely due to insulin resistance. I happen to be a thin diabetic. I have never been heavy. I was brought up to consume the Standard American diet (SAD) full of process and sugary foods. The problem most celiacs have is that they just simply convert the SAD diet into a gluten free diet. I disagree. We need to consume foods that naturally contain nutrients that are good for us. Fortified foods were only developed during the last century. In the 20's they added iodine to salt to prevent thyroid disease (goiters). In the 30's they added Vitamin D to prevent rickets (fortified milk was better than that nasty cod liver oil). In the 40's they started fortifying flour. Why? They found that kids entering into the military during WWII were malnourished. Yes. They were malnourished. Remember, the Great Depression preceded the war. Read more: https://www.ncbi.nlm.nih.gov/books/NBK208880/ I consume very few grains because I do have diabetes. I eat fresh veggies (full of fiber), meats, fruit, eggs, and dairy along with plenty of fat (which does not raise blood sugar). I do occasionally fall of the wagon, but never the gluten-free wagon! Granted this diet is not for everyone. We must choose what works best for our individual health issues. But chances are we do not need to consume processed junk food in a daily basis. It is not healthy for a celiac. It is not healthy for anyone! So, everything in moderation and enjoy a varied diet.

I felt great a few weeks after going gluten-free. finally started loosing weight as well. the last few weeks I have not felt good. ok in the morning, then slowly start getting brain fog. shakes. pains. is low blood sugar a side affect of going gluten free????

I had a bone scan it didn't show any fractures, basically I left physical therapy in pain, it then went away. But my knee pain and tingling didn't go away so I tried PT again and I left it pain. Then I realized I had celiac and now all my pain is gone other then the back pain.. I'm basically worried I healed from the celiac and PT caused a whole new problem that never had to happen.

I am trying to find out if going gluten-free can cause low blood sugar. I felt so much better when going gluten-free, but now I feel weak, shaky, tired