Hookwormed status report
Not much going on to report. My last inoculation of 25 Necator americanus hookworm larvae occurred April 11 2025, and I'm due to start incubating Aug 27 2026 and inoculate again with 25 larvae Sep 3 2025. Over the years I've seen my celiac/ulcerative colitis symptoms return six month-ish after inoculation, so I've settled on a frequency of a little less than 5 months, or in this instance, 4.79 months.
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Human hookworms (NA) don't reproduce in the body and since my immune system is constantly attacking them, I assume that attrition starts in earnest probably at the halfway point and by 5 months I might have between 10-18 left. This is strictly a guess but I think a reasonable one. I haven't noticed any GI symptoms at the 5 month mark, so that implies 10-18 functioning hookworm adults is all I need to stay healthy, but to stay that way for the duration I need to inoculate with 25 larvae. I'm obviously just spitballing here, but I'll continue to think this way until evidence to the contrary comes in. Everyone is different in terms of how many larvae they need to feel better and for how long. It all depends on the host's immune system and perhaps whether the person suffers from Inflammatory Bowel Disease. IBD sufferers tend to burn through hookworms faster than the general population.
Spidey guarding my microscope until the next incubation cycle.
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