Celiac.com 06/04/2020 - Currently, in order to properly diagnose celiac disease based on serology and duodenal histology, doctors need patients to be on gluten-containing diets, even if they are causing symptoms, and this is called a "gluten challenge." This is a problem for many people, especially those who have already given up gluten, and see benefits from the gluten-free diet. For those people, going back on gluten for several weeks can be demoralizing. For many, it's a deal breaker. This can present challenges for doctors attempting to diagnose celiac disease.
According to the University of Chicago Celiac Disease Center, a gluten challenge should be done as follows:
Eat gluten prior to celiac disease blood tests: The amount and length of time can vary, but is somewhere ...

Celiac.com 09/24/2020 - Celiac disease is an autoimmune condition in which eating wheat, rye, or barley triggers an adverse immune reaction in the gut. Celiac disease affects about one percent of the population. Diagnosis can be a long and arduous process. In the United States, the average person with celiac disease can wait up to ten years from the time of first symptoms to diagnosis. Left undiagnosed, autoimmune disease can cause organ damage and bowel cancer.
Anyone who has ever had to suffer through a long, convoluted process to get their celiac disease diagnosis can now rejoice for any new celiacs going forward. That's because researchers have developed a single blood test that can diagnose celiac disease without biopsy. Until now, the "gold standard" for celiac diagnosis was...

Celiac.com 06/08/2023 - For people who suspect they have celiac disease, an accurate diagnosis is crucial for managing health and making informed dietary choices. Traditionally, the gold standard for celiac diagnosis has involved a gluten challenge, where individuals are required to consume gluten-containing foods to induce disease activity. 
However, this approach can be burdensome and time-consuming. Now, a new study conducted at two US centers has shed light on new biomarkers that could help to rapidly improve the way celiac disease is diagnosed and researched.
The Research Team
The research team included Maureen M. Leonard, Jocelyn A. Silvester, Daniel Leffler, Alessio Fasano, Ciarán P. Kelly, Suzanne K. Lewis, Jeffrey D. Goldsmith, Elliot Greenblatt, William W...

Celiac.com 10/23/2023 - A recent study conducted by a team of US investigators is shedding light on the use of European thresholds for diagnosing celiac disease in North America. This study seeks to determine how often biopsies are performed on children who are considered at high risk for celiac disease based on common diagnostic tests, yet meet the criteria for non-biopsy diagnoses according to European standards.
Dr. Denis Chang, the study's lead author, discussed the trial's design and its implications for celiac disease diagnostics in North America during an interview with HCPLive at the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) 2023 Annual Meeting in San Diego.
Celiac disease is an autoimmune disorder that affects the...