Question About Hla Testing.

[smjohn]

Hello,

I was tested in June for tTg antibodies and was positive. According to the labs, anything higher then 8 was positive, I was 19. I had a upper endo biopsy and it was negative.

I had a rough summer. I was diagnosed with SLE(Lupus). I had a positive ANA, high sed rate (106), positive double stranded DNA, low complement levels. Saw a rheumatologist and was put on steroids and immunosuppressants. I am s-l-o-w-l-y getting better.

I am not convinced I don't have celiac as well. I have so many of the symptoms of celiac disease. The bloating, abdominal pain, diarhea alternating with somewhat normal stool, foul smelling stool, headaches, dental enamel defects all are present. I also have what doctors call a "dermatitis" all over my arms, legs and butt. It itches like crazy.

I have seen some articles on people who were diagnosed as having SLE when it was really celiac. I am just wondering if I have both?

I had some HLA testing done by a neurologist. They found me to be HLA B27 positive as well as DRB1(DR4) positive. Isn't DR4 a celiac marker?

Any input would be appreciated.

[kelliac]

  smjohn said:

Hello,

I was tested in June for tTg antibodies and was positive. According to the labs, anything higher then 8 was positive, I was 19. I had a upper endo biopsy and it was negative.

I had a rough summer. I was diagnosed with SLE(Lupus). I had a positive ANA, high sed rate (106), positive double stranded DNA, low complement levels. Saw a rheumatologist and was put on steroids and immunosuppressants. I am s-l-o-w-l-y getting better.

I am not convinced I don't have celiac as well. I have so many of the symptoms of celiac disease. The bloating, abdominal pain, diarhea alternating with somewhat normal stool, foul smelling stool, headaches, dental enamel defects all are present. I also have what doctors call a "dermatitis" all over my arms, legs and butt. It itches like crazy.

I have seen some articles on people who were diagnosed as having SLE when it was really celiac. I am just wondering if I have both?

I had some HLA testing done by a neurologist. They found me to be HLA B27 positive as well as DRB1(DR4) positive. Isn't DR4 a celiac marker?

Any input would be appreciated.

Did a little research. It looks to be celiac, but don't quote me. Check out these links regarding DR4 and decide for yourself. As for the rash, has anyone mentioned Dermatitis Herpetiformis? Open Original Shared Link

Open Original Shared Link

Open Original Shared Link

[smjohn]

I've only been told it "looks" like dermatitis. I am wondering if it needs to be biopsied?

What tests should I have done other than tTG? I am on an immunosuppresant and 10 mg of prednisone daily. Will that affect my results?