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How to interpret blood tests


Raspberry

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Raspberry Newbie

About 4 years ago, at my insistence, my doctor tested my for celiac.  The tests came out negative, but now I am looking at them again and questioning the analysis.

IgA = 214

tTg IgA = 8     The test results say that anything is 19 is negative, but that seems like a high bar to me. 

tTG IgA = 3

For years, I have neuropathy in my feet which is getting progressively worse.  The pain is just moderate now, but I am concerned about it getting even worse in the future.  I am not diabetic, and doctors have no clue what could be causing it.  

Would anyone have an opinion whether IgA is considered positive?  


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squirmingitch Veteran

We can't tell without the reference ranges on those bloods. Different labs have different ranges so it's important to have those ranges.

Celiac can present at any time in life so if you had tests 4 years ago that does not mean you're not celiac forever. It might be smart to get tested again BUT make sure you're eating gluten (at least a slice of bread or 2 saltines every day) for 12 weeks otherwise you'll get false negatives.

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    • thejayland10
      thank you, i have been doing that the last few weeks and will continue to do so. I had not had my ttg iga checked since I was diagnosed 14 yrs ago so I am not sure if they ever dropped below the 15-20 range.    all my other labs are completely normal but I am concerned that this may be signs of refractor celiac or something else since I'm so careful with gluten-free diet 
    • Scott Adams
      Around 9% of celiacs cannot tolerate any oats, even gluten-free oats. It might be worth eliminating them for a few months, then get re-tested.
    • thejayland10
      I only eat certifed gluten-free products but a lot of which are processed. Could there be trace gluten in those or is that very unlikely? 
    • Scott Adams
      For people with celiac disease hidden gluten in their diets is the main cause of elevated Tissue Transglutaminase IgA Antibodies (tTG-IgA), but there are other conditions, including cow's milk/casein intolerance, that can also cause this, and here is an article about the other possible causes (you may want to avoid oats):    
    • thejayland10
      Hello,  I have seen numerous doctors and they can't seem to pin point why my ttg iga is still mildly elevated at 16-20 even after being gluten free for over 10 years. I follow a very strict diet and don't eat out. All my other blood tests such as ema, DGP IGA / IGG, vitamin levels, CBC, and dexa scan were normal. 
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