Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

B-complex vs B-12


Moccajoe

Recommended Posts

Moccajoe Apprentice

I heard that we shouldn’t take B complex vitamins. But plain B12. Why is that?


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



ravenwoodglass Mentor
11 hours ago, Moccajoe said:

I heard that we shouldn’t take B complex vitamins. But plain B12. Why is that?

You can and should take a B Complex but you should add a sublingual B12. Those dissolve under the tongue and are absorbed there bypassing the damaged gut. Don't be disturbed by the levels in the tablet as your body will excrete what it doesn't need.

knitty kitty Grand Master
(edited)

Cobalamine (B12) requires folate (B9) and pyridoxine (B6) to work properly.   Pyridoxine works with thiamine (B1).  Thiamine works with niacin (B3).  Thiamine and pyridoxine like to work with riboflavin (B2).  They are all interdependent for proper functioning.  

By only supplementing B12, a deficiency in folate or pyridoxine could occur.  Similarly other vitamins that work with enzymes made with these vitamins would become nonfunctional.

The B vitamins are water soluble.  B12 is the only one that can be stored for any great length of time.  It can be stored in the liver for three to five years.  Once your liver stores of B12 are replenished, the excess is excreted in urine.  Riboflavin can't be stored very long at all.  You need to consume some B2 every day.  Thiamine can only be stored for 28 days, but the body uses various amounts every day.  If not replenished, you can become deficient in thiamine in as little as nine days.

Taking just B12 won't prevent deficiencies in other B vitamins.  B12 can't do the jobs that the other B vitamins do.  

Edited by knitty kitty
Add more information
Sabaarya Community Regular
7 hours ago, knitty kitty said:

Cobalamine (B12) requires folate (B9) and pyridoxine (B6) to work properly.   Pyridoxine works with thiamine (B1).  Thiamine works with niacin (B3).  Thiamine and pyridoxine like to work with riboflavin (B2).  They are all interdependent for proper functioning.  

By only supplementing B12, a deficiency in folate or pyridoxine could occur.  Similarly other vitamins that work with enzymes made with these vitamins would become nonfunctional.

The B vitamins are water soluble.  B12 is the only one that can be stored for any great length of time.  It can be stored in the liver for three to five years.  Once your liver stores of B12 are replenished, the excess is excreted in urine.  Riboflavin can't be stored very long at all.  You need to consume some B2 every day.  Thiamine can only be stored for 28 days, but the body uses various amounts every day.  If not replenished, you can become deficient in thiamine in as little as nine days.

Taking just B12 won't prevent deficiencies in other B vitamins.  B12 can't do the jobs that the other B vitamins do.  

Hi. I was diagnosed with celiac 2 months ago and I do follow gluten-free diet,but still buy gluten-free breads,snacks,chocolates,not sure if I should. I’m taking B-complex and D for almost 20 days now,but I feel like it made my stomach upset. I stopped iron because not sure if they are gluten free. I’m sure as a celiac for how long I should take all the vitamins and Iron?? Is it like for months or just short period of time..

Thank you,

Saba

knitty kitty Grand Master
(edited)

@Sabaarya,

Are you taking your B Complex with meals?  Try taking it halfway through your meal and see if that helps you avoid the stomach upset.

I suggest taking supplements for three months.  

Edited by knitty kitty
Add more information
AlwaysLearning Collaborator

I think the first question is, have you tested as being deficient in B12?

If yes, the next question is, have you been gluten free for long enough that you would expect to no longer have malabsorption issues to cause vitamin deficiencies?

If yes to both, the next questions are, have you been tested for thyroid problems, are you vegan/vegetarian, do you lack intrinsic factor? 

I'm a big believer in only supplementing deficiencies you actually have. There can be a lot of issues with the way supplements are made and they can cause a whole slew of side effects, not to mention, not be completely bio-identical. But if you "should" be healed after being gluten free for a while and are still having difficulties with deficiencies, it might be time to investigate if there are other causes.

Better to treat the cause than to endlessly supplement a symptom.

 

Best of luck to you and good for you for seeking out more information. 

 

 

knitty kitty Grand Master

Please, please, everyone, read this article!!!

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/

 

Many studies have been done on the supplementation of singular vitamins, frequently B12, or combinations of vitamins like B12 with folate(B9) and maybe including pyridoxine(B6).  

Few studies have been done on the full spectrum of all eight B vitamins together.  Recent studies are showing the benefits of supplementing all eight B vitamins (as in multivitamins).  Recent studies also show the benefits of supplementing B vitamins at higher levels than set in the Recommended Daily Allowance (RDA).

Blood tests for vitamins are often inaccurate.  The vitamins are used inside cells of tissues and the amount not there has no or little correlation to the level floating around in the blood.  By the time a deficiency is picked up by a blood test, the deficiency is further progressed and has caused more damage.

This article shows an example....

"Undetected vitamin B12 deficiency due to false normal assay results"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827408/

Yes, there are circumstances where bioavailability or not being bio-identical can be a problem.    But we have a choice as to which vitamin supplements we choose.  High quality bioavailable supplements are out there.  


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Sabaarya Community Regular
On 10/19/2021 at 5:55 PM, knitty kitty said:

@Sabaarya,

Are you taking your B Complex with meals?  Try taking it halfway through your meal and see if that helps you avoid the stomach upset.

I suggest taking supplements for three months.  

I’m not taking them with meals,I do after my meals. I will try to take with meal and see if it’s better. In your other posts you mentioned that you removed your galbbladder. Does celiac affect gallbladder function? Can I ask what kind of symptoms did you have and how did you find out that you have celiac?

thank you 

knitty kitty Grand Master
11 minutes ago, Sabaarya said:

I’m not taking them with meals,I do after my meals. I will try to take with meal and see if it’s better. In your other posts you mentioned that you removed your galbbladder. Does celiac affect gallbladder function? Can I ask what kind of symptoms did you have and how did you find out that you have celiac?

thank you 

Celiac doesn't directly affect the gallbladder, but thiamine (Vitamin B1) can affect the gallbladder.  The gallbladder needs thiamine to make bile and secrete it at meal times.  Celiac Disease causes malabsorption which results in malnutrition and vitamin and mineral deficiencies.

My symptoms were digestive problems, gallbladder problems, diarrhea, and lots of vitamin deficiencies that went undiagnosed.  My doctors were not very educated about Celiac Disease.  

I started this thread with my research references and my experiences here...

Keep us posted on your progress!  I hope taking your vitamins with meals helps!

 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,663
    • Most Online (within 30 mins)
      7,748

    Funnybone
    Newest Member
    Funnybone
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Inkie
      Thank you for the information ill will definitely bring it into practice .
    • Scott Adams
      While plain, pure tea leaves (black, green, or white) are naturally gluten-free, the issue often lies not with the tea itself but with other ingredients or processing. Many flavored teas use barley malt or other gluten-containing grains as a flavoring agent, which would be clearly listed on the ingredient label. Cross-contamination is another possibility, either in the facility where the tea is processed or, surprisingly, from the tea bag material itself—some tea bags are sealed with a wheat-based glue. Furthermore, it's important to consider that your reaction could be to other substances in tea, such as high levels of tannins, which can be hard on the stomach, or to natural histamines or other compounds that can cause a non-celiac immune response. The best way to investigate is to carefully read labels for hidden ingredients, try switching to a certified gluten-free tea brand that uses whole leaf or pyramid-style bags, and see if the reaction persists.
    • Scott Adams
      This is a challenging and confusing situation. The combination of a positive EMA—which is a highly specific marker rarely yielding false positives—alongside strongly elevated TTG on two separate occasions, years apart, is profoundly suggestive of celiac disease, even in the absence of biopsy damage. This pattern strongly aligns with what is known as "potential celiac disease," where the immune system is clearly activated, but intestinal damage has not yet become visible under the microscope. Your concern about the long-term risk of continued gluten consumption is valid, especially given your family's experience with the consequences of delayed diagnosis. Since your daughter is now at an age where her buy-in is essential for a gluten-free lifestyle, obtaining a definitive answer is crucial for her long-term adherence and health. Given that she is asymptomatic yet serologically positive, a third biopsy now, after a proper 12-week challenge, offers the best chance to capture any microscopic damage that may have developed, providing the concrete evidence needed to justify the dietary change. This isn't about wanting her to have celiac; it's about wanting to prevent the insidious damage that can occur while waiting for symptoms to appear, and ultimately giving her the unambiguous "why" she needs to accept and commit to the necessary treatment. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. One test that always needs to be done is the IgA Levels/Deficiency Test (often called "Total IGA") because some people are naturally IGA deficient, and if this is the case, then certain blood tests for celiac disease might be false-negative, and other types of tests need to be done to make an accurate diagnosis. The article includes the "Mayo Clinic Protocol," which is the best overall protocol for results to be ~98% accurate.    
    • Scott Adams
      Welcome to the community! Generally, for a gluten challenge before celiac disease blood tests, Tylenol (acetaminophen) is considered safe and should not interfere with your antibody results. The medications you typically need to avoid are those like ibuprofen (Advil, Motrin) or naproxen (Aleve) that can cause intestinal irritation, which could potentially complicate the interpretation of an endoscopy if you were to have one. However, it is absolutely crucial that you confirm this with either your gastroenterologist or your surgeon before your procedure. They know the specifics of your case and can give you the definitive green light, ensuring your surgery is comfortable and your celiac testing remains accurate. Best of luck with your surgery tomorrow
    • Xravith
      Thank you for the advice. I’ve actually never checked for nutritional deficiencies, but for as long as I can remember, I’ve always taken vitamin and mineral supplements — otherwise my symptoms get worse. This week I stopped eating gluten to confirm whether my symptoms are really caused by it. Starting next week, I’ll reintroduce gluten — it’s sad to go back to how I was before — but at least I’ll be able to take the necessary tests properly. I think the diagnostic process will be long, but at least I’m happy that I finally decided to address this doubt I’ve had for years.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.