Help me with my test results please

[kab3706]

Hi there,

Below are my celiac panel test results. I'm still waiting to hear back from my doctor. Can anyone give me an insight as to what this means? Thanks so much!

Celiac Total IgA     Result: 369 mg/dL     Standard Range:  60 - 350 mg/dL         HIGH

Transglutaminase IgA Antibodies       Result: 0.9 U/mL     Standard Range: <7.0 U/mL U/mL

[trents]

Welcome to the forum, kab3706!

Your total IgA is not deficient. If total IgA is lower than normal it will skew individual IgA fractions downward, such as the Transglutaminase IgA Antibodies. So, this is not your problem and therefore your tTG-IGA at 0.9 U/mL is an accurate reading. Just from that limited amount of data , there is no indication you have celiac disease. But there are other celiac antibody tests that could have been run. Too bad they were not. The tTG-IGA is the most popular with physicians and relatively inexpensive. Other celiac antibody tests could catch what the tTG-IGA may miss since it is not a perfect test.

Your results do not rule out NCGS (Non Celiac Gluten Sensitivity), however. celiac disease and NCGS share many of the same symptoms. There is no test for NCGS so celiac disease must first be ruled out. NCGS is 10x more common than celiac disease and some experts feel it can be a precursor to celiac disease. The antidote is the same for both - total abstinence from gluten for life.

 

[knitty kitty]

@kab3706,

Some younger people can have negative ttg-IgA, but be positive on DGP-IgA test.  

Were you eating gluten consistently in the two to three months before your blood tests?   The tTg-IgA tests for antibodies to gluten.  If you were gluten free, you would not have been making antibodies, and the test would give a false negative.

Do you have diabetes or anemia?  These can cause false negatives on tTg-IgA.

Have you considered genetic testing?  Celiac genes are hereditary.

Edited February 10, 2023 by knitty kitty
Typo correction