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Algaecal causing high result in Coronary Artery Calcium test?


Capt Jules
Go to solution Solved by Scott Adams,

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Capt Jules Newbie

I was instructed to take Algaecal as alternative to bisphosphonate drugs for osteoporosis. I did for 2 years, 1200 mg a day. My cholesterol spiked above normal during this time. We watched it and finally determined best to get a test to see if calcium was causing the spike. I have never had high cholesterol before. Could the celiac non absorption have caused calcium to build in my arteries? Now put on a statin to lower cholesterol (began at 180 went to 240 while on Alcagal). thanks


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  • Solution
Scott Adams Grand Master

There is no direct evidence that AlgaeCal causes elevated coronary artery calcium (CAC) scores or significantly raises cholesterol levels. However, excessive calcium supplementation—especially without adequate vitamin K2 (which helps direct calcium to bones rather than arteries)—could theoretically contribute to vascular calcification over time, particularly in individuals with absorption issues like celiac disease. Since celiac disease can impair nutrient absorption, it’s possible that imbalances in calcium metabolism or deficiencies in cofactors like vitamin D and K2 might play a role. The spike in your cholesterol is unusual and may not be directly linked to AlgaeCal, but it’s worth discussing with your doctor whether other dietary or metabolic factors (like thyroid function or inflammation) could be influencing both your cholesterol and CAC results. Statins may help manage cholesterol, but further testing (e.g., vitamin K2 status, inflammation markers) could provide more insight into the underlying cause. Always consult your healthcare provider before adjusting supplements or medications.

knitty kitty Grand Master

I've found some articles that might be of interest to you.  The malabsorption of Celiac Disease does lower your vitamin levels, essential nutrients our bodies cannot make.  Vitamin B1 is especially important to our heart health.

 

Current Evidence and Future Perspectives of the Best Supplements for Cardioprotection: Have We Reached the Final Chapter for Vitamins?

https://pmc.ncbi.nlm.nih.gov/articles/PMC11269067/

 

The Pivotal Role of Thiamine Supplementation in Counteracting Cardiometabolic Dysfunctions Associated with Thiamine Deficiency

https://pmc.ncbi.nlm.nih.gov/articles/PMC11988323/

 

The relationship between dietary vitamin B1 intake and severe abdominal aortic calcification among the general population in the United States

https://pmc.ncbi.nlm.nih.gov/articles/PMC11599191/

Vicious cycle of vitamin B1 insufficiency and heart failure in cardiology outpatients

https://pmc.ncbi.nlm.nih.gov/articles/PMC11579856/

Hope this helps!

Scott Adams Grand Master

Thanks for sharing!

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    • par18
      Thanks for the reply. 
    • Scott Adams
      What you’re describing is actually very common, and unfortunately the timing of the biopsy likely explains the confusion. Yes, it is absolutely possible for the small intestine to heal enough in three months on a strict gluten-free diet to produce a normal or near-normal biopsy, especially when damage was mild to begin with. In contrast, celiac antibodies can stay elevated for many months or even years after gluten removal, so persistently high antibody levels alongside the celiac genes and clear nutrient deficiencies strongly point to celiac disease, even if you don’t feel symptoms. Many people with celiac are asymptomatic but still develop iron and vitamin deficiencies and silent intestinal damage. The lack of immediate symptoms makes it harder emotionally, but it doesn’t mean gluten isn’t harming you. Most specialists would consider this a case of celiac disease with a false-negative biopsy due to early healing rather than “something else,” and staying consistently gluten-free is what protects you long-term—even when your body doesn’t protest right away.
    • Scott Adams
      Yes, I meant if you had celiac disease but went gluten-free before screening, your results would end up false-negative. As @trents mentioned, this can also happen when a total IGA test isn't done.
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