Antibodies For Testing--days

[Dyang]

It seems that it would only take a few days of eating wheat for antibodies to be formed and detected. What I am driving at is that after trial with gluten-free diet one can be tested for celiac after only a few days of eating wheat. Am I right?

What is the great necessity to confirm celiac disease before trying gluten-free diet?

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“Dr Anderson's team then took 12 patients with coeliac disease whose condition was stable on a gluten free diet and asked them to eat four slices of bread every day for three days. Blood tests taken before and after the bread challenge showed that only two of the 51 gliadin peptides had stimulated an immune response. These two peptides overlapped each other, and seemed to require treatment with transglutaminase to be active. The specific lymphocytes that had been induced by these peptides appeared in the blood 6-8 days after the gluten challenge.”

[tarnalberry]

It takes longer than a few days because, if you've been gluten free for very long, your intestines are relatively healed, and the antibodies that your intestines are producing for those four days are not getting into the blood stream. Ordinarily, it is very small molecules that are released into the bloodstream from the intestines, not large ones like antibodies. That's why three months is recommended - time to damage the intestines enough for the antibodies to be freely flowing into the bloodstream.