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Lichen Plainus


loraleena

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loraleena Contributor

My ex-husband has had a rash all over for a year and a half. They have told him it it Lichen Planus. It is now in his mouth. I wondered at first if it was DH. Doc doesn't think so. He stopped wheat for a while but not gluten ( I can't convince him). It did nothing. I was wondering if anyone had this and if it is connected to celiac. I told him he should be tested, but I don't think he wants to go there. Given that I have suffered for years I hate to see him or anyone else suffer needlessly!


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2kids4me Contributor

The only connection is that it is an immune mediated disease and it is not uncommon to develop other autoimmune conditions. With any skin disorder (autoimmune or not), diet can play a role is the severity of the outbreak, and supplements with Omega fatty acids and avoiding refined prodcuts can help some people.

The exact cause of LP is not known. The pathogenesis of LP is immunologically mediated. Whether the foreign antigen is a virus or a drug is not known. Langerhans cells process antigens, which are then presented to T lymphocytes. This stimulated lymphocytic infiltrate is epidermotropic and attacks keratinocytes. During this lymphocytotoxic process, the keratinocytes release cytokines that attract more lymphocytes. This process has been referred to as the lichenoid tissue reaction.

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