Can Anyone Clearly Explain Iga And Igg Differences?

[MauriceGreene]

I am interested to know. Say for example your blood work is:

ttg: 18

IgA: 15

IgG: 66

as aposed to

ttg: 18

IgA: 66

IgG: 15

[Jestgar]

IgA is a quick, not very specific response.

IgG is a slower, more directed response.

Initial response would be IgA, followed by IgG as your cells learn to recognize the offending protein.

[ajay]

There are different subsets of antibodies, and each tends to have its own specialty.

Generally, IgA is a "front line" response and found is found in secretions (the gunk in your eyes, ears, etc.)

IgA tries to keep infections out of your body in the first place.

IgM is the first phase of internal antibodies produced once a problem is found internally. IgM titer spikes early in infection.

IgG is the serious, specific response. In an infection, your IgG titer looks like a bell curve over time. It starts out low, builds up, and lowers as you clear the infection.

That's a really rough explanation; I'm just trying to give you the general idea.

I would guess that, as Jestgar said, the two profiles represent different stages of the disease.

Side note: IgE antibodies are usually blamed for environmental allergens (dust/dander/pollen/etc.)...