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Weak Positive Ttg Iga Test


dmurth01

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dmurth01 Newbie

Hi All,

I'm new (obviously) and so glad to find this board.

I went to a GP last week for a check up, but also told her about my fairly recent symptoms (since this summer):

  • Gas
  • Constant abdominal bloating
  • Extremely distended, hard stomach (used to be flat!)
  • Major fatigue, even after a full night of sleep
  • Frequent constipation
  • Depression & anxiety with moodswings
  • Cloudy, "foggy" feeling, especially after eating
  • Ravenous hunger, especially worsened by sweets and carbs

*I haven't had a period in 1.5 years also.

She ran blood tests including a celiac panel, and my tTg iGA test came back as weak positive. The number was 21.

This is the reference used:

0-19 = Negative

20-29 = Weak positive

30+ = Moderate to strong positive

Other blood tests all came back in the normal range.

She's referred me to a GI specialist, but my appointment isn't for a month! I want to go gluten-free so badly right now but I know from reading things here that it might cause negative results at my next appt. so I'm staying on gluten for now.

Any advice for the next month? It's killing me to keep eating gluten while I know it's probably hurting me.

Thanks!


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Wolicki Enthusiast

If you want the endo, then you must stay on gluten- they say the equivalent of 3 slices of wheat bread daily, for an accurate result. If you don't need the official diagnosis, then say the heck with the endo and start the diet. As far as I am concerned, a positive diet response is pretty "official." Good luck with whichever you choose.

homemaker Enthusiast
Hi All,

I'm new (obviously) and so glad to find this board.

I went to a GP last week for a check up, but also told her about my fairly recent symptoms (since this summer):

  • Gas
  • Constant abdominal bloating
  • Extremely distended, hard stomach (used to be flat!)
  • Major fatigue, even after a full night of sleep
  • Frequent constipation
  • Depression & anxiety with moodswings
  • Cloudy, "foggy" feeling, especially after eating
  • Ravenous hunger, especially worsened by sweets and carbs

*I haven't had a period in 1.5 years also.

She ran blood tests including a celiac panel, and my tTg iGA test came back as weak positive. The number was 21.

This is the reference used:

0-19 = Negative

20-29 = Weak positive

30+ = Moderate to strong positive

Other blood tests all came back in the normal range.

She's referred me to a GI specialist, but my appointment isn't for a month! I want to go gluten-free so badly right now but I know from reading things here that it might cause negative results at my next appt. so I'm staying on gluten for now.

Any advice for the next month? It's killing me to keep eating gluten while I know it's probably hurting me.

Thanks!

That seems like a positive test to me! Just like a pregnancy test, no one is just a little pregnant! LOL

One thing to remember is that if you go gluten-free prior to your endoscope it might skew your results....

You do have to eating gluten for the endoscopy to be accurate...

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      Welcome to the forum, @Mmoc! Please include the reference ranges for the IGA and the TTG tests in your next post if you have access to them. We cannot comment much otherwise as different labs use different reference ranges for these tests and also different units of measurement. There are no universal standards as of yet so the raw test numbers are not always helpful. Having said that, if your IGA (what we usually call "total IGA") is low, the TTG-IGA score will be skewed and cannot be trusted. Other kinds of tests for celiac disease would need to be run, particularly those in the IGG family of tests. Perhaps this will be helpful:  
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