We're 4 For 4...

[luvs2eat]

Oldest daughter has just been diagnosed. So, I've been gluten-free for 9 years, middle daughter for about 4, youngest daughter for 1 and now oldest's positive bloodwork makes it 4 for 4. At least she lives in Portland where shopping for gluten-free food and eating out is a heckuva lot easier than it is in rural Arkansas! And at least she's been familiar w/ the whole process for a really long time!

[Takala]

This is going to make your family reunions, holidays, and get togethers .... uhm, so much easier !

[ravenwoodglass]

We had a four in four also. Celiac is so much more common than doctors have previously thought. It isn't inherited the way most 'diseases' are. Most diseases have a 1 in 4 chance of inheritance. I do so wish I still had the link that explained why. If memory serves it is because it is a haplogroup (sp) rather than a defect. So it doesn't follow the same inheritance pattern as something like, for example, cystic fibrosis.

[Philippa]

We had a four in four also. Celiac is so much more common than doctors have previously thought. It isn't inherited the way most 'diseases' are. Most diseases have a 1 in 4 chance of inheritance. I do so wish I still had the link that explained why. If memory serves it is because it is a haplogroup (sp) rather than a defect. So it doesn't follow the same inheritance pattern as something like, for example, cystic fibrosis.

I don't think researchers know all the genes involved in celiac disease yet. Like most autoimmune diseases there are multiple genes involved, which is why it isn't inherited in a simple, predictable way, like cystic fibrosis (which is a single gene defect). With celiac and other autoimmune diseases there are environmental factors as well.

[luvs2eat]

My doc told me it was common in those of Irish ancestry (me, altho there's no fam history). I've read that it's also common in Jews (their dad, altho there's no fam history there either). The kids were doomed!! Oldest DD is just happy she got to eat gluten the longest.