Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Gluten Withdrawal And The Thyroid


Marz

Recommended Posts

Marz Enthusiast

So as a quick update to my progress, I started the gluten free diet on Saturday, felt fantastic on the weekend, and then hit a wall on Monday.

My "gluten withdrawal" symptoms (some of which overlap with my gluten-poisoning symptoms marked with *, but I'm fairly sure I've been strictly gluten-free) :

- Nausea*

- Depression, irritability, crying over nothing, anxiety*

- Stomach upset* (to be expected, but stomach is otherwise a *lot* better).

- Sore throat/feeling like I have something caught in my throat/swelling.

The sore throat was interesting - the pain/swelling feels like it's coming from my thyroid gland, I swear! I've never had pain in that area, it's right by the adam's apple, and apparently that's where the gland is. I can even feel it, feels like it's a bit swollen. No other symptoms of a cold, I'm not feeling "sick", so I don't think it's an infection.

Was reading up on hypo/hyper thyroidism, and thought it was interesting how many symptoms of hyperthyroidism correspond to gluten-withdrawal symptoms. From reading through this forum, I've seen a number of similar complaints after going gluten-free, except maybe weight loss, hair loss.

Open Original Shared Link

Major clinical signs include weight loss (often accompanied by an increased appetite), anxiety, intolerance to heat, hair loss, muscle aches, weakness, fatigue, hyperactivity, irritability, apathy, depression, polyuria, polydipsia, delirium, tremor, pretibial myxedema, and sweating. Additionally, patients may present with a variety of symptoms such as palpitations and arrhythmias (notably atrial fibrillation), shortness of breath (dyspnea), loss of libido, nausea, vomiting, and diarrhea.[citation needed] Long term untreated hyperthyroidism can lead to osteoporosis. These classical symptoms may not be present often in the elderly.

So this is my theory - initially when going off gluten, your thyroid gland which was previously being under-regulated/suppressed by gluten-poisoning, now suddenly is released from this suppression. All the up-regulating mechanisms in your body goes into overdrive (There's a number of hormones involved in this, too long to explain!), results in temporary *hyperthyroidism*.

Hyperthyroidism is also associated with an enlarged thyroid. Not sure if pain comes into it.

Good withdrawal symptoms:

- Had the best sleep of my life on Saturday evening. Awoke on Sunday completely awake and refreshed. It's crazy that I've felt so groggy in the morning for so long, I forgot what it's like to feel normal!

- My intermittent nose bleeds have suddenly stopped, which is weird.

- Other than the mild nausea and moderate stomach pain my GIT system seems a lot more stable.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



maile Newbie

So this is my theory - initially when going off gluten, your thyroid gland which was previously being under-regulated/suppressed by gluten-poisoning, now suddenly is released from this suppression. All the up-regulating mechanisms in your body goes into overdrive (There's a number of hormones involved in this, too long to explain!), results in temporary *hyperthyroidism*.

Hyperthyroidism is also associated with an enlarged thyroid. Not sure if pain comes into it.

Hypo/Hyperthyroidism is definitely associated with gluten intolerance however, it's really hard to go hyper on a temporary basis. Hyper is usually recognised by rapid heart rate/pulse, increased temperatures, shakiness and many loose stools in a day (which as you pointed out are also classic gluten poisoning symptoms)

what you may have experienced is a "thyroid dump" where the body dumps a whole bunch of stored thyroid into the system in a short while, what you want to look for after that is whether your thyroid begins underperforming (constipation, inappropriate weight gain, FATIGUE, hair loss etc) which is what usually happens when one has an inflamed thyroid gland.

Marz Enthusiast

Thanks for the info, my theory was wrong :) Swelling is down so it must've been a temporary thing, and still not sure if it was even thyroid related.

beansmom Newbie

Thanks for the info, my theory was wrong :) Swelling is down so it must've been a temporary thing, and still not sure if it was even thyroid related.

Hi. Found your theory interesting. Actually, I have thought something quite opposite. I just started a gluten challenge and a week into it have noticed that my thyroid hurts to touch. I have autoimmune thyroiditis and have been on thyroid replacement for some time. I was thinking that the antibodies to the gluten may cross react with the thyroid antibodies...

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      131,899
    • Most Online (within 30 mins)
      7,748

    dcarter1682
    Newest Member
    dcarter1682
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.4k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      Welcome to the forum, @Judy M! Yes, he definitely needs to continue eating gluten until the day of the endoscopy. Not sure why the GI doc advised otherwise but it was a bum steer.  Celiac disease has a genetic component but also an "epigenetic" component. Let me explain. There are two main genes that have been identified as providing the "potential" to develop "active" celiac disease. We know them as HLA-DQ 2.5 (aka, HLA-DQ 2) and HLA-DQ8. Without one or both of these genes it is highly unlikely that a person will develop celiac disease at some point in their life. About 40% of the general population carry one or both of these two genes but only about 1% of the population develops active celiac disease. Thus, possessing the genetic potential for celiac disease is far less than deterministic. Most who have the potential never develop the disease. In order for the potential to develop celiac disease to turn into active celiac disease, some triggering stress event or events must "turn on" the latent genes. This triggering stress event can be a viral infection, some other medical event, or even prolonged psychological/emotional trauma. This part of the equation is difficult to quantify but this is the epigenetic dimension of the disease. Epigenetics has to do with the influence that environmental factors and things not coded into the DNA itself have to do in "turning on" susceptible genes. And this is why celiac disease can develop at any stage of life. Celiac disease is an autoimmune condition (not a food allergy) that causes inflammation in the lining of the small bowel. The ingestion of gluten causes the body to attack the cells of this lining which, over time, damages and destroys them, impairing the body's ability to absorb nutrients since this is the part of the intestinal track responsible for nutrient absorption and also causing numerous other food sensitivities such as dairy/lactose intolerance. There is another gluten-related disorder known as NCGS (Non Celiac Gluten Sensitivity or just, "gluten sensitivity") that is not autoimmune in nature and which does not damage the small bowel lining. However, NCGS shares many of the same symptoms with celiac disease such as gas, bloating, and diarrhea. It is also much more common than celiac disease. There is no test for NCGS so, because they share common symptoms, celiac disease must first be ruled out through formal testing for celiac disease. This is where your husband is right now. It should also be said that some experts believe NCGS can transition into celiac disease. I hope this helps.
    • Judy M
      My husband has had lactose intolerance for his entire life (he's 68 yo).  So, he's used to gastro issues. But for the past year he's been experiencing bouts of diarrhea that last for hours.  He finally went to his gastroenterologist ... several blood tests ruled out other maladies, but his celiac results are suspect.  He is scheduled for an endoscopy and colonoscopy in 2 weeks.  He was told to eat "gluten free" until the tests!!!  I, and he know nothing about this "diet" much less how to navigate his in daily life!! The more I read, the more my head is spinning.  So I guess I have 2 questions.  First, I read on this website that prior to testing, eat gluten so as not to compromise the testing!  Is that true? His primary care doctor told him to eat gluten free prior to testing!  I'm so confused.  Second, I read that celiac disease is genetic or caused by other ways such as surgery.  No family history but Gall bladder removal 7 years ago, maybe?  But how in God's name does something like this crop up and now is so awful he can't go a day without worrying.  He still works in Manhattan and considers himself lucky if he gets there without incident!  Advice from those who know would be appreciated!!!!!!!!!!!!
    • Scott Adams
      You've done an excellent job of meticulously tracking the rash's unpredictable behavior, from its symmetrical spread and stubborn scabbing to the potential triggers you've identified, like the asthma medication and dietary changes. It's particularly telling that the rash seems to flare with wheat consumption, even though your initial blood test was negative—as you've noted, being off wheat before a test can sometimes lead to a false negative, and your description of the other symptoms—joint pain, brain fog, stomach issues—is very compelling. The symmetry of the rash is a crucial detail that often points toward an internal cause, such as an autoimmune response or a systemic reaction, rather than just an external irritant like a plant or mites. I hope your doctor tomorrow takes the time to listen carefully to all of this evidence you've gathered and works with you to find some real answers and effective relief. Don't be discouraged if the rash fluctuates; your detailed history is the most valuable tool you have for getting an accurate diagnosis.
    • Scott Adams
      In this case the beer is excellent, but for those who are super sensitive it is likely better to go the full gluten-free beer route. Lakefront Brewery (another sponsor!) has good gluten-free beer made without any gluten ingredients.
    • trents
      Welcome to the forum, @catsrlife! Celiac disease can be diagnosed without committing to a full-blown "gluten challenge" if you get a skin biopsy done during an active outbreak of dermatitis herpetiformis, assuming that is what is causing the rash. There is no other known cause for dermatitis herpetiformis so it is definitive for celiac disease. You would need to find a dermatologist who is familiar with doing the biopsy correctly, however. The samples need to be taken next to the pustules, not on them . . . a mistake many dermatologists make when biopsying for dermatitis herpetiformis. 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.