Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Help Understanding Genetic Test Results

cblack

Recommended Posts

cblack Apprentice
cblack
Posted

Please, if anyone can help me to understand these test results from genetic testing on my son:

Molecular Analysis of DQA1 Genotype:

0501 (HLA-DQ2) Gluten Sensitivity Positive: Yes

Molecular Analysis of DQB1 Genotype:

0201 (HLA-DQ2) Gluten Sensitivity Positive: Yes

0202 (HLA-DQ2) Gluten Sensitivity Positive: Yes

Genetic Analysis of your HLA-DQ genes reveals that you have three positive gene alleles for gene gluten sensitivity.

We had genetic testing done on him because I was diagnosed with celiac disease three months ago after 13 years of numerous gastro problesm. He doesn't have very many gastro issues other than being lactose intolerant. He does however have issues with gaining weight (very thin but eats like a horse!), brain fog, diagnosed as a child with ADD, canker sores, and fatigue. Based off the genetic testing, would it be prudent to go ahead and find a doctor to do the celiac blood testing panel? Thank you in advance for any help understanding the above genetic numbers! This board has been a blessing!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Kay DH Apprentice
Kay DH
Posted

People with gluten intolerance almost always have the HLA-DQ2 and (or) DQ8 genetic markers. Absence of both of these makers indicated a very low chance of having Celiac or DH. Their presence indicated a greater potential of Celiac than for the general populace. Celiac panel blood test is a very good idea; make sure he is being glutened for some weeks before the test or he can get a false negative. I tested negative on all but my genetic tests (HLA-DQ8), but I was on gluten, and elimination of this nasty molecule cured my GI, mood, stiffness, and other problems. It is a hard choice to go gluten-free and follow the diet, but important to life.

Korwyn Explorer
Korwyn
Posted

Please, if anyone can help me to understand these test results from genetic testing on my son:

Molecular Analysis of DQA1 Genotype:

0501 (HLA-DQ2) Gluten Sensitivity Positive: Yes

Molecular Analysis of DQB1 Genotype:

0201 (HLA-DQ2) Gluten Sensitivity Positive: Yes

0202 (HLA-DQ2) Gluten Sensitivity Positive: Yes

Genetic Analysis of your HLA-DQ genes reveals that you have three positive gene alleles for gene gluten sensitivity.

We had genetic testing done on him because I was diagnosed with celiac disease three months ago after 13 years of numerous gastro problesm. He doesn't have very many gastro issues other than being lactose intolerant. He does however have issues with gaining weight (very thin but eats like a horse!), brain fog, diagnosed as a child with ADD, canker sores, and fatigue. Based off the genetic testing, would it be prudent to go ahead and find a doctor to do the celiac blood testing panel? Thank you in advance for any help understanding the above genetic numbers! This board has been a blessing!

Just out of curiosity, what company did your testing? I'm looking to get retested to see what is on the DQA and also to validate the other lab I used.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Scott Adams
      - Scott Adams commented on Scott Adams's article in Cookies
      2

      Gluten-Free Cranberry Pistachio Snowball Cookies

      This article may help:
    2. Judy Wysocki
      - Judy Wysocki commented on Scott Adams's article in Cookies
      2

      Gluten-Free Cranberry Pistachio Snowball Cookies

      What can I substitute for almond flour? I plan on not doing the nuts either. I'm allergic to nuts.
    3. Scott Adams
      0

      Raspberry Dark Chocolate Gluten-Free Buckwheat Brownies

    4. Scott Adams
      - Scott Adams replied to JoJo0611's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      CT with contrast.

      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests. Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.
    5. Scott Adams
      - Scott Adams replied to Shellly's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      New labs are now very elevated

      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times...
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      132,201
    • Most Online (within 30 mins)
      7,748
    Judy Wysocki
    Newest Member
    Judy Wysocki
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      CT with contrast.

      By Scott Adams · Posted

      They may want to also eliminate other possible causes for your symptoms/issues and are doing additional tests.  Here is info about blood tests for celiac disease--if positive an endoscopy where biopsies of your intestinal villi are taken to confirm is the typical follow up.    
    • Scott Adams
      New labs are now very elevated

      By Scott Adams · Posted

      In the Europe the new protocol for making a celiac disease diagnosis in children is if their tTg-IgA (tissue transglutaminase IgA) levels are 10 times or above the positive level for celiac disease--and you are above that level. According to the latest research, if the blood test results are at certain high levels that range between 5-10 times the reference range for a positive celiac disease diagnosis, it may not be necessary to confirm the results using an endoscopy/biopsy: Blood Test Alone Can Diagnose Celiac Disease in Most Children and Adults TGA-IgA at or Above Five Times Normal Limit in Kids Indicates Celiac Disease in Nearly All Cases No More Biopsies to Diagnose Celiac Disease in Children! May I ask why you've had so many past tTg-IgA tests done, and many of them seem to have been done 3 times during short time intervals?    
    • trents
      Chances of being coeliac

      By trents · Posted

      @JettaGirl, "Coeliac" is the British spelling of "celiac". Same disease. 
    • JettaGirl
      Chances of being coeliac

      By JettaGirl · Posted

      This may sound ridiculous but is this supposed to say Celiacs? I looked up Coeliacs because you never know, there’s a lot of diseases related to a disease that they come up with similar names for. It’s probably meant to say Celiacs but I just wanted to confirm.
    • JoJo0611
      CT with contrast.

      By JoJo0611 · Posted

      I was told it was to see how much damage has been caused. But just told CT with contrast not any other name for it. 
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.