Could Elevated Sgpt And Normal Sgot Mean Celiac?

[Jill2011]

I have been having various symptoms that seem consistent w/ Celiac. I am waiting for my Celiac test to come back, but in the meantime I was told that my SGPT was elevated while my SGOT was normal. My doctor said that those results point to alcohol abuse, but I only drink in moderation (rarely more than 1 glass). Could these values point to Celiac?

[Jill2011]

I have been having various symptoms that seem consistent w/ Celiac. I am waiting for my Celiac test to come back, but in the meantime I was told that my SGPT was elevated while my SGOT was normal. My doctor said that those results point to alcohol abuse, but I only drink in moderation (rarely more than 1 glass). Could these values point to Celiac?

Whoops - I meant elevated SGOT and normal SGPT.

[JoshB]

Yes, but that doesn't mean much. There are many, many things that occur with celiac disease. It's a "great mimicker".

[Jill2011]

Yes, but that doesn't mean much. There are many, many things that occur with celiac disease. It's a "great mimicker".

My doctor seems to think that the only answer is alcohol abuse, which I assured her is not happening, but I'm not sure she believed me.

[pain*in*my*gut]

My doctor seems to think that the only answer is alcohol abuse, which I assured her is not happening, but I'm not sure she believed me.

There are many, many reasons for elevated liver enzymes. Yes, alcohol abuse is one possibility, but other causes are obesity, diabetes, certain medications and viruses. Celiac disease and the other inflammatory bowel diseases can also cause liver enzyme abnormalities, but they usually are not a severe as the other causes.

How elevated was your SGOT (also know as AST)? SGPT is also know as ALT, so if you want to google it you won't get confused between the different terminology.

[Jill2011]

There are many, many reasons for elevated liver enzymes. Yes, alcohol abuse is one possibility, but other causes are obesity, diabetes, certain medications and viruses. Celiac disease and the other inflammatory bowel diseases can also cause liver enzyme abnormalities, but they usually are not a severe as the other causes.

How elevated was your SGOT (also know as AST)? SGPT is also know as ALT, so if you want to google it you won't get confused between the different terminology.

Thank you for your response and terminology advice

SGOT: 51

SGPT: 28

I'm generally slightly underweight for my height, and I've lost 12 lbs over the past 4-6 weeks (not purposefully). I'm not a diabetic, and I just had an upper and lower GI exam with only showed GERD.

I also have elevated MCV: 106.7

Up until about 3 months ago I felt completely healthy, but since then I've had constipation, diarrhea, brain fog, irritability, stomach pain, and the weigh loss. Also I'm premenopausal and was diagnosed with osteoporosis several years ago.

[pain*in*my*gut]

Thank you for your response and terminology advice

SGOT: 51

SGPT: 28

I'm generally slightly underweight for my height, and I've lost 12 lbs over the past 4-6 weeks (not purposefully). I'm not a diabetic, and I just had an upper and lower GI exam with only showed GERD.

I also have elevated MCV: 106.7

Up until about 3 months ago I felt completely healthy, but since then I've had constipation, diarrhea, brain fog, irritability, stomach pain, and the weigh loss. Also I'm premenopausal and was diagnosed with osteoporosis several years ago.

Your AST is not that high (5-40 is usual normal range). That could totally be from a random virus (this happened to me about a year ago...my doc checked it again the next month and it was normal).

Your doc needs to properly evaluate the cause of the elevated AST instead of just jump to conclusions. I would be pretty angry and be looking for a new doc if I were you!

Check out this link:

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Regarding the MCV, that indicates that you have macrocytic anemia. This can be caused by Vit B12 and or folic acid deficiency, as well as alcohol abuse (which is probably why your doc is stuck on the alcohol thing). It can also be cause by Celiac!

Keep us posted on your Celiac results. Hopefully you will get some answers...sounds like you have been pretty miserable...

[Skylark]

We see a fair number of pre-diagnosis celiacs on the board with elevated liver enzymes. You might print this for your doctor, preferably a new one! Did they happen to take any biopsies on the upper GI exam, or did this idiot doctor miss doing that too?

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If your celiac test comes back negative it's still worth trying the gluten-free diet. You might not have antibodies in your blood this early into the disease, or you might be gluten intolerant instead. There is also no harm in taking a B-complex supplement if you haven't started one already.