Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Please Tell Me About The Link Between Lisinopril And Celiac

WitsEnd

Recommended Posts

WitsEnd Rookie
WitsEnd
Posted

Hi. I am new here. I've been struggling with an undiagnosed illness over the past year and a half and been to every specialist in town without a firm diagnosis. Actually, every time a see a new doctor I have a new diagnosis: migraines, high blood pressure, anxiety, IBS, severe Vit D deficiency, slight anemia, and so on, but nothing seems to really be the right diagnosis.

My symptoms: sharp headaches, migraines, diarrhea, chest pains, stomach pains after eating, dizziness, vertigo, swollen lymph nodes, blurry vision, tingling in jaw, foggy head, heavy chest, severe gas, tight/painful stomach when I wake, pain in sides/kidney area/sides, sore throat.

I recently heard of a connection between Lisinopril and Celiac, and it just occured to me I started taking that about the same time the symptoms started. I stopped taking it for about a month and still felt bad, but I was still eating gluten during that time. I am back on Lisinopril again but now I'm concerned that's the problem. I can't seem to find much information on the internet though linking the two.

I did have a celiac blood panel, but in reading other threads I think I may not have received the full test. My results:

Anti Endomysial, IgA Negative

Anti Gliadin, IgA 6

Anti Gliadin, IgG 3

Anti tTransglutaminase, IgA 5

Anti tTrasglutaminase, IgG Negative

I have not yet had an EGD. That was the plan but it has taken a while to have this done and in the meantime I decided to try eating gluten free. I have felt remarkably better and most of my symptoms have gone or at least been greatly reduced. I now realize being gluten free will affect the EGD, but I started it on a whim and it was so successful I'm not sure I want to go back on gluten to get an accurate test.

I would appreciate any help you could give me.

Thanks!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


mommida Enthusiast
mommida
Posted

By removing gluten from your diet, you may have eliminated your chances of being diagnosed Celiac or Eosinophilic Esophagitus. Your symptom list fits both disorders.

roxieb73 Contributor
roxieb73
Posted

As far as I know there is NO link to lisinopril and Celiac. (I work in pharmacy) Celiac is a genetic disease. However your symptoms do sound a lot like Celiac. How long have you been Gluten free? I might or might not have an impact. There are folks with much more experiecne that will chime in. Sorry still new here and figuring it out myself.

Roxie

WitsEnd Rookie
WitsEnd
Posted
  • Author

Unfortunately I have been gluten free for 6 Weeks. I had already had the blood test and I honestly didnt think the diet would be that successful in eliminating my symptoms so I thought it was ok to try. Now im not sure I want to try gluten again for the testing.

However, I would like to stop lisinopril if that's a problem.

roxieb73 Contributor
roxieb73
Posted

Unfortunately I have been gluten free for 6 Weeks. I had already had the blood test and I honestly didnt think the diet would be that successful in eliminating my symptoms so I thought it was ok to try. Now im not sure I want to try gluten again for the testing.

However, I would like to stop lisinopril if that's a problem.

Oh no you have a bit of a delima. :( You need to get your doctor to change your lisinopril to something else. As far as the Gluten free. It is not fun AT ALL to go back on it. How important is the testing to you?

Bubba's Mom Enthusiast
Bubba's Mom
Posted

I was at the Mayo clinic in May. I talked with Dr. Murry the head of the GI/Celiac dept. He said they're looking into what medications Celiacs have been on in the past to see if they can find links to Celiac-certain meds.

I had been on Lisinopril but it made me cough and clear my throat a lot. I went off it because of that. My sister had even more severe reactions to it. He said a lot of people don't tolerate it well. It's one that they are looking at, but so far they are still researching it.

Another thing that could be a possibility for you with migraines,etc. is a small intestine bacterial overgrowth. (SIBO) I was tested and was told I had a severe overgrowth. When bacteria is where it shouldn't be it grabs the nutrients from your food and emits toxins that get into your blood stream. Dr. Murry suspected it when I didn't improve much on a very strict gluten-free diet. He said reacting to additional foods is a tip-off too.

If you've taken acid reducing drugs, or PPIs, it's a good idea to ask for hydrogen breath test for SIBO. Acid is one of the things that helps keep bacteria in check. Be sure to take probiotics if you aren't currently. They crowd out the bad guys and aid in digestion. Very important to a distressed gut.

WitsEnd Rookie
WitsEnd
Posted
  • Author

Thank you for the info. I am not sure how important the testing is to me. I think I accidentally ate gluten yesterday or today because I'm feeling really sick right now. All the symptoms are coming back very strong. And I was doing so well! Finally feeling good for the first time in months, I almost forgot how sick I was. There's no way I could go back to being sick every day...this is miserable!

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. trents
      - trents replied to SilkieFairy's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      4

      IBS-D vs Celiac

      No coincidence. Recent revisions to gluten challenge guidelines call for the daily consumption of at least 10g of gluten (about the amount in 4-6 slices of wheat bread) for a minimum of 3 weeks. If possible, I would extend that two weeks to ensure valid testing.
    2. SilkieFairy
      - SilkieFairy replied to SilkieFairy's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      4

      IBS-D vs Celiac

      Thank you both for the replies. I decided to bring back gluten so I can do the blood test. Today is Day #2 of the Challenge. Yesterday I had about 3 slices of whole wheat bread and I woke up with urgent diarrhea this morning. It was orange, sandy and had the distinctive smell that I did not have when I was briefly gluten free. I don't know if it's a...
    3. knitty kitty
      - knitty kitty replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      @Jane02, I hear you about the kale and collard greens. I don't do dairy and must eat green leafies, too, to get sufficient calcium. I must be very careful because some calcium supplements are made from ground up crustacean shells. When I was deficient in Vitamin D, I took high doses of Vitamin D to correct the deficiency quickly. This is safe...
    4. Jane02
      - Jane02 replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      Thank you so much @knitty kitty for this insightful information! I would have never considered fractionated coconut oil to be a potential source of GI upset. I will consider all the info you shared. Very interesting about the Thiamine deficiency. I've tracked daily averages of my intake in a nutrition software. The only nutrient I can't consistently...
    5. knitty kitty
      - knitty kitty replied to Jane02's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      Hello, @Jane02, I take Naturewise D 3. It contains olive oil. Some Vitamin D supplements, like D Drops, are made with fractionated coconut oil which can cause digestive upsets. Fractionated coconut oil is not the same as coconut oil used for cooking. Fractionated coconut oil has been treated for longer shelf life, so it won't go bad in the...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,336
    • Most Online (within 30 mins)
      7,748
    Jeffrey Yeres
    Newest Member
    Jeffrey Yeres
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • trents
      IBS-D vs Celiac

      By trents · Posted

      No coincidence. Recent revisions to gluten challenge guidelines call for the daily consumption of at least 10g of gluten (about the amount in 4-6 slices of wheat bread) for a minimum of 3 weeks. If possible, I would extend that two weeks to ensure valid testing.
    • SilkieFairy
      IBS-D vs Celiac

      By SilkieFairy · Posted

      Thank you both for the replies. I decided to bring back gluten so I can do the blood test. Today is Day #2 of the Challenge. Yesterday I had about 3 slices of whole wheat bread and I woke up with urgent diarrhea this morning. It was orange, sandy and had the distinctive smell that I did not have when I was briefly gluten free. I don't know if it's a coincidence, but the brain fog is back and I feel very tired.   
    • knitty kitty
      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      By knitty kitty · Posted

      @Jane02, I hear you about the kale and collard greens.  I don't do dairy and must eat green leafies, too, to get sufficient calcium.  I must be very careful because some calcium supplements are made from ground up crustacean shells.  When I was deficient in Vitamin D, I took high doses of Vitamin D to correct the deficiency quickly.  This is safe and nontoxic.  Vitamin D level should be above 70 nmol/L.  Lifeguards and indigenous Pacific Islanders typically have levels between 80-100 nmol/L.   Levels lower than this are based on amount needed to prevent disease like rickets and osteomalacia. We need more thiamine when we're physically ill, emotionally and mentally stressed, and if we exercise like an athlete or laborer.  We need more thiamine if we eat a diet high in simple carbohydrates.  For every 500 kcal of carbohydrates, we need 500-1000 mg more of thiamine to process the carbs into energy.  If there's insufficient thiamine the carbs get stored as fat.  Again, recommended levels set for thiamine are based on minimum amounts needed to prevent disease.  This is often not adequate for optimum health, nor sufficient for people with absorption problems such as Celiac disease.  Gluten free processed foods are not enriched with vitamins like their gluten containing counterparts.  Adding a B Complex and additional thiamine improves health for Celiacs.  Thiamine is safe and nontoxic even in high doses.  Thiamine helps the mitochondria in cells to function.  Thiamine interacts with each of the other B vitamins.  They are all water soluble and easily excreted if not needed. Interesting Reading: Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet https://pubmed.ncbi.nlm.nih.gov/19154566/ Safety and effectiveness of vitamin D mega-dose: A systematic review https://pubmed.ncbi.nlm.nih.gov/34857184/ High dose dietary vitamin D allocates surplus calories to muscle and growth instead of fat via modulation of myostatin and leptin signaling https://pubmed.ncbi.nlm.nih.gov/38766160/ Safety of High-Dose Vitamin D Supplementation: Secondary Analysis of a Randomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/31746327/ Vitamins and Celiac Disease: Beyond Vitamin D https://pmc.ncbi.nlm.nih.gov/articles/PMC11857425/ Investigating the therapeutic potential of tryptophan and vitamin A in modulating immune responses in celiac disease: an experimental study https://pubmed.ncbi.nlm.nih.gov/40178602/ Investigating the Impact of Vitamin A and Amino Acids on Immune Responses in Celiac Disease Patients https://pmc.ncbi.nlm.nih.gov/articles/PMC10814138/
    • Jane02
      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      By Jane02 · Posted

      Thank you so much @knitty kitty for this insightful information! I would have never considered fractionated coconut oil to be a potential source of GI upset. I will consider all the info you shared. Very interesting about the Thiamine deficiency.  I've tracked daily averages of my intake in a nutrition software. The only nutrient I can't consistently meet from my diet is vitamin D. Calcium is a hit and miss as I rely on vegetables, dark leafy greens as a major source, for my calcium intake. I'm able to meet it when I either eat or juice a bundle of kale or collard greens daily haha. My thiamine intake is roughly 120% of my needs, although I do recognize that I may not be absorbing all of these nutrients consistently with intermittent unintentional exposures to gluten.  My vitamin A intake is roughly 900% (~6400 mcg/d) of my needs as I eat a lot of sweet potato, although since it's plant-derived vitamin A (beta-carotene) apparently it's not likely to cause toxicity.  Thanks again! 
    • knitty kitty
      Desperately need a vitamin D supplement. I've reacted to most brands I've tried.

      By knitty kitty · Posted

      Hello, @Jane02,  I take Naturewise D 3.  It contains olive oil.   Some Vitamin D supplements, like D Drops, are made with fractionated coconut oil which can cause digestive upsets.  Fractionated coconut oil is not the same as coconut oil used for cooking.  Fractionated coconut oil has been treated for longer shelf life, so it won't go bad in the jar, and thus may be irritating to the digestive system. I avoid supplements made with soy because many people with Celiac Disease also react to soy.  Mixed tocopherols, an ingredient in Thornes Vitamin D, may be sourced from soy oil.  Kirkland's has soy on its ingredient list. I avoid things that might contain or be exposed to crustaceans, like Metagenics says on its label.  I have a crustacean/shellfish/fish allergy.  I like Life Extension Bioactive Complete B Complex.  I take additional Thiamine B 1 in the form Benfotiamine which helps the intestines heal, Life Extension MegaBenfotiamine. Thiamine is needed to activate Vitamin D.   Low thiamine can make one feel like they are getting glutened after a meal containing lots of simple carbohydrates like white rice, or processed gluten free foods like cookies and pasta.   It's rare to have a single vitamin deficiency.  The water soluble B Complex vitamins should be supplemented together with additional Thiamine in the form Benfotiamine and Thiamine TTFD (tetrahydrofurfuryl disulfide) to correct subclinical deficiencies that don't show up on blood tests.  These are subclinical deficiencies within organs and tissues.  Blood is a transportation system.  The body will deplete tissues and organs in order to keep a supply of thiamine in the bloodstream going to the brain and heart.   If you're low in Vitamin D, you may well be low in other fat soluble vitamins like Vitamin A and Vitamin K. Have you seen a dietician?
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.