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    • knitty kitty
      @SB04, Have you been checked for B12 deficiency?  A deficiency in Vitamin B12 will cause hives and also raise the tTg 3 IgG level, even in people without Celiac Disease.   You can have B12 deficiency without having Celiac Disease.   All eight B vitamins work together.  Do not supplement just a single B vitamin.   Best wishes.
    • Idnam
      I've just had 24 hr ECG monitoring but I am convinced the problem with my heart arythma  is due to Histamine intolerance. I was making and loving L reuteri yogurt, supposed to get rid of sibo, I was also having, on a daily basis, kefir, sauerkraut and loads of spinach plus Avacado. Bananas and cheese have long  been off my list of safe foods as I was having a sort of allergic reaction after eating them and my accupuncturist said I had a heart arrythma.  After the yogurt fest mentioned above, I had a racing heart rate and think I must have had far too many Histamine producing foods. Apparently celiacs have too much histamine in their system anyway and I was, on a daily basis, eating very high histamine foods. I have cut them out of my diet and now eat only low histamine foods and I take quercin so the heart rate has slowed and the thudding I was getting at 4am has gone so I think I am right. The only symptom I  had for celiac disease (3yrs since diagnosed)  was acid reflux and the only thing that stopped the chest pain it gave me was the PPi Rinitidine  an H2 antagonist, to reduce stomach acid, (which high histamine causes) because it nuetralised the histamine!!  I told my doctor this and  he agreed with me and was delightfully shocked by my research,  (btw what would we celiacs do without google?) so I took a Famotadine, amore up to date H2 ppi for a couple of nights and then reduced my histamine intake, now awaiting results re the  ECG..............I seem to have lost my ability to spell, sorry...............      
    • Russ H
      The problem with a a multiple screening test like this is that it is likely to generate at least one result that is outside the normal range in a healthy person leading to futile investigations. The pathogenesis of dermatitis herpetiformis makes it unlikely that someone would have raised IgA-tTG3 but not raised IgA-tTG2. Suspected dermatitis herpetiformis should be referred to a specialist for diagnosis. dermatitis herpetiformis causes a specific rash and symptoms - not merely hives. https://bestpractice.bmj.com/topics/en-gb/3000326
    • SB04
      Thanks! I don't think it was a total IGA test, it was called "Array 3X - Wheat/Gluten Proteome Reactivity & Autoimmunity" and it tested a bunch of wheat proteins and transglutaminase for both IgG and IGAs.  
    • trents
      Welcome to the forum, @SB04! Let's cut to the chase. Did they run a tTG-IGA and a total IGA? Total IGA goes by many names but it checks for IGA deficiency. If you are IGA deficient, IGA test scores will be artificially low and it can result in false negatives. The tTG-IGA is the centerpiece of celiac disease antibody testing.  Dermatitis herpetiformis is the epidermal expression of celiac disease. Most who have dermatitis herpetiformis also have damage happening to the small bowel lining as well but a small percentage do not. But dermatitis herpetiformis has a characteristic appearance to it, with the rash bumps having pustules in the center. It is also accompanied by a very uncomfortable itch. From what you describe, your rash doesn't sound like dermatitis herpetiformis. The IGG antibody tests are not quite as specific for celiac disease as are the IGA tests but they aren't terrible either. This may be helpful:   
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