Jump to content
  • Sign Up
Celiac.com Sponsor:

Celiac.com Sponsor:

  • Join Our Community!

    Get help in our celiac / gluten-free forum.

  • Jefferson Adams

    New Screening Method Offers Faster and Easier Detection of Celiac Antibodies

    Jefferson Adams

    Reviewed and edited by a celiac disease expert.

      New method for screening celiac disease offer easier and faster detection of celiac antibodies.

    Caption: Image: CC BY 2.0--NIHClinicalCenter

    Celiac.com 12/11/2019 - While celiac disease affects an estimated 1% of people worldwide, more than 90% of people with the disease remain undiagnosed. Current celiac disease protocols call for screening patients with gastrointestinal symptoms or other autoimmune diseases, along with any first-degree relatives of celiac patients.

    However, current screening usually involves a trip to the doctor's office for a blood test that measures levels of celiac-specific antibodies. That simple trip can be a barrier to screening, and thus to treatment and healing. Even in more developed countries, more than half of celiacs are unaware of their disease.

    Celiac.com Sponsor:

    Rapid diagnosis and treatment of celiac disease is important, because delayed diagnosis often means persistent symptoms even after treatment, along with impaired quality of life.

    One solution lies in point-of-care (POC) testing, which moves medical testing from central laboratories directly to the place where the patient is receiving care.

    To assist in rapid and reliable disease screening, researchers from the University of Helsinki have developed a novel diagnostic method coined RFS (Rapid FRET serodiagnostics) for the rapid on-site measurement of antibodies from patient samples. This technology could revolutionize blood screening for microbial, autoimmune and allergic disorders. That same team recently applied their new diagnostic method to celiac disease screening.

    Fast and Easy Detection of Celiac Antibodies

    The research team took blood samples from 35 children and 35 adults with celiac disease. They also took samples from healthy control subjects. They measured samples with the new test method, and compared results with two current methods.

    According to Juuso Rusanen, MD, "The performance of the test was comparable to that of current methods, [which] involves transporting the sample to a central laboratory and a multi-step procedure taking hours."

    The new method provides accurate results "in less than half an hour by simply combining the sample and a reagent mix, waiting for a while and reading the result."

    Rusanen says that the team hopes that the new method can "lower the threshold for screening of celiac disease and thus help overcome the vast under-diagnosis of this relatively common condition."

    This test marks the first time their method has been used for diagnosing an autoimmune disease. The promising results invite the development of similar diagnostic tests aimed at other autoimmune diseases, says Rusanen.

    Read more at Eurekalert.com

    User Feedback

    Recommended Comments

    Join the conversation

    You are posting as a guest. If you have an account, sign in now to post with your account.
    Note: Your post will require moderator approval before it will be visible.

    Add a comment...

    ×   Pasted as rich text.   Paste as plain text instead

      Only 75 emoji are allowed.

    ×   Your link has been automatically embedded.   Display as a link instead

    ×   Your previous content has been restored.   Clear editor

    ×   You cannot paste images directly. Upload or insert images from URL.

  • About Me

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University, and has authored more than 2,500 articles on celiac disease. His coursework includes studies in science, scientific methodology, biology, anatomy, medicine, logic, and advanced research. He previously served as SF Health News Examiner for Examiner.com, and devised health and medical content for Sharecare.com. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of the book "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

  • Related Articles

    Jefferson Adams
    Celiac.com 04/25/2017 - A recent issue of JAMA, the US Preventive Services Task Force (USPSTF) critically examines screening for celiac disease in asymptomatic adults, adolescents, and children.
    Celiac disease exhibits a broad spectrum of symptoms, from subtle or no symptoms to severe malabsorption. Celiac diagnoses have increased significantly over the past few decades, in...

    Jefferson Adams
    Celiac.com 07/03/2018 - The vast majority of celiac disease remain undiagnosed, and clinical testing is usually done on a case by case basis. Factor in vague or atypical symptoms, and you have a recipe for delayed diagnosis and unnecessary suffering. What determines who gets tested, and are current screening methods working?
    A team of researchers recently set out to assess ...

    Jefferson Adams
    Celiac.com 04/01/2019 - Over the years, testing for celiac disease has become easier and more reliable. There are a number of home tests for celiac disease antibodies, and a number of reasons people might want to test for celiac disease at home. Those reasons include privacy, cost, and convenience. There are two kinds of tests for celiac disease, antibody tests and genetic tests....

  • Celiac.com Sponsor:

  • Forum Discussions

    Keight, Be very hopeful and expectant of your ability to build once you recover. I was diagnosed in 1995 and began running after 6 months of recovery. After 18 months I was cut and could run 15 miles no problem - I became bored after ...
    The grief... Oh yeah, it is real. I mourn for the opportunities I knocked back food wise, for I was one of those women you spoke of! I avoided fattening foods, and I had no guidance on how to eat, and THEN I took up body building in 2010....
    Thank you for noticing that. I did pack as much AN-PEP as possible into the capsule without other ingredients except a flow agent to allow the capsule to be filled better and a small percentage of a food grade acid that has proven to greatly...
  • Create New...