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Amiah

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Help!!


Amiah

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Took six-year-old two pediatrician complaining a frequent stomach aches. Did blood testing for celiac and she is IGA deficient. The next thing they tested for was tissue transglutaminase antibody igG and this came back positive with a normal range less than 15, her number was 87.9 so they referred us to a Gastro doctor. The gas doctor said that with this number there is a 99% chance of celiac, but they would like to do a scope to verify. We did a scope and everything looked good and they took samples and all came back negative for celiac. What should we do next? Why would her celiac test come back so positive in the blood Test? 

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trents

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Welcome to the celiac.com community, @Amiah!

First of all, you would do well to post your question in one of the appropriate community forums rather than in a blog. It will get more attention that way.

Now as to your question, there are some other things that can cause elevated igg antibodies besides celiac disease. Various infections, mostly. For instance, candida albicans. But the odds are it is nascent celiac disease and there has not been enough time for damage to the lining of the small bowel to manifest itself. 

At this point, it might be wise to trial the gluten free diet and see if her symptoms improve. If they do, she either has celiac disease or NCGS (Non Celiac Gluten Sensitivity). The GI symptoms of the two overlap significantly. NCGS does not damage the lining of the small bowel and does not have an autoimmune component so there are not tests for it yet. Celiac disease must first be ruled out. The other thing you can do is to have genetic testing done to see if she carries either of the two primary genes known to provide the potential to develop celiac disease. Almost 40% of the population have one or both of the genes but only about 1% of the population develops celiac disease so it is not really a diagnostic test so much as it is a "rule out celiac disease" test.

I hope this helps.

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