Celiac.com 02/04/2013 - Ever wonder what happens to all those celiac disease patients who volunteer to do a gluten-challenge in the name of science? Well, the short answer is that they likely suffer, and may incur gut damage, at least in the short term.
A team of researchers looking for ways to reduce or eliminate that problem recently conducted a study using larazotide acetate, a first-in-class oral peptide that prevents tight junction opening, and may reduce gluten uptake and associated problems.
The research team included C. P. Kelly, P. H. R. Green, J. A. Murray, A. DiMarino, A. Colatrella, D. A. Leffler, T. Alexander, R. Arsenescu, F. Leon, J. G. Jiang, L. A. Arterburner, B. M. Paterson, R. N. and Fedorak. They are affiliated with the Celiac Center of Beth Israel Deaconess Medical...
Celiac.com 01/01/2014 - By enabling researchers to link antibodies with certain diseases, a new method could help uncover and confirm environmental triggers for diseases such as celiac and autism.
The researchers have two goals, according to professor Patrick Daugherty, a researcher with the department of chemical engineering and the Center for BioEngineering at University of California, Santa Barbara.
First, they want to create diagnostic tests for diseases for which there are currently no blood tests. Next, they want to figure out what causes the diseases.
The process works by mining an individual’s immunological memory—a veritable catalog of the pathogens and antigens encountered by his or her immune system
Every time we encounter a pathogen, our bodies mou...
Celiac.com 04/20/2015 - Microscopic enteritis is an inflammatory condition of the small bowel that leads to gastrointestinal symptoms, nutrient and micronutrient deficiency. The idea of microscopic enteritis arose from mucosal changes associated with celiac disease and was originally described in detail by Marsh in 1992.
Microscopic enteritis is marked by microscopic or sub-microscopic abnormalities such as microvillus changes and enterocytic alterations in the absence of definite macroscopic changes using standard modern endoscopy.
A recent study addresses the need to characterize disorders with microscopic and submicroscopic features, currently regarded as functional or non-specific entities, to obtain further understanding of their clinical relevance.
Following the 5th International C...
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