Help interpreting tests?

[katief88]

Hi all

I'd be really grateful for any help interpreting this. I'm in UK and tests were ordered via alternative health practitioner who I'm no longer seeing - need to approach my general doctor to discuss but want some thoughts first. The only thing that was out of reference range was TTG IgG - is this enough by itself to be suggestive of celiac?

 

Many thanks

Alpha Gliadin 17-mer IgG 0.24 0.1-1.5
Alpha Gliadin 17-mer IgA 0.30 0.1-1.1
Gamma Gliadin 15-mer IgG 0.73 0.5-1.5
Gamma Gliadin 15-mer IgA 0.18 0.1-1.0
Omega Gliadin 17-mer IgG 0.30 0.3-1.2
Omega Gliadin 17-mer IgA 0.54 0.1-1.2
Glutenin 21-mer IgG 0.62 0.1-1.5
Glutenin 21-mer IgA 0.40 0.1-1.3

Transglutaminase-2 IgG 2.78 0.3-1.6
Transglutaminase-2 IgA 0.52 0.1-1.6

[squirmingitch]

Yes, as I understand it, the TTG IgG is is highly specific for celiac disease. This should be enough to go to your general doc with. You really need to have the complete celiac serum panel run. It is:

Anti-Gliadin (AGA) IgA
Anti-Gliadin (AGA) IgG
Anti-Endomysial (EMA) IgA
Anti-Tissue Transglutaminase (tTG) IgA
Deamidated Gliadin Peptide (DGP) IgA and IgG
Total Serum IgA 

 

Also can be termed this way:

Endomysial Antibody IgA
Tissue Transglutaminase IgA 
GLIADIN IgG
GLIADIN IgA
Total Serum IgA 
Deamidated Gliadin Peptide (DGP) IgA and IgG

 

IT IS VERY IMPORTANT THAT YOU CONTINUE EATING A REGULAR GLUTEN DIET UNTIL ALL TESTING HAS BEEN COMPLETED & THAT INCLUDES AN ENDOSCOPY IF THE DOC REQUIRES ONE TO DIAGNOSE. Otherwise you can get false negatives.