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Is Effective Enzyme Therapy for Celiac Disease Just Around The Corner?


Scott Adams

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Scott Adams Grand Master
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Enzyme Latiglutenase improves symptoms in some celiac patients, but which ones? Enzymes have shown some promise for treating celiac symptoms, but so far none has to improve histology or symptoms in celiac patients.

There are currently several efforts underway to develop successful commercial enzyme treatments for celiac disease. Efforts include looking at the digestive enzymes in plants, such as the papaya and star fruits, including such predatory plants, such as the pitcher plant.

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Victoria1234 Experienced

Shouldn't they be studying why celiacs who have been gluten-free for a year are still seropositive and having moderate to severe symptoms? 

It sounded like the pill was suppposed to be taken with meals that might have cc ? So why would they do a study where it's given with gluten-free meals? What would it be breaking down if the meal has no gluten? How would it help? I'm confused. But it's been a long day.

update

Just read some drug company is going to be selling these pills in 2023. I hope by then the poor celiacs still having bad problems are able to figure out why they are still hurting instead of having to take super expensive pills.

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    • JoJo0611
      Thank you this really helped. 
    • Samanthaeileen1
      Okay that is really good to know. So with that being positive and the other being high it makes sense she diagnosed her even without the endoscopy. So glad we caught it early. She had so many symptoms though that to me it was clear something was wrong.   yeah I think we had better test us and the other kids as well. 
    • GlorietaKaro
      One doctor suggested it, but then seemed irritated when I asked follow-up questions. Oh well—
    • trents
      @GlorietaKaro, your respiratory reactions to gluten make me wonder if there might also be an allergic (anaphylaxis) component at work here.
    • GlorietaKaro
      Thanks to both of you for your responses!  Sadly, even after several years of very strict gluten avoidance, I remember the symptoms well enough that I am too frightened to risk a gluten challenge— heartbeat and breathing problems are scary— Scott, thank you for the specific information— I will call around in the new year to see if I can find anyone. In the meantime, I will carry on has I have been— it’s working! Thanks also for the validation— sometimes I just feel crushed by disbelief. Not enough to make me eat gluten though—
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