Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Testing

lamusto

Recommended Posts

lamusto Newbie
lamusto
Posted

Just a quick observation and question about genetic testing, et.al.   I suspect that the tummy aches and diarrhea, a bit of ADD, over the course of over 7 years a few other things might be gluten problems, be they celiac disease or sensitivity.  Having read many comments about the use or uselessness of genetic testing, for me right now - it might be a good thing for the following reasons: first cost.  Due to reasons not worth going into at this point, much of it would come out of pocket until January.  Given the lower cost of the genetic testing, for me, would help me to narrow it down.  If he does not have the gene(s), then I can at least rule out a strong genetic component - which has it's use.  i realize that 40% or so had the gene(s) anyway, but it still helps me narrow the matter down.  That does not mean I cannot pursue further testing in January for blood antibody markers, etc. or other issues.  For me it's a start.  In light of that, is Enterolab reliable for that genetic testing?  I have seen various things about testing and it's reliability here which I understand.  I only was unclear about how reliable Enterolab was on the genetic testing.  Thanks in advance for your replies.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


kareng Grand Master
kareng
Posted

I wouldn't use Enterolab for anything.  The genetic tests are probably accurate but a lot of the other stuff they "test" for isn't medically accepted.

I got my genetic test from Quest.  But it seems to me that the basic Celiac blood panel (for antibodies) was about the same price as the genetic test.  You can call them and ask.

lamusto Newbie
lamusto
Posted
  • Author
2 minutes ago, kareng said:

I wouldn't use Enterolab for anything.  The genetic tests are probably accurate but a lot of the other stuff they "test" for isn't medically accepted.

I got my genetic test from Quest.  But it seems to me that the basic Celiac blood panel (for antibodies) was about the same price as the genetic test.  You can call them and ask.

I don't see a clear distinction between looking for antibodies verses looking for particular genes.  That part wasn't clear to me from reading their options.  I don't think  one can order the strict genetic test without the stool test.  But I submitted a question to them regarding that.  Thank you so much for your reply.  I will look into "Quest".

Gemini Experienced
Gemini
Posted
2 hours ago, lamusto said:

I don't see a clear distinction between looking for antibodies verses looking for particular genes.  That part wasn't clear to me from reading their options.  I don't think  one can order the strict genetic test without the stool test.  But I submitted a question to them regarding that.  Thank you so much for your reply.  I will look into "Quest".

Enterolab's gene testing is very reliable as gene testing is very common now and straightforward.  There is nothing questionable about it.  However, the other stool testing that they offer is not currently recognized as reliable and it isn't.  You cannot test for Celiac Disease utilizing stool samples, as of yet.  Maybe someday someone will come up with one that is peer reviewed and accepted by mainstream medicine but don't waste your money on it now. 

I had my gene testing done through Enterolab because doctors didn't do gene testing for Celiac 12 years ago when I was diagnosed. The blood work version done in hospitals was too expensive and they have antibody testing for Celiac.  I was diagnosed with Celiac through blood work from mainstream medical doctors, along with positive genetic tests from Enterolab. You should be able to order gene testing by itself through them but if they bundle it with other tests, I wouldn't bother.

 

ravenwoodglass Mentor
ravenwoodglass
Posted

In addition to the advice you have already gotten one caution. If you should happen to not have one of the 2 genes most commonly checked for it isn't for sure that you couldn't be celiac. There are rare cases, like mine, where people are diagnosed celiac but don't carry one of those two genes.  Getting a celiac panel is IMHO a better route to take.  Also if you have a low income or no insurance check with your local hospital as some will do a sliding fee scale on tests done through them.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Known1
      - Known1 replied to Known1's topic in Introduce Yourself / Share Stuff
      16

      Diagnosed Marsh stage 3C in January 2026

      @knitty kitty Holy smokes, that Life Extension B-Complex is burning me up. My multi-vitamin already has 25mg of Niacin. The b-complex adds another 100mg on top of that. My face, neck, and ears look like the Cardinal I use for my profile pic. I have been on the b-complex for 10-days now and it seems to get a bit worse with each passing day. I think I...
    2. HectorConvector
      - HectorConvector replied to HectorConvector's topic in Related Issues & Disorders
      319

      Terrible Neurological Symptoms

      Evidence from normoglycaemic studies shows that healthy people peak at ~1 hour, and they then return to baseline in 2–3 hours, not 1. CGM shows normal post-meal rises even in metabolically healthy subjects. Clinical tests use the 2-hour value to judge normal glucose clearance. Therefore the 1-hour-back-to-fasting claim contradicts both physiology and clinical d...
    3. HectorConvector
      - HectorConvector replied to HectorConvector's topic in Related Issues & Disorders
      319

      Terrible Neurological Symptoms

      I'm not sure what you're referring to as "normal" here - and is this something your doctor has mentioned (in bold)? As that isn't what any study or official information says. According to diabetes UK and the British Heart Foundation, normal fasting blood sugar is 4.9-5.4mmol/L. Normal by 2 hours from the start of a meal is anywhere below 7.8mmol/L. Random...
    4. HectorConvector
      - HectorConvector replied to HectorConvector's topic in Related Issues & Disorders
      319

      Terrible Neurological Symptoms

      My skin biopsy and MRI scan shows no signs of any type of nerve damage. Nothing consistent with demylination or peripheral nerve damage. On the contrary, the nerve function from the skin biopsy proved better than normal. I don't get any pins and needles or have any loss of nerve function. It's pain only. Thiamin I take is 100mg a day in tablet. I...
    5. knitty kitty
      - knitty kitty replied to HectorConvector's topic in Related Issues & Disorders
      319

      Terrible Neurological Symptoms

      @HectorConvector, My blood glucose level would spike after I ate. It wouldn't return to "normal" fasting blood glucose level for longer and longer. Blood glucose level should return to normal an hour after eating. Mine would take two hours, then three hours, then longer. So over night fasting blood tests wouldn't necessarily be very high until they...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,589
    • Most Online (within 30 mins)
      7,748
    Ozibella
    Newest Member
    Ozibella
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • Known1
      Diagnosed Marsh stage 3C in January 2026

      By Known1 · Posted

      @knitty kitty Holy smokes, that Life Extension B-Complex is burning me up.  My multi-vitamin already has 25mg of Niacin.  The b-complex adds another 100mg on top of that.  My face, neck, and ears look like the Cardinal I use for my profile pic.  I have been on the b-complex for 10-days now and it seems to get a bit worse with each passing day.  I think I am going to drop down to taking 1/2 of the serving size.  In other words, 1 capsule instead of 2.  Hopefully dropping to one does the trick. Have you noticed any side effects from that B-complex?  It is WAY over the daily recommended values: Thanks for your time, Known1
    • HectorConvector
      Terrible Neurological Symptoms

      By HectorConvector · Posted

      Evidence from normoglycaemic studies shows that healthy people peak at ~1 hour, and they then return to baseline in 2–3 hours, not 1. CGM shows normal post-meal rises even in metabolically healthy subjects. Clinical tests use the 2-hour value to judge normal glucose clearance. Therefore the 1-hour-back-to-fasting claim contradicts both physiology and clinical diagnostic standards.
    • HectorConvector
      Terrible Neurological Symptoms

      By HectorConvector · Posted

      I'm not sure what you're referring to as "normal" here - and is this something your doctor has mentioned (in bold)? As that isn't what any study or official information says. According to diabetes UK and the British Heart Foundation, normal fasting blood sugar is 4.9-5.4mmol/L. Normal by 2 hours from the start of a meal is anywhere below 7.8mmol/L. Random (more than 2 hours after a meal) should be below 5.6mmol/L.  Not in any study of normoglyceamic individuals does blood sugar go down to less than 5.4mmol/L one hour from the start of a meal, and I don't see such numbers being considered a limit for one hour post prandial in any official definition of normal blood sugar ranges anywhere. It is basically impossible even for the most metabolically healthy individual to have a blood sugar level anything like a fasting number 1 hour only after eating a high carb meal. This is also why medical standards use the 2-hour postprandial value, not 1 hour. Blood sugar normally spikes at about 1 hour after a high carb meal.  For example this study shows that young, healthy normoglycaemic people experience a 1hr peak blood sugar level of about 6.5-7mmol/L before which the 2hr number returns to about 4.7mmol/L, slightly higher than the fasting number of that morning. https://pmc.ncbi.nlm.nih.gov/articles/PMC2769652/?utm_source=chatgpt.com Even a normal person isn't going to be seeing essentially fasting blood sugar numbers after any meal except for one with 0 carbohdrates contents.
    • HectorConvector
      Terrible Neurological Symptoms

      By HectorConvector · Posted

      My skin biopsy and MRI scan shows no signs of any type of nerve damage. Nothing consistent with demylination or peripheral nerve damage. On the contrary, the nerve function from the skin biopsy proved better than normal. I don't get any pins and needles or have any loss of nerve function. It's pain only.  Thiamin I take is 100mg a day in tablet. I used to test blood sugar a lot in the past, and it never correlated directly with the nerve pain. It has only correlated with increased exercise and stress. The after eating getting worse thing happens when the blood flow is directed to the stomach for digestion away from the peripheral areas, which is normal, but central sensitization has caused normal sensations to be turned into pain by the brain, according to the latest doctors, hence whey I am being referred to the pain clinic.
    • knitty kitty
      Terrible Neurological Symptoms

      By knitty kitty · Posted

      @HectorConvector, My blood glucose level would spike after I ate.  It wouldn't return to "normal" fasting blood glucose level for longer and longer.  Blood glucose level should return to normal an hour after eating.  Mine would take two hours, then three hours, then longer.  So over night fasting blood tests wouldn't necessarily be very high until they got really bad.  But the peripheral neuropathy would feel the worst while my glucose was too high.  My blood glucose meter confirmed this.   On top of all that, my Celiac disease was still undiagnosed at the time, and I was suffering from malabsorption and nutritional deficiencies.  The deficiencies in B vitamins affected not just insulin production in the pancreas, but also the nerves in my extremities.  Nerves need B vitamins to maintain the myelin sheath protecting the nerves (like the plastic coating on electrical wires) when they fire.  When the myelin sheath is not maintained, that "pins and needles" feeling starts and increases as more of the sheath is damaged.  My parathesia progressed until the "pins and needles" went from my toes all the way up to my thighs.   Without sufficient vitamins, I started slowly losing weight.  Our bodies will start using not only stored fat, but also tear down our own muscles to provide fuel for the body to stay functional.   I hope you don't have pre-diabetes or diabetes.  Most diabetics have a thiamine deficiency.   How much thiamine are you taking?  What form of Thiamine are you taking?  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.