Need some help with understanding Labs

[Familyguy101]

So in response to some odd symptoms my doc did a celiac test.  Results are as follows:

Endomysial Antibody IgA Negative

t-Transglutaminase (tTG) IgA <2

Immunoglobulin A, Qn, Serum <5

t-Transglutaminase (tTG) IgG 18

HLA-DQA1 and HLADQB1  Zero variants detected.

Biopsy Negative.

So the doc says I have celiac.  I'm new to all of this.  Are those results indeed in line with a celiac diagnosis?

Thanks in advance for any help!

[frieze]

 appears you have one + on labs, with a very low IgA, and + genes.  good luck

[cyclinglady]

Like Frieze stated, you have a positive TTG IgG and your Immunoglobulin A could be too low for the celiac IgA versions of the test to work.  Unfortunately, your biopsy did not reveal damage, but that could easily be due to the location of the damage.  The surface area of the small intestine is larger than the size of a tennis court!  So easy to miss spotty damage that could be also out of reach.   Your GI might have only taken a few samples (more than four is recommended).  It might be nice to see if you test positive on any of the other celiac antibodies tests (EMA and DGP).  

At this point, you can trial the gluten-free diet and see if your symptoms resolve.  Wait at least six months.  Read the Newbie 101 section of the forum licated under the “Coping” section.  After six months, ask your doctor to re-run the TTG IgG test (and maybe the DGP IgG test too), to see if your results come down.  

I am not good with the genes, but you might not have the standard or common celiac genes.  We have members who do not have theses genes, but do have celiac disease.  Not everyone falls under the standard bell curve.  

For example, I have never had a positive EMA or TTG test.  I test positive to only the DGP.  This is not common at all, but I still have celiac disease.  

If you have doubts, it might be nice to get a second GI opinion from a celiac-savvy GI.  I firmly believe in second opinions!