Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Genetic testing


Mags88

Recommended Posts

Mags88 Rookie

I was hoping someone can help interpret these results.  My doctor called and said I tested positive for dq2 and mailed this to me. From what I can tell, it looks like both of my genes are dq2.  Is this correct? 8ADA8168-8EAA-498B-96D5-7AF4802C47A5.webp.6bc689199231003022ea24479443407f.webp


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Mags88 Rookie
4 hours ago, Mags88 said:

I was hoping someone can help interpret these results.  My doctor called and said I tested positive for dq2 and mailed this to me. From what I can tell, it looks like both of my genes are dq2.  Is this correct? 8ADA8168-8EAA-498B-96D5-7AF4802C47A5.webp.6bc689199231003022ea24479443407f.webp

A little more to add.  From what I understand, you have two genes - one from your mom and one from your dad.  So my question is, does this mean both of the genes I inherited are celiac genes?  Or is this one gene composed of different parts?  Obviously, I’m no geneticist. ?

cyclinglady Grand Master

Hi!  

I have not had genetic testing, so I have not researched this topic well in terms of interpretation.  However, I do know that about 35% of the population carries the genes that MAY develop into celiac disease.  Only a tiny few actually develop celiac disease.  

If you suspect celiac disease, you should have the antibodies blood tests to start.  Genetic testing does not diagnose celiac disease.  It helps doctors rule out celiac disease.  If you do not have the genes, you can not develop celiac disease.  

You have the genes.  Do you have celiac disease?  See your primary care physician for testing.  If positive, you probably need to see a Gastroenterologist.  

Why did you get the gene test?  

 

Mags88 Rookie

I have been gluten free for about 8 months with occasional glutenings, so the celiac panel is out of the question for me.  I have been to a gastroenterologist and she is doing a endoscopy on Tuesday just to check for any damage still in my small intestine.  My symptoms were pretty severe, so together we opted for the genetic testing instead of a gluten challenged because of how bad it would be for my health.  

I understand that it isn’t an official diagnosis, but with all of the symptoms and the gene, I’m ok with accepting it as “my diagnosis”.  My question is did I get the gene from my mom AND my dad.  Is there a way to know that from my blood results? I realize I can’t know which one it came from, but is there a way to know if it came from one or if it came from both?  Thanks!! 

cyclinglady Grand Master

Thanks for providing more information.  Unfortunately, I can not help you with determining who gave you the genes that could develop into celiac disease.

It does sound like you are still struggling.  Consider the Fasano diet which basically is no processed foods or eating out until you see improvement.  In theory, celiacs should heal pretty fast.  Usually learning the gluten-free diet is the real reason for most celiacs to feel unwell for so much longer.  Mistakes are so easy to make.  Most forum members report taking a year to two to finally feel well.  

Make sure the GI rules out other illnesses as well.  Good luck!  

 

Mags88 Rookie

Thank so much for the input! It is very tricky! 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      130,216
    • Most Online (within 30 mins)
      7,748

    zappanh
    Newest Member
    zappanh
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.3k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • max it
    • trents
      Not to eat or drink certain ones of what? Do you know what it is specifically you are trying to avoid when you eat? I kind of get the feeling you don't really understand much of this celiac thing.
    • max it
      Hi Ya , yes I have access to my records. Now if I only knew what I was looking for?? But for me this not important. I already know not to eat or drink certain ones. And I also push the packet on occasionally. Whatnisnto be learned? What's the value to be learned?
    • trents
      Hello, Jeff and yes, PTL! The word "marker" is typically used in connection with gene testing but gene testing is not usually where testing for celiac disease starts. It usually starts with blood work looking for antibodies that are more or less specific to celiac disease. The most popular antibody test ordered by doctors is the tTG-IGA test but there are others. Here is an overview: Do you have access to your medical record/test results online? What is your next step with this? I assume you are not yet eating gluten free.
    • knitty kitty
      @lizzie42, I have dermatitis herpetiformis outbreaks when I am exposed to foods high in iodine.  Iodine can cause dermatitis herpetiformis to flair up badly.  So I avoid high iodine foods like dairy products, crustaceans (shrimp, crab, lobster, shellfish), Eggs, and iodized table salt.  Spinach,  potatoes, kale, and kelp are high in iodine, too. The antibodies that cause dermatitis herpetiformis are tTg 3 IgA.  The tests for Celiac Disease measure tTg 2 IgA antibodies.  The dermatitis herpetiformis tTg3 antibodies can hang around for two years or more and become more active when exposed to iodine without having gluten present.  Dermatitis Herpetiformis is pressure sensitive and are apt to form under tight clothing like belts, bras and underwear, seams on tight clothing, etc.   I find tallow balm (Vintage Traditions is my favorite gluten free brand) eases the itching and helps heal the blisters without scaring.  Niacin Vitamin B 3 helps the body rid itself of the dermatitis herpetiformis antibodies.  Niacin is one of eight essential B vitamins which should all be supplemented together because they all work together in concert.  Niacin is instrumental in the body's production of Serotonin, the feel good neurotransmitter.  The body turns Niacin into Tryptophan, which is used to make Serotonin.  So when I have dermatitis herpetiformis flairs, I also take Tryptophan at bedtime, and Niacin and a B Complex during the day.   Hope this helps!  I know how miserable dermatitis herpetiformis can be.  
×
×
  • Create New...