Genetics

[Adgale]

Hi!. Anybody here with these genes?. I have only  the *05:05 allele in one geen And i know that only  0,05% of people  with these genes develop celiac disease, i've read that it's extremely rare to develop celiac with these genetics. I've been months and  months with gut inflammation  because of an allergy that i  have. It's a protein contained in all vegetal kindom and not all food afeccts me the same way but almost everything slow down my digestion and irritate my gut. I also want to say that i was 3 months in a gluten free diet but i ate a little bit in the second month for two days. After the third month i had biopsy to see the gut. It was negative, no villi damage and no lymphocytosis, but also, no antitransglutaminase antibodies. I also remeber one year ago when i was eating gluten that antitransglutaminase was negative too. I know that cereals contain alot of the protein that i'm allergic to, but i don't know, it's the only thing that cause me diarrhea. So, i don't know what the ell is happening, i don't know if its because of the allergie o who knows. last week i eat gluten free oat meal and 6 hours later was in the badroom with diarrhea... So guys what do you think, i'm so confused. Thank you so much for your suport!. These are my genes: 

DQX/DQ7.5  Or this way DQX.5.

I only have one copy of DQA1 *05:05. 

Edited September 29, 2019 by Adgale

[Ennis-TX]

  On 9/29/2019 at 10:34 PM, Adgale said:

Hi!. Anybody here with these genes?. I have only  the *05:05 allele in one geen And i know that only  0,05% of people  with these genes develop celiac disease, i've read that it's extremely rare to develop celiac with these genetics. I've been months and  months with gut inflammation  because of an allergy that i  have. It's a protein contained in all vegetal kindom and not all food afeccts me the same way but almost everything slow down my digestion and irritate my gut. I also want to say that i was 3 months in a gluten free diet but i ate a little bit in the second month for two days. After the third month i had biopsy to see the gut. It was negative, no villi damage and no lymphocytosis, but also, no antitransglutaminase antibodies. I also remeber one year ago when i was eating gluten that antitransglutaminase was negative too. I know that cereals contain alot of the protein that i'm allergic to, but i don't know, it's the only thing that cause me diarrhea. So, i don't know what the ell is happening, i don't know if its because of the allergie o who knows. last week i eat gluten free oat meal and 6 hours later was in the badroom with diarrhea... So guys what do you think, i'm so confused. Thank you so much for your suport!. These are my genes: 

DQX/DQ7.5  Or this way DQX.5.

I only have one copy of DQA1 *05:05. 

Expand Quote  

From a brief look the DQ7 gene is linked to celiac and the DQA1 05.05 is linked to crohns...the latter can be a real issues as everyone has different food triggers.

For celiac testing...you have to be eating 1-2 slices of bread worth of gluten daily for suggested 12 weeks for it to show up for the blood test or 2 weeks? for the endoscope and damage.

I have a odd gene snippet that got me my Celiac and none of the main genes...

[Adgale]

Really the only thing that i'm worried about is of have to be constantly looking at the cross contamination, that's the real problem for me

Edited September 30, 2019 by Adgale