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Celiac.com Article:Researchers Test ZED1227 Oral Transglutaminase 2 Inhibitor for Celiac Disease Treatment


Scott Adams

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    • knitty kitty
      Progesterone stimulates the thyroid.  The thyroid stimulates the immune system which increases production of IgG antibodies.   Progesterone Upregulates Gene Expression in Normal Human Thyroid Follicular Cells https://pmc.ncbi.nlm.nih.gov/articles/PMC4454767/ Celiac Disease and Autoimmune Thyroid Disease: The Two Peas in a Pod https://pmc.ncbi.nlm.nih.gov/articles/PMC9312543/  
    • knitty kitty
      @Mettedkny, Have you had your thyroid checked lately?  People with thyroid problems like Hashimoto's thyroiditis produce tTg IgG antibodies whether exposed to gluten or not.  Hashimoto's is another autoimmune disease frequently found with Celiac disease.  Do you eat iodized salt or sea salt?   P. S.  Progesterone stimulates the thyroid.  The thyroid stimulates the immune system which increases production of IgG antibodies.   Progesterone Upregulates Gene Expression in Normal Human Thyroid Follicular Cells https://pmc.ncbi.nlm.nih.gov/articles/PMC4454767/ Celiac Disease and Autoimmune Thyroid Disease: The Two Peas in a Pod https://pmc.ncbi.nlm.nih.gov/articles/PMC9312543/
    • trents
      Then it sounds like the thing you really need to focus more on is being more consistent with the gluten-free diet. Another suggestion I would make is to avoid using a lot of pre-made gluten-free food. Gluten-free facsimile flours are not enriched like their wheat counterpart and are full of empty calories. Focus on naturally gluten free foods that are nutrient and calorie dense. Have you had your vitamin D3 levels checked?
    • Sarawiththeceliac
      I know that but they make my sides hurt , believe me I think I have very poor absorbtion I take iron and it doesn't go up , vitamins and everything else the test results are the same from the last year 
    • trents
      It's normal for the pee to turn yellow when taking large doses of B vitamins, particularly riboflavin (B2). That doesn't mean they are building up in the kidneys. It means the excess is being excreted. The B vitamins are water soluble. 
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