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How long does it take elevated igG and IgA and TTG AB IGA to decline after starting a Gluten free diet?


Termite

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Termite Newbie

Timeline- Years of pain and constant illness: abdominal pain, felt like I was going to pass out, diarrhea, vomiting( within 30 min to hour of eating) migraines daily, hurt all over, depression, brain fog, fatigue. I caught every bug out there. Seemed to be always sick. Had to be on codeine/Tylenol mix for a time for my physical pain.

I dug up some older test results.

October 2007 - blood tests that did not include referenced items in my Topic title. However, a couple do indicate per my research today of the  possibility of Celiac disease because they were on the low or high end of the normal range. Those were Alkaline Phosphatase 33 (33-115 U/L) and Total Protein 8.1 (6.2-8.3 G/DL). When I researched what these items were, even though they say the lows and the high ends of each are within "normal" it could still be indicative of celiac disease or a few other things. Interesting.

November 2007 - Had test because of severe pain. Lipase was slightly elevated 61 (7-60 U/L). Amylase was 64 and in normal range apparently (21-101). Per my research today, elevated lipase could be indicative of Celiac disease.

January 2008 - Doctor tested for Amylase, Don't know why. (She didn't test for Lipase, the previously elevated one). Amylase elevated a bit but still in normal range. Increase from 64-77.

May 5th 2009 - My boss sent me home from work. He said I looked like death. He told me not to come back to work till I found someone smarter than my doctor to figure out my mystery illness. I was pale and around 100lbs. I was 38 yrs old at this time.

May/June 2009- I did discover about gluten from watching a celebrity on tv talk about a diet. I tried to tune her out because I am not into "diets". But then alot of what she said made sense to me, specifically...." If I dont eat, I feel better" That was me! So I researched all about celiac and gluten and its associated symptom( and it looked like me to a "T") for 3 days and formulated my shopping trip and meals. I never got sick again. I did this for 3 weeks and then intentionally reverted back to see what would happen and I got sick quickly. So i went Gluten-Free.

July 2009 - I went back to my doctor. I don't know if this was an already scheduled appt or if I made this appt to tell her I found the answer to my health issues. Yes, she was unkind and berated me for putzing around with my health all those years, yet she herself could not find what was wrong with me. She knew nothing about celiac or gluten. Anyway, she did have me do tests at this time, the ones referenced in my topic. Interesting since she told me she didnt know about celiac or gluten, that she would choose these tests.

The results: Ab IgG Reference range (<20) AU my score a 2, IgA same refence range, my score a 2, TTG AB IGA same range, my score a 3. Now I had been gluten free since starting May 10th 2009 for 3 weeks, Ate it for a day then back to Gluten-Free diet till testing on July 28th 2009. I am a little over 2.5 months of gluten free at this time of testing.

Just curious if ranges can drop that much to be negative for celiac in 2.5 months of the diet and could I still be celiac (if I am) even with this low numbers? Or just intolerant? If I do eat gluten now I don't react as quickly or severely unless I consume gluten for several months( I did that, I wont ever do it again).

Thank you

Sorry my post is so long.

 

 

 

 

 


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trents Grand Master

Welcome to the forum, Termite!

Amylase and lipase are pancreatic enzymes. Were you ever diagnosed with pancreatitis? Many of your symptoms point to that. However, the pancreas empties into the small bowel which is the part of the GI track that experiences inflammation from celiac disease.

Yes. Blood antibody levels can drop significantly in 2.5 months of eating gluten free. As a matter of fact, the Mayo clinic guidelines for an antibody pretest gluten challenge is the daily consumption of the amount of gluten found in two slices of wheat bread for 6-8 weeks. 2.5 months exceeds that window. So, your testing was likely invalid.

However, regardless of whether you have celiac disease of NCGS (Non Celiac Gluten Sensitivity), which share many of the same symptoms, the antidote is the same, elimination of gluten from the diet. There is no test for NCGS. celiac disease must first be ruled out.

knitty kitty Grand Master

@Termite, Welcome to the forum!

If you can't tolerate the eight weeks of gluten challenge for testing of antibodies against gluten in the blood as @trents mentioned, testing for any genes for Celiac Disease and positive response on a gluten free diet may be taken as a diagnosis for Celiac Disease by some doctors.  

Keep us posted on your progress!

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