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Flattened villi/ villi atrophy ???


Courtney541

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Courtney541 Rookie

Forgive me for the million post. I’m very newly diagnosed with the only advice from my physician over the phone being, “we think you have celiac so don’t eat gluten” 

so I’ve been in the depths of google and purchased some books. One thing I noted is whenever they talk about celiac and introduce it, it talks about flattened villi or villi atrophy. What does this mean?

my lab report specifically says “normal Villus architecture” (but has increased lymphocytes) I do not know what this means, or if it’s the same and the books just refer to differently. 
 

i read that doctors don’t diagnose celiac until marsh 3, but it also seems that’s not always true, what is everyone’s experience?


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RMJ Mentor

Flattened/atrophied villi are NOT the same thing as increased intraepithelial lymphocytes. Both are evaluated on a biopsy. This link describes the Marsh grades - looks like you’re Marsh 1?  If you have celiac disease it is at a very early stage.  Do you have any symptoms that led to testing?

Marsh classification

Courtney541 Rookie
4 minutes ago, RMJ said:

Flattened/atrophied villi are NOT the same thing as increased intraepithelial lymphocytes. Both are evaluated on a biopsy. This link describes the Marsh grades - looks like you’re Marsh 1?  If you have celiac disease it is at a very early stage.  Do you have any symptoms that led to testing?

Marsh classification

Thank you! No I didn’t have symptoms I was having an endoscopy for preventive reasons. Basically I started colonoscopies early and they figured may as well. 
 

One of my celiac blood work test came out as a weak positive, one of the standard range and one came back typical 

 

they are redoing the blood work 

  • 3 weeks later...
Scott Adams Grand Master

Be sure to keep eating gluten daily, at least 2 slices of wheat bread's worth, for 6-8 weeks before blood tests, and 2 weeks before a biopsy, otherwise you could get false negative results, or "weak" positive, which is still positive by the way.

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