Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Do these biopsy results look like Celiac?


JenniK

Recommended Posts

JenniK Contributor

I had an endoscopy and colonoscopy recently for chronic upper abdominal pain, which i thought was an ulcer, but they didn’t find one. I have been gluten-free for 3 or so (?) years now with presumed celiac. Gastroenterologist told me before procedures that he cannot (most likely) diagnose celiac because i was gluten-free for long time before seeing him. These results were posted by the pathologist, but I still haven’t had the Dr explain to me what he thinks. There seem to be several problem areas. Keep in mind that i was not knowingly eating gluten before endoscopy. A-C are gastric. D,E are colon. (A different part of the report also said “diffuse inflammation” and “reactive gastritis”. Thanks in advance

A. Fragments of small intestinal mucosa show normal villous architecture without intraepithelial lymphocytosis. A normal complement of
chronic inflammatory cells is present in the lamina propria without acute or granulomatous inflammation. runner's glands are present.
There is no metaplastic change, dysplasia, or malignancy.
B. Fragments of gastric antral and oxyntic mucosa show foveolar hyperplasia and smooth muscle hypertrophy and few foci of chronic
inflammatory cells within the lamina propria without acute or granulomatous inflammation. There is no intestinal metaplasia, dysplasia, or
malignancy. Features typical of Helicobacter pylori are not seen.
C. The sections show oxyntic type gastric mucosa with normal surface maturation and rare cystically dilated crypt lined by foveolar
epithelium. Normal minimal inflammatory infiltrates are present within the lamina propria. Acute or granulomatous inflammation is not
identified. Features of Helicobacter gastritis are not identified. Intestinal metaplasia, dysplasia, or malignancy are not identified.
imer
D. E. Colonic mucosa shows crypt hyperchromasia with elongation and pseudostratification of the nuclei. Features of high-grade
dysplasia are not identified.
Unless otherwise specified, formalin-fixed paraffin-embedded sections and all routine, IHC, or special stains are performed at


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Scott Adams Grand Master

The results seem negative for celiac disease, but I would agree with your doctor here with their conclusion that the results could not be used to diagnose celiac disease since you were gluten-free for so long before the endoscopy. 

Given that you've been gluten-free for so long, how important is it to you to have a formal diagnosis? Your private life and/or health insurance premiums my go higher with a diagnosis, so keep this in mind.

You could do this again after going at least two weeks on a gluten diet where you eat 2 slices of wheat bread daily beforehand. 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,555
    • Most Online (within 30 mins)
      7,748

    Barbara wright
    Newest Member
    Barbara wright
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.5k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • trents
      Ichthus is the Greek word (using English letters) for fish. The letters in the actual Greek word form an acronym that come from the first letters in the Greek words for "Jesus", "God's Son," "Savior".   Now, back to your family's denial of your celiac disease, I think you can relate to this:  
    • Mantooth
      Thanks for the kind words. It's hard to convince my doctor to investigate further because of a negative blood test and he only tested me for one marker. 🙃 I've come to the point where I need to take this into my own hands because the doctors are infuriating and it's not going anywhere. I've been gluten free for a week and feeling better but I was still consuming dairy and I think that's what's backing me up. Next week no dairy introduced. 
    • nanny marley
      Hello mantooth nice to meet you it's so uncanny what you wrote you sound just like me even the back issues are exactly the same and I'm new here too trying to find out if I have the same had I too have been struggling to find answers with my docters I don't have a diagnosis but I've been struggling like forever and was told ibs and health aniexty was my problem but on researching I've come to the conclusion it's probably more because i cut gluten and lactose out for 6 months and  it was a incredible change for me so although I can't help with diagnosis I can say your not alone in trying  to find answers 😊
    • nanny marley
      I call it the fish because I can't spell the other word at times 🤣 don't want to make myself look silly but yes I have this symbol on many items so nice to see it today wen I'm needing help  gives me faith I'm on the right track 
    • nanny marley
      Yes I have the fish symbol on my car and my ring 🙏 and yes I've been going for years to the docters but I got that feed up ov having to avoid eating out or even visiting people threw aniexty of needing the toilet or of gas or sickness I did some research of my own and I did the elimination diet and what a difference I've had my family think I'm nuts at times saying it's in my head it won't help until they now are doing it too because my daughter's are facing the same issues it's made me feel so ill at times it's so crazy how food can do this to you one night I was up 6 times to the point I had nothing left in my body I didn't go to the toilet for days after and I felt sick has a dog I'm so glad I found this forum I feel a little more human already 😄
×
×
  • Create New...