mcas Mast Cell Activation Syndrome (MCAS)

[Bronwyn W]

Up-front, I cannot express my gratitude sufficiently. Thank you so much for all you highly valuable and much appreciated support 🙏🏻

Please can you advise what tests I should have for a diagnosis on mast cell activation syndrome (mcas) and/or histamine intolerance and h.pilori? Are histamine intolerance and mcas thr same thing?

Kind regards, 

Bronwyn 

[trents]

Histamine intolerance and MCAS go hand in hand. If you have histamine intolerance, you will have MCAS and vice versa. I'm not saying they are exactly the same thing but I'm saying you really can't separate the two. Another way putting it is that MCAS is the root cause of histamine intolerance. If you want information on diagnosing MCAS just google it. Or, you might try going on a low histamine diet to see if your symptoms improve. I don't think there is a cure for MCAS but a slow histamine diet can help manage it. To some degree, antihistamine therapy (zyrtec, allegra) helps control the symptoms but you may still have outbreaks at times. There are many things that contribute to histamine levels in the body including environmental and seasonal allergies. It's not just what you eat but that is the one thing you can exercise some control over.

[knitty kitty]

@Bronwyn W,

I don't believe a diagnosis is necessary for histamine intolerance.  

Our bodies can make histamine.  Mast cells (a type of immune cell) release histamine in our bodies in reaction to perceived invaders like bacteria, viruses, and gluten. 

Our food contains histamine.  Some foods contain higher levels of histamine than others.  High histamine foods include fermented foods, citrus fruits, crustaceans, and more.

Our bodies can breakdown histamine.  Trouble arises when our bodies and our foods have levels of histamine that our bodies cannot clear fast enough and "our cup runneth over."

Our bodies need certain essential vitamins to breakdown histamine.  Vitamins like Vitamin C, and Cobalamine B12.  Vitamin D helps with immunoregulation.

Thiamine Vitamin B 1 helps Mast Cells to hold their wad and not release histamine.  Mast cells will degranulate and release excessive histamine when there is thiamine deficiency.  

These are all vitamins that are frequently low or deficient in newly diagnosed Celiacs.  Checking for nutritional deficiencies is part of proper follow up care for Celiac patients.  Celiacs are often low in essential vitamins and minerals across the board because of the damage done to the small intestine where nutrients are absorbed.  

Try the Autoimmune Protocol Diet and choose low histamine foods.  Supplement with the eight essential B vitamins, magnesium glycinate, Vitamin D, Vitamin C, and zinc.  

I followed the Low Histamine AIP diet and supplemented with extra Thiamine in addition to the nutrients listed above.  The extra Thiamine really helped with mast cell degranulation.  My reactions to high histamine foods became less quite quickly.  

https://www.healthline.com/nutrition/aip-diet-autoimmune-protocol-diet

The book The Paleo Approach  by Dr. Sarah Ballantyne was extremely helpful.  She is a Celiac herself and designed the diet for herself and her family.  This diet has been scientifically shown to reduce inflammation and promote healing in the digestive tract.

For H. Pylori infection you will need to be tested by a doctor.

 Hope this helps!

[Bronwyn W]

  On 8/9/2023 at 8:17 PM, knitty kitty said:

@Bronwyn W,

I don't believe a diagnosis is necessary for histamine intolerance.  

Our bodies can make histamine.  Mast cells (a type of immune cell) release histamine in our bodies in reaction to perceived invaders like bacteria, viruses, and gluten. 

Our food contains histamine.  Some foods contain higher levels of histamine than others.  High histamine foods include fermented foods, citrus fruits, crustaceans, and more.

Our bodies can breakdown histamine.  Trouble arises when our bodies and our foods have levels of histamine that our bodies cannot clear fast enough and "our cup runneth over."

Our bodies need certain essential vitamins to breakdown histamine.  Vitamins like Vitamin C, and Cobalamine B12.  Vitamin D helps with immunoregulation.

Thiamine Vitamin B 1 helps Mast Cells to hold their wad and not release histamine.  Mast cells will degranulate and release excessive histamine when there is thiamine deficiency.  

These are all vitamins that are frequently low or deficient in newly diagnosed Celiacs.  Checking for nutritional deficiencies is part of proper follow up care for Celiac patients.  Celiacs are often low in essential vitamins and minerals across the board because of the damage done to the small intestine where nutrients are absorbed.  

Try the Autoimmune Protocol Diet and choose low histamine foods.  Supplement with the eight essential B vitamins, magnesium glycinate, Vitamin D, Vitamin C, and zinc.  

I followed the Low Histamine AIP diet and supplemented with extra Thiamine in addition to the nutrients listed above.  The extra Thiamine really helped with mast cell degranulation.  My reactions to high histamine foods became less quite quickly.  

https://www.healthline.com/nutrition/aip-diet-autoimmune-protocol-diet

The book The Paleo Approach  by Dr. Sarah Ballantyne was extremely helpful.  She is a Celiac herself and designed the diet for herself and her family.  This diet has been scientifically shown to reduce inflammation and promote healing in the digestive tract.

For H. Pylori infection you will need to be tested by a doctor.

 Hope this helps!

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Fantastic 🙏🏻 Thank you so much for giving me this useful direction to pursue