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positive for DQB1*02, one half of the DQ2 heterodimer.


AnthonyA333

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AnthonyA333 Newbie

Can someone please help me understand these results… Final Results:
DQB1*02:EEMYK,05:EEMYB
DQA1*01:EENPT,02:EEMYJ
Code Translation:
Previous Result and Date

   EEMYB
05:01/05:12/05:18/05:20/05:27/05:30/05:31
/05:32/05:44/05:45/05:103/05:104/05:107
/05:133/05:137/05:139/05:144/05:148/05:150
/05:152/05:155/05:158/05:159/05:160/05:162
/05:163/05:164/05:167/05:169/05:171/05:173
/05:176/05:177/05:183/05:184/05:185N
/05:188/05:190/05:193/05:194/05:195/05:197
/05:216/05:217/05:219/05:223/05:225/05:226
/05:228/05:230/05:232/05:234/05:237/05:246
/05:248/05:249/05:252/05:256/05:263/05:267
/05:268/05:270/05:271/05:272/05:275/05:277
/05:279/05:283N/05:286/05:288/05:290
/05:291/05:295N/05:297/05:298/05:299/05:300
01/03/04/05/07/08/09/10/11/12/13/14/15/16
/17/19/20/21/22/23/24/25/26
02:02/02:11/02:12/02:20N/02:26/02:50/02:62
/02:65/02:71/02:80/02:84/02:89/02:95/02:97
/02:110/02:116/02:117/02:120/02:122/02:124
/02:126/02:127/02:131/02:137/02:138/02:142
/02:143/02:145/02:146/02:147/02:150/02:153
/02:156/02:161/02:165/02:167N/02:171Q
/02:172/02:175/02:176N/02:179/02:187
/02:194N/02:199/02:200/02:201/02:203
/02:204N
01:01/01:04/01:05/01:12/01:18/01:22/01:27
/01:29/01:35/01:37/01:49/01:53/01:55/01:60
/01:61/01:64/01:66/01:67/01:80/01:83/01:86
/01:88N/01:89/01:95/01:96/01:98/01:99
EEMYJ EEMYK
EENPT
The patient is positive for DQB1*02, one half of the DQ2
heterodimer.  The Celiac Disease risk from the HLA DQA/DQB
genotyp


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Wheatwacked Veteran

"Patients with DQ2, half DQ2 and/or DQ8 are predisposed to celiac disease. A negative result essentially rules out celiac disease.    Celiac disease can present with gastrointestinal symptoms and/or widely variable non-gastrointestinal findings such as iron deficiency anemia, dermatitis herpetiformis, osteoporosis, chronic fatigue, short stature, neurologic symptoms, and many more. Gastrointestinal symptoms are present in fewer than 50% of cases of systematic celiac disease."   Celiac HLA DQ Association

What prompted you to get this test? Have you had other symptoms?  Blood tests or biopsy?

AnthonyA333 Newbie

I had a weak positive of  

t-Transglutaminase (tTG)

A IgG °2

it was 7 

Wheatwacked Veteran

Tissue Transglutaminase Antibodies (tTG-IgA) test will be positive in about 98% of patients with celiac disease who are on a gluten-containing diet. ... The same test will come back negative in about 95% of healthy people without celiac disease... The tTG test is the most sensitive test for celiac disease.

Doctor's opinion?

Do you perhaps have vitamin D plasma, homocystein, B12, folate test results that might indicate nutritional deficiencies and inflammation?

While this test is accurate, there are other autoimmune diseases that can give this response, Having other autoimmune diseases does not preclude Celiac Disease.

Your choice is get more complete testing done and a Celiac endoscopy biopsy done, or if you don't care about a medical diagnosis, start a strict gluten free diet and evaluate.  Malabsorption Syndrome is common in Celiac Disease so pay attention to your essential nutrient intake.  Your symptoms will help guide you to what you need to supplement. Low or deficient Vitamin D seems to be ubiquitous in all the autoimmune diseases so a good place to start.

Products allowed/disallowed in the Gluten Contamination Elimination Diet

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