The journey begins

[Penguintummy]

Hi guys, newbie here, I’ll keep the journey up to now brief. 18 months, thoughts it was crohns but colonoscopy came back negative and so did biopsies.

so they run some blood tests and told me I was equivocal and needed to be referred for endoscopy and biopsy 

the values were as follows 

 

IGA - 1.3 ( no idea on measurements used it’s not on my bloods report) 

ttg - IGa - 13 u/ml

Ttg igg - <0.1 u/ml 

 

so the Ttg IGa is postive the other Ttg is negative and no idea about the IGa as no reference ranges 

as a small back story I’ve also been diagnosed with adhd, ocd, I have asthma and eczema (dishydrotic and normal), bad skin in general, then I won’t even go into all the GI issues 

 

so my question is how likely is it I got a false positive on the ttg- IGa 

is that even possible? 

[Penguintummy]

3 minutes ago, Penguintummy said:

Hi guys, newbie here, I’ll keep the journey up to now brief. 18 months, thoughts it was crohns but colonoscopy came back negative and so did biopsies.

so they run some blood tests and told me I was equivocal and needed to be referred for endoscopy and biopsy 

the values were as follows 

 

IGA - 1.3 ( no idea on measurements used it’s not on my bloods report) 

ttg - IGa - 13 u/ml

Ttg igg - <0.1 u/ml 

 

so the Ttg IGa is postive the other Ttg is negative and no idea about the IGa as no reference ranges 

as a small back story I’ve also been diagnosed with adhd, ocd, I have asthma and eczema (dishydrotic and normal), bad skin in general, then I won’t even go into all the GI issues 

 

so my question is how likely is it I got a false positive on the ttg- IGa 

is that even possible? 

Probably should add the reference ranges for the Ttg tests 

 

<7 negative 

7-10 equivocal 

>10 positive 

so Ttg IGa postive Ttg igg negavtive 

[trents]

Not sure what meaning you are loading "false positive" with. The test is positive but on the low end so if the question is could the positive point to something else besides celiac, the answer is, yes, but a small chance that such is the case. It's too bad such a limited number of tests were deployed as additional testing could have given a more complete picture. The other question is the IGA 1.3 test report item. Is that total serum IGA? If that is low it can create false negatives or lower positives for the individual celiac antibody tests. Here is a primer on celiac antibody testing:

The next logical step is an endoscopy with biopsy of the small bowel villous lining to check for the damage typically caused by celiac disease to that membrane. If you will be pursuing this, remain on regular amounts of gluten until the procedure is accomplished.

[Penguintummy]

1 hour ago, trents said:

Not sure what meaning you are loading "false positive" with. The test is positive but on the low end so if the question is could the positive point to something else besides celiac, the answer is, yes, but a small chance that such is the case. It's too bad such a limited number of tests were deployed as additional testing could have given a more complete picture. The other question is the IGA 1.3 test report item. Is that total serum IGA? If that is low it can create false negatives or lower positives for the individual celiac antibody tests. Here is a primer on celiac antibody testing:

The next logical step is an endoscopy with biopsy of the small bowel villous lining to check for the damage typically caused by celiac disease to that membrane. If you will be pursuing this, remain on regular amounts of gluten until the procedure is accomplished.

Probably should add the reference ranges for the Ttg tests 

 

<7 negative 

7-10 equivocal 

>10 positive 

so Ttg IGa postive Ttg igg negavtive 
 

i think it’s total serum IGa that’s 1.3 but it doesn’t actually say and it doesn’t have a reference range either 

I know it’s not endoysimal IGa because that has no value next to it 

 

false positive I mean the Ttg IGa is positive as it’s over 10 but could something else cause that? 
I know my thyroid is normal as they checked that too I also have a raised crp level and raised eosinophils 

 

Thankyou I’ll read that article 

I also think at first they were my looking at Crohn’s disease but that looks unlikely so they are now looking at celiac as well as my pancreas function 

I have more bloods this week not a clue what’s being tested this time 

as well as an mri